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Cellular Effects

Effects of exposure to DAMPS and GSM signals on ornithine decarboxylase (ODC) activity: I. L-929 mouse fibroblasts.

No Effects Found

Billaudel B, Taxile M, Ruffie G, Veyret B, Lagroye I. · 2009

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Cell phone signals showed no effect on a cancer-related enzyme in mouse cells, even at exposure levels exceeding safety limits.

Plain English Summary

Summary written for general audiences

Researchers exposed mouse cells to cell phone signals (DAMPS and GSM) for one hour to see if it would increase activity of ornithine decarboxylase (ODC), an enzyme linked to cell growth and potentially cancer development. They found no significant changes in ODC activity at exposure levels of 2.5 and 6 W/kg, contradicting some earlier studies that reported increased enzyme activity. This suggests that under controlled temperature conditions, these specific cell phone signals may not trigger this particular cellular response.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 50 Hz - 217 Hz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 50 Hz - 217 HzCell phones~1 GHzWiFi2.4 GHz5G mm28 GHzLogarithmic scale

The study examined exposure from: 50 Hz-modulated DAMPS-835, and 217 Hz modulated GSM-900 (wire-patch antenna) or GSM-1800 (waveguides) Duration: 1 hour

Study Details

The aim of this study is to investigate Effects of exposure to DAMPS and GSM signals on ornithine decarboxylase (ODC) activity: I. L-929 mouse fibroblasts.

Murine L-929 fibroblasts were exposed at various Specific Absorption rates (SAR) to (DAMPS) or Globa...

ODC activity in live L-929 cells showed no significant alteration after exposure at an SAR of 2.5 W/...

We conclude that under our exposure conditions, DAMPS-835 and GSM signals have no influence on ODC activity in L-929 cells.

Cite This Study
Billaudel B, Taxile M, Ruffie G, Veyret B, Lagroye I. (2009). Effects of exposure to DAMPS and GSM signals on ornithine decarboxylase (ODC) activity: I. L-929 mouse fibroblasts. Int J Radiat Biol. 85(6):510-518, 2009.
Show BibTeX
@article{b_2009_effects_of_exposure_to_2955,
  author = {Billaudel B and Taxile M and Ruffie G and Veyret B and Lagroye I.},
  title = {Effects of exposure to DAMPS and GSM signals on ornithine decarboxylase (ODC) activity: I. L-929 mouse fibroblasts.},
  year = {2009},
  doi = {10.1080/09553000902883760},
  url = {https://www.tandfonline.com/doi/abs/10.1080/09553000902883760},
}
DOI: 10.1080/09553000902883760

Cited By (9 papers)

Quick Questions About This Study

No, DAMPS-835 cell phone signals do not affect ornithine decarboxylase (ODC) enzyme activity in mouse cells. A 2009 study exposed L-929 cells to DAMPS signals for one hour at 2.5 and 6 W/kg and found no significant changes in ODC activity, contradicting some earlier research.
GSM-900 and GSM-1800 signals do not increase ornithine decarboxylase activity, an enzyme linked to cell growth and cancer development. Researchers found no significant changes in ODC activity when mouse fibroblast cells were exposed to these specific GSM frequencies under controlled conditions.
Mouse L-929 cells showed no significant changes in ornithine decarboxylase enzyme activity when exposed to 6 W/kg cell phone radiation for one hour. The study used active cooling fans to maintain normal cell temperature (37°C) during exposure to prevent heating effects.
Yes, temperature-controlled studies may show different results than earlier research. This 2009 study used careful temperature regulation and found no effects on ODC enzyme activity, while some previous studies without proper temperature control reported increased enzyme activity from cell phone radiation.
One hour exposure to 50 Hz-modulated DAMPS or 217 Hz-modulated GSM signals does not affect ornithine decarboxylase enzyme activity in mouse cells. The study tested multiple exposure setups including TEM cells and waveguides, finding no significant cellular enzyme changes.