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Combined effects of 60 Hz electromagnetic field exposure with various stress factors on cellular transformation in NIH3T3 cells.

No Effects Found

Lee HJ, Jin YB, Lee JS, Choi JI, Lee JW, Myung SH, Lee YS. · 2012

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This study found no cancer-promoting effects from 60 Hz magnetic fields at levels much higher than typical household exposure.

Plain English Summary

Summary written for general audiences

Researchers exposed mouse cells to 60 Hz magnetic fields (the type from power lines) to see if this could trigger cellular transformation into cancer-like cells. They tested the magnetic field alone and combined with known cancer-causing agents like radiation. The study found no evidence that the magnetic field exposure caused cell transformation or enhanced the cancer-causing effects of other agents.

Study Details

Here, the carcinogenic potential of ELF-MF exposure alone and in combination with various stress factors was investigated in NIH3T3 mouse fibroblasts using an in vitro cellular transformation assay.

NIH3T3 cells were exposed to a 60 Hz ELF-MF (1 mT) alone or in combination with ionizing radiation (...

A 4 h exposure of NIH3T3 cells to ELF-MF alone produced no cell transformation. Moreover, ELF exposure did not influence the transformation activity of IR, H2O2, or activated c-Myc in our in vitro assay system, suggesting that 1 mT ELF-MF did not affect any additive or synergistic transformation activities in combination with stress factors such as IR, H2O2, or activated c-Myc in NIH3T3 cells.

Cite This Study
Lee HJ, Jin YB, Lee JS, Choi JI, Lee JW, Myung SH, Lee YS. (2012). Combined effects of 60 Hz electromagnetic field exposure with various stress factors on cellular transformation in NIH3T3 cells. Bioelectromagnetics. 33(3):207-214, 2012.
Show BibTeX
@article{hj_2012_combined_effects_of_60_2853,
  author = {Lee HJ and Jin YB and Lee JS and Choi JI and Lee JW and Myung SH and Lee YS.},
  title = {Combined effects of 60 Hz electromagnetic field exposure with various stress factors on cellular transformation in NIH3T3 cells.},
  year = {2012},
  doi = {10.1002/bem.20700},
  url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/bem.20700},
}

Quick Questions About This Study

Researchers exposed mouse cells to 60 Hz magnetic fields (the type from power lines) to see if this could trigger cellular transformation into cancer-like cells. They tested the magnetic field alone and combined with known cancer-causing agents like radiation. The study found no evidence that the magnetic field exposure caused cell transformation or enhanced the cancer-causing effects of other agents.