Static magnetic field exposure-induced oxidative response and caspase-independent apoptosis in rat liver: effect of selenium and vitamin E supplementations.
Ghodbane S, Ammari M, Lahbib A, Sakly M, Abdelmelek H. · 2015
View Original AbstractStrong static magnetic fields caused liver cell death in rats that antioxidants couldn't fully prevent, suggesting complex biological damage pathways.
Plain English Summary
Researchers exposed rats to strong static magnetic fields (128 mT) for one hour daily over five days and found significant liver damage, including increased oxidative stress and cell death through a process called apoptosis. The brain showed no similar damage, suggesting the liver is more vulnerable to magnetic field exposure. Even antioxidant supplements like selenium and vitamin E couldn't fully protect against the liver cell death.
Why This Matters
This study demonstrates that static magnetic fields can cause measurable biological damage at exposure levels far higher than typical consumer electronics but within the range of some medical MRI machines and industrial equipment. The 128 mT exposure used here is roughly 2,500 times stronger than Earth's magnetic field and significantly higher than most everyday sources. What's particularly concerning is that antioxidant supplementation provided only partial protection, suggesting the cellular damage pathways may be more complex than simple oxidative stress. The liver-specific effects also indicate that different organs may have varying susceptibility to magnetic field exposure, which has important implications for occupational safety standards and medical device protocols.
Exposure Details
- Magnetic Field
- 128 mG
- Exposure Duration
- 1 h/day during five consecutive days
Exposure Context
This study used 128 mG for magnetic fields:
- 6.4Mx above the Building Biology guideline of 0.2 mG
- 1.3Mx above the BioInitiative Report recommendation of 1 mG
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
In the present study, we investigated the implication of oxidative stress and apoptosis under static magnetic field (SMF) in the brain and liver.Moreover, we estimated the protective role of selenium and vitamin E in rat tissues against disorders induced by SMF.
Exposure of rats to SMF (128 mT, 1 h/day during five consecutive days) increased the activity of cat...
Show BibTeX
@article{s_2015_static_magnetic_field_exposureinduced_373,
author = {Ghodbane S and Ammari M and Lahbib A and Sakly M and Abdelmelek H.},
title = {Static magnetic field exposure-induced oxidative response and caspase-independent apoptosis in rat liver: effect of selenium and vitamin E supplementations.},
year = {2015},
doi = {10.1007/s11356-015-4802-2},
url = {https://link.springer.com/article/10.1007/s11356-015-4802-2},
}