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Effects of exposure to 50 Hz electric field at different strengths on oxidative stress and antioxidant enzyme activities in the brain tissue of guinea pigs.

No Effects Found

Türközer Z, Güler G, Seyhan N. · 2008

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Electric fields up to 5,000 V/m showed no significant oxidative stress in guinea pig brains after 24 hours of exposure.

Plain English Summary

Summary written for general audiences

Researchers exposed guinea pigs to 50 Hz electric fields at various strengths (from 2,000 to 5,000 volts per meter) for 8 hours daily over three days, then measured markers of oxidative stress in brain tissue. The study found no statistically significant changes in cellular damage markers or antioxidant enzyme activity, though some non-significant trends were observed. This suggests that short-term exposure to these electric field levels may not cause measurable oxidative stress in brain tissue.

Study Details

The aim of this study was to evaluate the possible effects of varied exposure to 50 Hz extremely low frequency (ELF) electric field (EF) on the lipid peroxidation levels and antioxidant enzyme activities in the brain homogenates of guinea pigs. Subjects were exposed to 2 kV/m, 2.5 kV/m, 3 kV/m, 3.5 kV/m, 4 kV/m, 4.5 kV/m and 5 kV/m electric fields for three days, 8 h a day in both vertical and horizontal directions.

Malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-P...

Although the study showed several positive but non-significant findings (p > 0.05), we did not find ...

The present study observed effects of 50 Hz EF exposure on lipid peroxidation levels and antioxidant defense mechanisms but these were not statistically significant at the 95% confidence level. Further research on the effects ELF-EF exposure on lipid peroxidation levels and antioxidant defence mechanisms are warranted.

Cite This Study
Türközer Z, Güler G, Seyhan N. (2008). Effects of exposure to 50 Hz electric field at different strengths on oxidative stress and antioxidant enzyme activities in the brain tissue of guinea pigs. Int J Radiat Biol. 84(7):581-590, 2008.
Show BibTeX
@article{z_2008_effects_of_exposure_to_2832,
  author = {Türközer Z and Güler G and Seyhan N.},
  title = {Effects of exposure to 50 Hz electric field at different strengths on oxidative stress and antioxidant enzyme activities in the brain tissue of guinea pigs.},
  year = {2008},
  doi = {10.1080/09553000802203606},
  url = {https://www.tandfonline.com/doi/abs/10.1080/09553000802203606},
}

Quick Questions About This Study

Researchers exposed guinea pigs to 50 Hz electric fields at various strengths (from 2,000 to 5,000 volts per meter) for 8 hours daily over three days, then measured markers of oxidative stress in brain tissue. The study found no statistically significant changes in cellular damage markers or antioxidant enzyme activity, though some non-significant trends were observed. This suggests that short-term exposure to these electric field levels may not cause measurable oxidative stress in brain tissue.