Deficits in water maze performance and oxidative stress in the hippocampus and striatum induced by extremely low frequency magnetic field exposure.
Cui Y, Ge Z, Rizak JD, Zhai C, Zhou Z, Gong S, Che Y. · 2012
View Original AbstractExposure to ELF-MF at 1 mT, 50 Hz was associated with oxidative stress in the hippocampus and striatum and impaired spatial and habit learning in mice.
Plain English Summary
Researchers examined the effects of extremely low frequency magnetic field (ELF-MF) exposure on learning in mice using two water maze tasks. ELF-MF exposure at 1 mT, 50 Hz was associated with oxidative stress in the hippocampus and striatum, and impaired both spatial learning and habit learning. The study provides evidence for an association between impaired learning and oxidative stress in the hippocampus and striatum induced by ELF-MF exposure.
Why This Matters
The researchers measured oxidative stress in two brain regions, the hippocampus and the striatum, and linked changes there to deficits in two different types of learning. The study characterizes the learning impairments as hippocampal-dependent spatial learning and striatum-dependent habit learning. The authors describe the association between learning impairment and oxidative stress as evidence, not as proof of a direct causal mechanism.
Exposure Details
- Magnetic Field
- 1 mT
- Source/Device
- 50 Hz
- Exposure Duration
- 4 hours per day
Exposure Context
This study used 1 mT for magnetic fields:
- 50Kx above the Building Biology guideline of 0.2 mG
- 10Kx above the BioInitiative Report recommendation of 1 mG
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
In this study, we examined the effects of ELF-MF exposure on learning in mice using two water maze tasks and on some parameters indicative of oxidative stress in the hippocampus and striatum.
We found that ELF-MF exposure (1 mT, 50 Hz) induced serious oxidative stress in the hippocampus and ...
This study provides evidence for the association between the impairment of learning and the oxidative stress in hippocampus and striatum induced by ELF-MF exposure.
Show BibTeX
@article{y_2012_deficits_in_water_maze_237,
author = {Cui Y and Ge Z and Rizak JD and Zhai C and Zhou Z and Gong S and Che Y. },
title = {Deficits in water maze performance and oxidative stress in the hippocampus and striatum induced by extremely low frequency magnetic field exposure.},
year = {2012},
url = {https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0032196},
}