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Neurodegenerative changes and apoptosis induced by intrauterine and extrauterine exposure of radiofrequency radiation

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Güler G, Ozgur E, Keles H, Tomruk A, Vural SA, Seyhan N · 2016

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Combined intrauterine and extrauterine exposure to GSM-modulated radiofrequency radiation increased oxidative DNA damage in rabbit brains, but no apoptosis was detected.

Plain English Summary

Summary written for general audiences

Researchers exposed newborn rabbits to GSM-modulated 1800 MHz radiation before and after birth and measured oxidative DNA damage, lipid peroxidation, histopathology, and apoptosis in brain tissue. Oxidative DNA damage measured as 8-OHdG increased in rabbits exposed during both intrauterine and extrauterine periods compared to unexposed rabbits and those exposed only after birth. Lipid peroxidation measured as MDA rose only in males with intrauterine exposure, while females showed no difference across exposure groups. Mild neuronal necrobiosis appeared in intrauterine-exposed females and extrauterine-exposed males; gliosis was mildly positive in intrauterine-only and combined-exposure groups, but no apoptosis was detected in any group.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 1800 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 1800 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study.

Cite This Study
Güler G, Ozgur E, Keles H, Tomruk A, Vural SA, Seyhan N (2016). Neurodegenerative changes and apoptosis induced by intrauterine and extrauterine exposure of radiofrequency radiation.
Show BibTeX
@article{gler_g_ozgur_e_keles_h_tomruk_a_vural_sa_seyhan_n_ce2394,
  author = {Güler G and Ozgur E and Keles H and Tomruk A and Vural SA and Seyhan N},
  title = {Neurodegenerative changes and apoptosis induced by intrauterine and extrauterine exposure of radiofrequency radiation},
  year = {2016},
  doi = {10.1016/j.jchemneu.2015.10.006},
  
}

Quick Questions About This Study

The study used GSM-modulated 1800 MHz radiofrequency radiation and exposed rabbits during intrauterine and extrauterine periods.
8-OHdG levels increased in both male and female rabbits exposed during both intrauterine and extrauterine periods compared to unexposed and postnatally exposed groups.
MDA levels increased significantly only in male infants with intrauterine exposure, while no differences were found among female groups.
Mild neuronal necrobiosis was observed in intrauterine-exposed females and extrauterine-exposed males, and gliosis was mildly positive in intrauterine-only and combined-exposure groups.
No apoptotic changes were detected by TUNEL staining in the brain tissues of all exposure groups.