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Effect of 835 MHz radiofrequency radiation exposure on calcium binding proteins in the hippocampus of the mouse brain

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Maskey D, Kim M, Aryal B, Pradhan J, Choi IY, Park KS, Son T, Hong SY, Kim SB, Kim HG, Kim MJ. · 2010

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One month of cell phone frequency exposure caused nearly complete loss of memory-critical brain cells in mice at radiation levels near current safety limits.

Plain English Summary

Summary written for general audiences

Researchers exposed mice to cell phone radiation (835 MHz) for one month and found almost complete loss of brain cells in the hippocampus, the region responsible for memory and learning. This suggests cell phone radiation may disrupt brain function and potentially affect memory formation.

Why This Matters

This study reveals concerning evidence that cell phone radiation can cause structural damage to critical brain regions involved in memory formation. The 835 MHz frequency used is very close to frequencies used by modern cellular networks, and the exposure levels (1.6-4.0 W/kg SAR) bracket the 2.0 W/kg safety limit set by the FCC. What makes this research particularly significant is the finding of actual cell loss in the hippocampus after one month of daily exposure. The hippocampus is essential for forming new memories and spatial navigation, and pyramidal cell loss in this region is associated with cognitive decline and memory disorders. While this was an animal study, the biological mechanisms involved - disruption of calcium homeostasis in neurons - are fundamental processes shared across mammalian species, making these findings relevant to human health concerns about long-term wireless device use.

Exposure Details

SAR
4, 1.6 W/kg
Source/Device
835 MHz
Exposure Duration
1 month

Exposure Context

This study used 4, 1.6 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 4, 1.6 W/kgExtreme Concern0.1 W/kgFCC Limit1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 1x higher than this exposure level

Study Details

To study the effect of 835 MHz radiofrequency radiation exposure on calcium binding proteins in the hippocampus of the mouse brain.

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Cite This Study
Maskey D, Kim M, Aryal B, Pradhan J, Choi IY, Park KS, Son T, Hong SY, Kim SB, Kim HG, Kim MJ. (2010). Effect of 835 MHz radiofrequency radiation exposure on calcium binding proteins in the hippocampus of the mouse brain Brain Res.1313:232-241, 2010.
Show BibTeX
@article{d_2010_effect_of_835_mhz_1187,
  author = {Maskey D and Kim M and Aryal B and Pradhan J and Choi IY and Park KS and Son T and Hong SY and Kim SB and Kim HG and Kim MJ. },
  title = {Effect of 835 MHz radiofrequency radiation exposure on calcium binding proteins in the hippocampus of the mouse brain},
  year = {2010},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S0006899309025980},
}

Quick Questions About This Study

Researchers exposed mice to cell phone radiation (835 MHz) for one month and found almost complete loss of brain cells in the hippocampus, the region responsible for memory and learning. This suggests cell phone radiation may disrupt brain function and potentially affect memory formation.