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Effects of 900 MHz GSM Wireless Communication Signals on DMBA-Induced Mammary Tumors in Rats.

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Yu D, Shen Y, Kuster N, Fu Y, Chiang H. · 2006

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The study found no evidence that GSM microwave exposure promotes mammary tumor development in rats.

Plain English Summary

Summary written for general audiences

No significant differences in overall mammary tumor incidence, latency, multiplicity, or size were observed between microwave-exposed and sham-exposed groups. A tendency for reduced adenocarcinoma incidence at 0.44 W/kg and increased incidence at 4.0 W/kg did not reach statistical significance. Cage control rats had higher body weight, higher tumor incidence, and shorter tumor latency than sham- and microwave-exposed groups.

Why This Matters

The study aimed to investigate whether 900 MHz GSM wireless communication signals enhance mammary tumor development and growth induced by low-dose DMBA. Body weight did not differ significantly between sham- and GSM microwave-exposed groups. All mammary glands were examined histologically after the 26-week exposure period.

Exposure Details

SAR
4.0, 1.33, 0.44 and 0 W/kg
Source/Device
900 MHz
Exposure Duration
4 h/day, 5 days/week for 26 weeks.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kg
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

The purpose of the study was to investigate whether exposure to 900 MHz GSM wireless communication signals enhances mammary tumor development and growth induced by low-dose DMBA.

Five hundred female Sprague-Dawley rats were treated with a single dose of 35 mg/kg DMBA and then di...

There were no statistically significant differences in body weight between sham- and GSM microwave-e...

In the present study there were significant differences between the cage controls and the experimental groups (sham and exposure). Body weight and mammary tumor (malignant plus benign) incidence in the cage control group were significantly higher than in the sham- and GSM microwave-exposed groups. The latency to the mammary tumor onset was significantly shorter in the cage control group than in the other groups.

Cite This Study
Yu D, Shen Y, Kuster N, Fu Y, Chiang H. (2006). Effects of 900 MHz GSM Wireless Communication Signals on DMBA-Induced Mammary Tumors in Rats. Radiat Res. 165(2):174-180, 2006.
Show BibTeX
@article{d_2006_effects_of_900_mhz_1454,
  author = {Yu D and Shen Y and Kuster N and Fu Y and Chiang H.},
  title = {Effects of 900 MHz GSM Wireless Communication Signals on DMBA-Induced Mammary Tumors in Rats.},
  year = {2006},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/16435916/},
}

Cited By (29 papers)

Quick Questions About This Study

The purpose was to investigate whether exposure to 900 MHz GSM wireless communication signals enhances mammary tumor development and growth induced by low-dose DMBA.
Rats were exposed to 900 MHz GSM signals at SARs of 4.0, 1.33, 0.44, and 0 W/kg for 4 hours per day, 5 days per week for 26 weeks.
No significant differences in overall mammary tumor incidence, latency, multiplicity, or size were observed between microwave-exposed and sham-exposed groups.
There was a tendency for reduced adenocarcinoma incidence at 0.44 W/kg and increased incidence at 4.0 W/kg, but neither trend was statistically significant.
Cage control rats had significantly higher body weight, higher mammary tumor incidence, and shorter tumor latency than sham- and microwave-exposed groups.