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In utero and early-life exposure of rats to a Wi-Fi signal: screening of immune markers in sera and gestational outcome.

Bioeffects Seen

Aït-Aïssa S, Billaudel B, Poulletier de Gannes F, Ruffié G, Duleu S, Hurtier A, Haro E, Taxile M, Athané A, Geffard M, Wu T, Wiart J, Bodet D, Veyret B, Lagroye I. · 2012

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Researchers found no change in immune markers in young rats exposed to a Wi-Fi signal before and after birth, and observations suggested a lack of adverse effects on delivery.

Plain English Summary

Summary written for general audiences

Pregnant rats were exposed to a 2.45 GHz Wi-Fi signal for 2 hours per day, 5 days per week, at whole-body SAR levels of 0, 0.08, 0.4, and 4 W/kg. Dams were exposed from days 6 to 21 of gestation, and then three newborns per litter were further exposed from birth to day 35 postnatal. Sera from pups were screened for antibodies against 15 different antigens using ELISA, and no change in humoral response was observed regardless of the types of biomarker and SAR levels. The researchers' observations suggested a lack of adverse effects of Wi-Fi exposure on delivery and general condition of the animals.

Why This Matters

The study assessed immunological biomarkers in the sera of young rats exposed in utero and postnatal to non-ionizing radiofrequency fields. In addition to immune markers, the study monitored body mass of dams and pups, litter size, and anogenital distance as indicators of gestational and developmental outcome.

Exposure Details

SAR
0, 0.08, 0.4, and 4 W/kg
Source/Device
2.45 GHz
Exposure Duration
2 h/day and 5 days/week

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kg
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 2.45 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 2.45 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

An experimental approach was used to assess immunological biomarkers in the sera of young rats exposed in utero and postnatal to non-ionizing radiofrequency fields.

Pregnant rats were exposed free-running, 2 h/day and 5 days/week to a 2.45 GHz Wi-Fi signal in a rev...

No change in humoral response of young pups was observed, regardless of the types of biomarker and S...

Under these experimental conditions, our observations suggest a lack of adverse effects of Wi-Fi exposure on delivery and general condition of the animals.

Cite This Study
Aït-Aïssa S, Billaudel B, Poulletier de Gannes F, Ruffié G, Duleu S, Hurtier A, Haro E, Taxile M, Athané A, Geffard M, Wu T, Wiart J, Bodet D, Veyret B, Lagroye I. (2012). In utero and early-life exposure of rats to a Wi-Fi signal: screening of immune markers in sera and gestational outcome. Bioelectromagnetics. 33(5):410-420, 2012.
Show BibTeX
@article{s_2012_in_utero_and_earlylife_798,
  author = {Aït-Aïssa S and Billaudel B and Poulletier de Gannes F and Ruffié G and Duleu S and Hurtier A and Haro E and Taxile M and Athané A and Geffard M and Wu T and Wiart J and Bodet D and Veyret B and Lagroye I.},
  title = {In utero and early-life exposure of rats to a Wi-Fi signal: screening of immune markers in sera and gestational outcome.},
  year = {2012},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/22228576/},
}
PubMed: 22228576

Cited By (27 papers)

Quick Questions About This Study

The rats were exposed to a 2.45 GHz Wi-Fi signal in a reverberation chamber.
Sera were screened for antibodies directed against 15 different antigens related to damage and/or pathological markers, using ELISA.
No change in humoral response of young pups was observed, regardless of the types of biomarker and SAR levels.
The researchers' observations suggested a lack of adverse effects of Wi-Fi exposure on delivery and general condition of the animals.
Three newborns per litter were exposed from birth to day 35 postnatal.