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Effect of a static magnetic fields and fluoride ions on the antioxidant defense system of mice fibroblasts.

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Kurzeja E, Synowiec-Wojtarowicz A, Stec M, Glinka M, Gawron S, Pawłowska-Góral K · 2013

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Static magnetic fields reduced oxidative stress caused by fluoride ions in fibroblasts and normalized antioxidant enzyme activity.

Plain English Summary

Summary written for general audiences

Researchers studied the potential relationship between static magnetic field exposure and the antioxidant system of fibroblasts cultured with fluoride ions. Three chambers with static magnetic fields of different intensities (0.4, 0.6, and 0.7 T) were used, and fluoride ions were added at a concentration of 0.12 mM. Static magnetic fields were found to reduce the oxidative stress caused by fluoride ions and to normalize the activities of antioxidant enzymes including superoxide dismutase, glutathione peroxidase, and catalase. The results also suggest that exposure to fluoride and a static magnetic field improves the tolerance of cells to the oxidative stress induced by fluoride ions.

Why This Matters

The study used fibroblasts cultured with fluoride ions and exposed them to static magnetic fields at three different intensities. Fluoride ions were used at a concentration of 0.12 mM, a level that did not cause the precipitation of calcium or magnesium. Static magnetic fields normalized the activities of antioxidant enzymes, including superoxide dismutase, glutathione peroxidase, and catalase. Static magnetic fields also modified the energy state of fibroblasts, causing an increase in ATP concentration and a decrease in MDA concentration.

Exposure Details

Magnetic Field
400, 600, 700 mT

Exposure Context

This study used 400, 600, 700 mT for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 400, 600, 700 mTExtreme Concern - 5 mGFCC Limit - 2,000 mGEffects observed in the Extreme Concern range (Building Biology)This level is 2,000 times the FCC limit

Study Details

The aim of this work was to determine the potential relationship between magnetic field exposure to, and the antioxidant system of, fibroblasts cultured with fluoride ions.

Three chambers with static magnetic fields of different intensities (0.4, 0.6, and 0.7 T) were used ...

The results of this study show that static magnetic fields reduce the oxidative stress caused by flu...

These results suggest that exposure to fluoride and an SMF improves the tolerance of cells to the oxidative stress induced by fluoride ions

Cite This Study
Kurzeja E, Synowiec-Wojtarowicz A, Stec M, Glinka M, Gawron S, Pawłowska-Góral K (2013). Effect of a static magnetic fields and fluoride ions on the antioxidant defense system of mice fibroblasts. Int J Mol Sci.14(7):15017-15028, 2013.
Show BibTeX
@article{e_2013_effect_of_a_static_403,
  author = {Kurzeja E and Synowiec-Wojtarowicz A and Stec M and Glinka M and Gawron S and Pawłowska-Góral K},
  title = {Effect of a static magnetic fields and fluoride ions on the antioxidant defense system of mice fibroblasts.},
  year = {2013},
  
  url = {https://www.mdpi.com/1422-0067/14/7/15017},
}

Quick Questions About This Study

The study used fibroblasts cultured with fluoride ions.
Three chambers with static magnetic fields of 0.4, 0.6, and 0.7 T were used.
Static magnetic fields normalized the activities of antioxidant enzymes, including superoxide dismutase, glutathione peroxidase, and catalase.
Static magnetic fields caused an increase in ATP concentration and a decrease in MDA concentration in fibroblasts.
The results suggest that exposure to fluoride and a static magnetic field improves the tolerance of cells to the oxidative stress induced by fluoride ions.