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Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

Brain & Nervous System

1950 MHz IMT-2000 field does not activate microglial cells in vitro.

No Effects Found

Hirose H, Sasaki A, Ishii N, Sekijima M, Iyama T, Nojima T, Ugawa Y. · 2010

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Two-hour exposure to 3G cell phone radiation did not activate brain immune cells at power levels up to 2.0 W/kg.

Plain English Summary

Summary written for general audiences

Japanese researchers exposed rat brain immune cells called microglia to 1950 MHz cell phone radiation for 2 hours at various power levels, then monitored the cells for signs of activation or inflammation. They found no significant differences between exposed and unexposed cells in terms of immune markers or inflammatory proteins. This suggests that short-term exposure to 3G cell phone frequencies at typical power levels does not trigger immune responses in brain cells.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 1.95 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 1.95 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

The study examined exposure from: 1950 MHz Duration: 2 hours

Study Details

To examine any biological effects on the central nervous system (CNS) induced by 1950 MHz modulation signals, which are controlled by the International Mobile Telecommunication-2000 (IMT-2000) cellular system, we investigated the effect of RF fields on microglial cells in the brain.

We assessed functional changes in microglial cells by examining changes in immune reaction-related m...

Results showed that the percentage of cells positive for major histocompatibility complex (MHC) clas...

These findings suggest that exposure to RF fields up to 2 W/kg does not activate microglial cells in vitro.

Cite This Study
Hirose H, Sasaki A, Ishii N, Sekijima M, Iyama T, Nojima T, Ugawa Y. (2010). 1950 MHz IMT-2000 field does not activate microglial cells in vitro. Bioelectromagnetics.31(2):104-112, 2010.
Show BibTeX
@article{h_2010_1950_mhz_imt2000_field_3088,
  author = {Hirose H and Sasaki A and Ishii N and Sekijima M and Iyama T and Nojima T and Ugawa Y.},
  title = {1950 MHz IMT-2000 field does not activate microglial cells in vitro.},
  year = {2010},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/19650078/},
}
PubMed: 19650078

Cited By (32 papers)

Quick Questions About This Study

No, Japanese research found that 1950 MHz 3G radiation does not activate microglial immune cells in brain tissue. Rat brain cells exposed to typical cell phone power levels for 2 hours showed no immune activation markers or inflammatory protein changes compared to unexposed cells.
Research indicates W-CDMA signals do not cause brain inflammation. A 2010 study exposed rat brain immune cells to 1950 MHz W-CDMA radiation and found no increase in inflammatory proteins like TNF-alpha, IL-1beta, or IL-6 compared to control groups.
Studies suggest 2 W/kg SAR exposure does not harm brain immune cells. Research testing various power levels up to 2 W/kg found no activation of microglial cells or changes in immune markers after 2-hour exposures to 1950 MHz radiation.
No, 3G cell phones do not trigger MHC class II immune responses in brain tissue. Laboratory testing showed similar percentages of MHC class II positive microglial cells in both radiation-exposed and control groups, indicating no immune system activation.
Research suggests 1950 MHz radiation does not affect brain immune cells even after 2-hour exposures. Japanese scientists found no significant changes in microglial cell activation or inflammatory markers following extended exposure to typical 3G power levels.