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Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

Local exposure of 849 MHz and 1763 MHz radiofrequency radiation to mouse heads does not induce cell death or cell proliferation in brain

No Effects Found

Kim TH, Huang TQ, Jang JJ, Kim MH, Kim HJ, Lee JS, Pack JK, Seo JS, Park WY · 2008

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Chronic exposure to 849 MHz and 1763 MHz RF radiation at 7.8 W/kg SAR did not induce cell death, proliferation, or reactive gliosis in mouse brains.

Plain English Summary

Summary written for general audiences

Researchers used a carousel-type chamber to expose the heads of C57BL mice to 849 MHz or 1763 MHz RF radiation. Mice were irradiated intermittently at 7.8 W/kg for up to 12 months. Brain tissues collected at 6 and 12 months showed no differences in histology, cell proliferation, NeuN and GFAP expression in hippocampus and cerebellum, or cell death between exposure and control groups. Body weights did not differ among sham, 849 MHz, and 1763 MHz groups during the study.

Why This Matters

The study aimed to assess the effect of local mobile phone frequency irradiation on the mouse brain over 12 months. The authors concluded that chronic exposure at 7.8 W/kg SAR could not induce cellular alterations such as proliferation, death, or reactive gliosis.

Exposure Details

SAR
7.8 W/kg
Source/Device
849 MHz and 1763 MHz
Exposure Duration
repeated daily exposure, 1 h/day, 5 days/week, for 6 or 12 months

Exposure Context

This study used 7.8 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 7.8 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)This level is 5 times the FCC limit
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 849 MHz - 1.76 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 849 MHz - 1.76 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

To study the effect of local exposure of mobile phone frequency irradiation to the mouse brain for 12 months

We established a carousel-type exposure chamber for 849 MHz or 1763 MHz of mobile phone RF radiation...

The brain tissues were obtained from 3 groups at 6 months and 12 months to examine the differences i...

From these data, we conclude that the chronic exposure to 849 MHz and 1763 MHz RF radiation at a 7.8 W/kg specific absorption rate (SAR) could not induce cellular alterations such as proliferation, death, and reactive gliosis.

Cite This Study
Kim TH, Huang TQ, Jang JJ, Kim MH, Kim HJ, Lee JS, Pack JK, Seo JS, Park WY (2008). Local exposure of 849 MHz and 1763 MHz radiofrequency radiation to mouse heads does not induce cell death or cell proliferation in brain Exp Mol Med. 40(3):294-303, 2008.
Show BibTeX
@article{th_2008_local_exposure_of_849_2770,
  author = {Kim TH and Huang TQ and Jang JJ and Kim MH and Kim HJ and Lee JS and Pack JK and Seo JS and Park WY},
  title = {Local exposure of 849 MHz and 1763 MHz radiofrequency radiation to mouse heads does not induce cell death or cell proliferation in brain},
  year = {2008},
  
  url = {https://www.nature.com/articles/emm200834},
}

Quick Questions About This Study

The study used 849 MHz and 1763 MHz RF radiation at 7.8 W/kg.
No changes were found in histology or cell proliferation in brain tissues collected at 6 and 12 months. NeuN and GFAP expression in the hippocampus and cerebellum and cell death also showed no changes.
Body weights did not differ among the sham, 849 MHz, and 1763 MHz groups.
Mice were exposed intermittently for up to 12 months, and brain tissues were examined at 6 and 12 months.
A carousel-type exposure chamber was used to expose the heads of C57BL mice.