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Impact of Static Magnetic Field on the Antioxidant Defence System of Mice Fibroblasts.

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Glinka M, Gawron S, Sieroń A, Pawłowska-Góral K, Cieślar G, Sieroń K. · 2018

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Static magnetic fields did not cause oxidative stress in mouse fibroblasts and may show slight antioxidizing activity.

Plain English Summary

Summary written for general audiences

Researchers assessed the impact of static magnetic fields of different intensities on redox homeostasis in cultures of fibroblasts. Six chambers with field flux densities varying from 0.1 to 0.7 T were used in the research. ATP concentration and the generation of malondialdehyde, a marker of oxidative stress, remained stable, while the activity of superoxide dismutase and glutathione peroxidase decreased.

Why This Matters

The study measured several markers related to oxidative stress, including the antioxidant enzymes superoxide dismutase and glutathione peroxidase, as well as ATP and malondialdehyde. Malondialdehyde is used as a marker of oxidative stress, and its generation was stable across exposures. The results suggest the fields may show slight antioxidizing activity.

Exposure Details

Magnetic Field
100 to 700 mT

Exposure Context

This study used 100 to 700 mT for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 100 to 700 mTExtreme Concern - 5 mGFCC Limit - 2,000 mGEffects observed in the Extreme Concern range (Building Biology)This level is 500 times the FCC limit

Study Details

The goal of current work was to assess the impact of static magnetic field of different intensities on redox homeostasis in cultures of fibroblasts.

During the research we used 6 chambers, designed exclusively by us, with different values of field f...

We have noted the decrease in the activity of superoxide dismutase (SOD) and glutathione peroxidase ...

Results of research suggest that static magnetic fields generated by permanent magnets do not cause oxidative stress in investigated fibroblasts and that they may show slight antioxidizing activity.

Cite This Study
Glinka M, Gawron S, Sieroń A, Pawłowska-Góral K, Cieślar G, Sieroń K. (2018). Impact of Static Magnetic Field on the Antioxidant Defence System of Mice Fibroblasts. Biomed Res Int. 2018:5053608, 2018.
Show BibTeX
@article{m_2018_impact_of_static_magnetic_377,
  author = {Glinka M and Gawron S and Sieroń A and Pawłowska-Góral K and Cieślar G and Sieroń K.},
  title = {Impact of Static Magnetic Field on the Antioxidant Defence System of Mice Fibroblasts.},
  year = {2018},
  
  url = {https://www.hindawi.com/journals/bmri/2018/5053608/},
}

Quick Questions About This Study

The results suggest that static magnetic fields generated by permanent magnets do not cause oxidative stress in the investigated fibroblasts.
A decrease in the activity of superoxide dismutase and glutathione peroxidase was noted.
Six chambers with field flux density values varying from 0.1 to 0.7 T were used.
The static magnetic fields did not modify the energy state of fibroblasts, and ATP concentration was stable.