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The effects of Gum Arabic, curcumin (Curcuma longa) and Garcinia kola on the rat hippocampus after electromagnetic field exposure: A stereological and histological study

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Elamin AAE, Deniz OG, Kaplan S · 2021

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Exposure to EMF caused a significant decrease in CA pyramidal neurons, curcumin and Garcinia kola provided significant protection, and gum arabic showed no protective effect.

Plain English Summary

Summary written for general audiences

Fifty-four 12-week-old male Wistar albino rats were randomly divided into nine groups of six, and the EMF+Cur, EMF+GK, EMF+GA, and EMF groups were exposed to 900MHz EMF for one hour a day for 28 days. Stereological analysis showed a significant decrease in the total number of CA pyramidal neurons in the EMF group compared with control and sham groups. The EMF group also had significantly higher catalase and superoxide dismutase activities than controls.

Why This Matters

The number of pyramidal neurons was estimated using the optical fractionator technique, and histopathological changes were examined with light and electron microscopy. The control, curcumin, Garcinia kola, and gum arabic groups were not exposed to EMF, while the sham group was kept in the exposure system without EMF.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study.

Cite This Study
Elamin AAE, Deniz OG, Kaplan S (2021). The effects of Gum Arabic, curcumin (Curcuma longa) and Garcinia kola on the rat hippocampus after electromagnetic field exposure: A stereological and histological study.
Show BibTeX
@article{elamin_aae_deniz_og_kaplan_s_ce2360,
  author = {Elamin AAE and Deniz OG and Kaplan S},
  title = {The effects of Gum Arabic, curcumin (Curcuma longa) and Garcinia kola on the rat hippocampus after electromagnetic field exposure: A stereological and histological study},
  year = {2021},
  doi = {10.1016/j.jchemneu.2021.102060},
  
}

Quick Questions About This Study

The EMF+Cur, EMF+GK, EMF+GA, and EMF groups were exposed to 900MHz EMF for one hour a day for 28 days.
Stereological analysis revealed a significant decrease in the total number of CA pyramidal neurons in the EMF group compared with control and sham groups.
Cur and GK were observed to provide significant protection in the EMF+Cur and EMF+GK groups compared to the EMF group.
No significant difference was observed between the EMF+GA group and the EMF group.
The EMF group showed significantly higher catalase and superoxide dismutase activities than the control group.