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Antioxidants alleviate electric field-induced effects on lung tissue based on assays of heme oxygenase-1, protein carbonyl content, malondialdehyde, nitric oxide, and hydroxyproline.

No Effects Found

Güler G, Türközer Z, Ozgur E, Seyhan N. · 2009

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Electric fields 1,000 times stronger than typical environmental levels caused minimal lung tissue damage in this laboratory study.

Plain English Summary

Summary written for general audiences

Researchers exposed lung tissue to extremely strong electric fields (12,000 volts per meter) for 8 hours daily over 7 days to test whether antioxidants could prevent damage. They found only minor increases in one marker of cellular damage (protein carbonyl), while other damage indicators remained unchanged. The study suggests that at these exposure levels, electric fields cause minimal lung tissue damage that antioxidants may help prevent.

Study Details

In order to test whether antioxidants have beneficiary effects on electric field induced damage, we determined the pulmonary levels of heme oxygenase-1 (HO-1), protein carbonyl content (PCO), malondialdehyde (MDA), nitric oxide (NO) and hydroxyproline (HP) under extremely low frequency (ELF) electric (E) field exposure (50 Hz, 12 kV/m, 7 days/for 8 h/day).

While PCO levels significantly increased (p < 0.05), insignificant changes (p > 0.05) were observed ...

Cite This Study
Güler G, Türközer Z, Ozgur E, Seyhan N. (2009). Antioxidants alleviate electric field-induced effects on lung tissue based on assays of heme oxygenase-1, protein carbonyl content, malondialdehyde, nitric oxide, and hydroxyproline. Sci Total Environ. 407(4):1326-1332, 2009b.
Show BibTeX
@article{g_2009_antioxidants_alleviate_electric_fieldinduced_2846,
  author = {Güler G and Türközer Z and Ozgur E and Seyhan N.},
  title = {Antioxidants alleviate electric field-induced effects on lung tissue based on assays of heme oxygenase-1, protein carbonyl content, malondialdehyde, nitric oxide, and hydroxyproline. },
  year = {2009},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S0048969708010772},
}

Quick Questions About This Study

Researchers exposed lung tissue to extremely strong electric fields (12,000 volts per meter) for 8 hours daily over 7 days to test whether antioxidants could prevent damage. They found only minor increases in one marker of cellular damage (protein carbonyl), while other damage indicators remained unchanged. The study suggests that at these exposure levels, electric fields cause minimal lung tissue damage that antioxidants may help prevent.