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Spatial memory recovery in Alzheimer's rat model by electromagnetic field exposure.

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Akbarnejad Z, Esmaeilpour K, Shabani M, Asadi-Shekaari M, Saeedi-Goraghani M, Ahmadi M. · 2018

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Therapeutic-level magnetic fields (10 milliTesla) improved memory in Alzheimer's rats, showing EMF can have beneficial brain effects at specific intensities.

Plain English Summary

Summary written for general audiences

Researchers injected rats with Alzheimer's-causing proteins and then exposed them to magnetic fields (50 Hz at 10 milliTesla) for 14 days. The magnetic field exposure significantly improved memory and learning abilities in the Alzheimer's rats, as measured by maze tests. This suggests that certain electromagnetic fields might help protect brain function in neurodegenerative diseases.

Why This Matters

This study reveals a fascinating paradox in EMF research: while we typically focus on potential harms from electromagnetic field exposure, here we see therapeutic benefits. The 10 milliTesla magnetic field used is roughly 200 times stronger than typical household exposures (around 0.05 milliTesla near appliances), placing it in the realm of medical devices rather than everyday environmental exposure. What makes this research particularly compelling is that it demonstrates both protective and restorative effects on brain function. The magnetic field exposure not only prevented some cognitive decline when applied immediately after the Alzheimer's trigger, but also improved memory when applied weeks later after damage had already occurred. This adds important nuance to our understanding of how electromagnetic fields interact with biological systems, particularly the brain and nervous system.

Exposure Details

Magnetic Field
10 mG
Source/Device
50 Hz
Exposure Duration
14 consecutive days

Exposure Context

This study used 10 mG for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 10 mGExtreme Concern5 mGFCC Limit2,000 mGEffects observed in the Extreme Concern range (Building Biology)FCC limit is 200x higher than this exposure level

Study Details

This study aimed to investigate the effect of ELF-EMF exposure (50 Hz, 10 mT) on spatial learning and memory changes in AD rats.

Amyloid-β (Aβ) 1-42 was injected into lateral ventricle to establish an AD rat model. The rats were ...

AD rats showed a significant impairment in learning and memory compared to control rats. The results...

Our results showed that application of ELF-MF not only has improving effect on different cognitive disorder signs of AD animals, but also disrupts the processes of AD rat model formation.

Cite This Study
Akbarnejad Z, Esmaeilpour K, Shabani M, Asadi-Shekaari M, Saeedi-Goraghani M, Ahmadi M. (2018). Spatial memory recovery in Alzheimer's rat model by electromagnetic field exposure. Int J Neurosci. 128(8):691-696, 2018.
Show BibTeX
@article{z_2018_spatial_memory_recovery_in_591,
  author = {Akbarnejad Z and Esmaeilpour K and Shabani M and Asadi-Shekaari M and Saeedi-Goraghani M and Ahmadi M.},
  title = {Spatial memory recovery in Alzheimer's rat model by electromagnetic field exposure.},
  year = {2018},
  doi = {10.1080/00207454.2017.1411353},
  url = {https://www.tandfonline.com/doi/abs/10.1080/00207454.2017.1411353},
}

Quick Questions About This Study

Researchers injected rats with Alzheimer's-causing proteins and then exposed them to magnetic fields (50 Hz at 10 milliTesla) for 14 days. The magnetic field exposure significantly improved memory and learning abilities in the Alzheimer's rats, as measured by maze tests. This suggests that certain electromagnetic fields might help protect brain function in neurodegenerative diseases.