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Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

Cellular Effects

Effects of exposure to DAMPS and GSM signals on Ornithine Decarboxylase (ODC) activity: II. SH-SY5Y human neuroblastoma cells.

No Effects Found

Billaudel B, Taxile M, Poulletier de Gannes F, Ruffie G, Lagroye I, Veyret B. · 2009

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Cell phone radiation showed no effect on a growth-related enzyme in brain tumor cells, but this single endpoint doesn't rule out other cellular impacts.

Plain English Summary

Summary written for general audiences

Researchers exposed human brain tumor cells to cell phone radiation similar to DAMPS and GSM signals for up to 24 hours, then measured changes in an enzyme called ornithine decarboxylase (ODC) that's involved in cell growth. They found no changes in ODC activity regardless of the type of signal, exposure duration, or radiation intensity. This suggests that typical cell phone radiation levels don't affect this particular cellular process in brain cells.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 50 Hz - 217 Hz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 50 Hz - 217 HzCell phones~1 GHzWiFi2.4 GHz5G mm28 GHzLogarithmic scale

The study examined exposure from: 50 Hz-modulated DAMPS-835 or 217 Hz-modulated GSM-1800 Duration: 8 or 24 hours

Study Details

we extended this study to human neuroblastoma cells (SH-SY5Y), using well-defined waveguide systems to imitate exposure to radiofrequency radiation (RFR): Digital Advanced Mobile Phone System (DAMPS) or Global System for Mobile communications (GSM) signals emitted by mobile phones.

Human neuroblastoma cells (SH-SY5Y) were exposed at various Specific Absorption Rates (SAR) to DAMPS...

SH-SY5Y cells were incubated for 20 hours, and were blindly exposed to 50 Hz-modulated DAMPS-835 or ...

This work did not show a significant effect of mobile phone RFR exposure on ODC activity in neuroblastoma cells (SH-SY5Y).

Cite This Study
Billaudel B, Taxile M, Poulletier de Gannes F, Ruffie G, Lagroye I, Veyret B. (2009). Effects of exposure to DAMPS and GSM signals on Ornithine Decarboxylase (ODC) activity: II. SH-SY5Y human neuroblastoma cells. Int J Radiat Biol. 85(6):519-522, 2009.
Show BibTeX
@article{b_2009_effects_of_exposure_to_2954,
  author = {Billaudel B and Taxile M and Poulletier de Gannes F and Ruffie G and Lagroye I and Veyret B.},
  title = {Effects of exposure to DAMPS and GSM signals on Ornithine Decarboxylase (ODC) activity: II. SH-SY5Y human neuroblastoma cells.},
  year = {2009},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/19440939/},
}
PubMed: 19440939

Cited By (8 papers)

Quick Questions About This Study

A 2009 study found no effects on brain cell growth when human neuroblastoma cells were exposed to DAMPS and GSM cell phone radiation for up to 24 hours. The research measured ornithine decarboxylase activity, an enzyme involved in cell growth, and detected no changes regardless of signal type or exposure duration.
Research on GSM-1800 radiation exposure to human brain cells showed no cellular damage to a key growth enzyme called ornithine decarboxylase. The 2009 study exposed neuroblastoma cells to typical cell phone radiation levels for 8-24 hours and found no alterations in normal cellular processes.
A controlled study found no harmful effects when human neuroblastoma cells were exposed to DAMPS-835 radiation. Researchers measured ornithine decarboxylase enzyme activity, which regulates cell growth, and detected no changes after exposures lasting up to 24 hours at various radiation intensities.
Mobile phone radiation did not impact ornithine decarboxylase, a crucial brain enzyme involved in cell growth and division. A 2009 study exposed human brain tumor cells to both DAMPS and GSM signals and found no alterations in enzyme activity regardless of exposure duration or intensity.
Research on 1800 MHz GSM radiation found no effects on brain cell function when measured through ornithine decarboxylase enzyme activity. The study exposed human neuroblastoma cells to this frequency for up to 24 hours and detected no changes in cellular processes involved in growth and metabolism.