Sensitivity of spiral ganglion neurons to damage caused by mobile phone electromagnetic radiation will increase in lipopolysaccharide-induced inflammation in vitro model.
Zuo WQ, Hu YJ, Yang Y, Zhao XY, Zhang YY, Kong W, Kong WJ. · 2015
View Original AbstractMobile phone radiation becomes significantly more damaging to nerve cells when they're already inflamed or stressed.
Plain English Summary
Researchers exposed rat auditory nerve cells to mobile phone radiation at 2-4 W/kg levels, with and without mild inflammation. Radiation alone caused no damage, but significantly harmed pre-inflamed cells, suggesting EMF exposure may be more dangerous when your body is already fighting inflammation.
Why This Matters
This research reveals a critical vulnerability that most EMF studies miss: the interaction between radiofrequency radiation and pre-existing cellular stress. The science demonstrates that cells already dealing with inflammation become significantly more susceptible to EMF damage, even at the 4 W/kg exposure level (which falls within typical mobile phone usage ranges). What this means for you is that EMF exposure may pose greater risks when you're already fighting infections, dealing with chronic inflammation, or under other forms of cellular stress. The reality is that most of us aren't operating with perfectly healthy cells all the time. This study suggests that the 'safe' exposure levels established for healthy tissue may not account for the increased vulnerability during illness, stress, or aging when inflammation is more common.
Exposure Details
- SAR
- 2, 4 W/kg
- Exposure Duration
- 24 h intermittent exposure
Exposure Context
This study used 2, 4 W/kg for SAR (device absorption):
- 5x above the Building Biology guideline of 0.4 W/kg
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
We established a lipopolysaccharide (LPS)-induced inflammation in vitro model to investigate whether the possible sensitivity of spiral ganglion neurons to damage caused by mobile phone electromagnetic radiation (at specific absorption rates: 2, 4 W/kg) will increase.
Spiral ganglion neurons (SGN) were obtained from neonatal (1- to 3-day-old) Sprague Dawley® (SD) rat...
LPS (100 μg/ml) induced DNA damage and suppressed cellular activity (P < 0.05). LPS (40 μg/ml) did n...
Short-term exposure to radiofrequency electromagnetic radiation could not directly induce DNA damage in normal spiral ganglion neurons, but it could cause the changes of cellular ultrastructure at special SAR 4.0 W/kg when cells are in fragile or micro-damaged condition. It seems that the sensitivity of SGN to damage caused by mobile phone electromagnetic radiation will increase in a lipopolysaccharide-induced inflammation in vitro model.
Show BibTeX
@article{wq_2015_sensitivity_of_spiral_ganglion_587,
author = {Zuo WQ and Hu YJ and Yang Y and Zhao XY and Zhang YY and Kong W and Kong WJ.},
title = {Sensitivity of spiral ganglion neurons to damage caused by mobile phone electromagnetic radiation will increase in lipopolysaccharide-induced inflammation in vitro model.},
year = {2015},
doi = {10.1186/s12974-015-0300-1},
url = {https://link.springer.com/article/10.1186/s12974-015-0300-1},
}