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Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

Brain & Nervous System

Impact of Long-Term RF-EMF on Oxidative Stress and Neuroinflammation in Aging Brains of C57BL/6 Mice.

No Effects Found

Jeong YJ, Son Y , Han NK, Choi HD, Pack JK, Kim N, Lee YS, Lee HJ. · 2018

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Long-term RF-EMF exposure did not change oxidative stress, DNA damage, apoptosis, astrocyte, or microglia markers, nor did it alter locomotor activity in aged mice.

Plain English Summary

Summary written for general audiences

The aim of the study was to observe the impact of long-term RF-EMF on oxidative stress and neuroinflammation in aging brains of C57BL/6 mice. Compared with young mice, aged mice showed significantly increased protein and lipid oxidative damage markers in the brain. Aged mice also had significantly elevated markers of DNA damage, apoptosis, astrocytes, and microglia. Long-term RF-EMF exposure did not change the levels of oxidative stress, DNA damage, apoptosis, astrocyte, or microglia markers in aged mouse brains. Long-term RF-EMF exposure also did not alter locomotor activity in aged mice.

Why This Matters

The researchers concluded that long-term RF-EMF exposure did not influence age-induced oxidative stress or neuroinflammation in C57BL/6 mice. Middle-aged C57BL/6 mice aged 14 months were exposed to 1950 MHz electromagnetic fields for 8 months at a SAR of 5 W/kg, 2 hours per day, 5 days per week.

Exposure Details

SAR
5 W/kg
Source/Device
1950 MHz
Exposure Duration
2 h/day, 5 d/week for 8 month

Exposure Context

This study used 5 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 5 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)This level is 3 times the FCC limit
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 1.95 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 1.95 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

The aim of this study is to observe the Impact of Long-Term RF-EMF on Oxidative Stress and Neuroinflammation in Aging Brains of C57BL/6 Mice

Middle-aged C57BL/6 mice (aged 14 months) were exposed to 1950 MHz electromagnetic fields for 8 mont...

Compared with those in the young group, levels of protein (3-nitro-tyrosine) and lipid (4-hydroxy-2-...

Therefore, these findings indicate that long-term exposure to RF-EMF did not influence age-induced oxidative stress or neuroinflammation in C57BL/6 mice.

Cite This Study
Jeong YJ, Son Y , Han NK, Choi HD, Pack JK, Kim N, Lee YS, Lee HJ. (2018). Impact of Long-Term RF-EMF on Oxidative Stress and Neuroinflammation in Aging Brains of C57BL/6 Mice. Int J Mol Sci. 2018 Jul 19;19(7). pii: E2103.
Show BibTeX
@article{yj_2018_impact_of_longterm_rfemf_2878,
  author = {Jeong YJ and Son Y  and Han NK and Choi HD and Pack JK and Kim N and Lee YS and Lee HJ.},
  title = {Impact of Long-Term RF-EMF on Oxidative Stress and Neuroinflammation in Aging Brains of C57BL/6 Mice.},
  year = {2018},
  
  url = {https://www.mdpi.com/1422-0067/19/7/2103},
}

Quick Questions About This Study

The study aimed to observe the impact of long-term RF-EMF on oxidative stress and neuroinflammation in aging brains of C57BL/6 mice.
Aging significantly increased protein and lipid oxidative damage markers as well as DNA damage, apoptosis, astrocyte, and microglia markers in the brain.
Long-term RF-EMF exposure did not change the levels of oxidative stress, DNA damage, apoptosis, astrocyte, or microglia markers in aged mouse brains.
Long-term RF-EMF exposure did not alter locomotor activity in aged mice.
Middle-aged C57BL/6 mice aged 14 months were exposed to 1950 MHz electromagnetic fields for 8 months at a SAR of 5 W/kg, 2 hours per day, 5 days per week.