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Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

Cellular Effects

Exposure to GSM RF fields does not affect calcium homeostasis in human endothelial cells, rat pheocromocytoma cells or rat hippocampal neurons.

No Effects Found

O'Connor RP, Madison SD, Leveque P, Roderick HL, Bootman MD · 2010

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GSM cell phone radiation showed no effects on cellular calcium function at exposure levels up to and exceeding typical phone use.

Plain English Summary

Summary written for general audiences

Researchers exposed three types of cells (including human blood vessel cells and brain cells) to 900 MHz cell phone radiation at various power levels to see if it affected calcium levels inside the cells. Calcium is crucial for cell function and communication. They found no changes in calcium activity, even at radiation levels higher than typical phone exposure, suggesting that GSM cell phone signals don't disrupt this fundamental cellular process.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

The study examined exposure from: 900 MHz GSM

Study Details

In the present study, we used a high-throughput imaging platform to monitor putative changes in cellular Ca2+ during exposure of cells to 900 MHz GSM fields of differing power (specific absorption rate 0.012–2 W/Kg), thus mimicking the type of radiation emitted by current mobile phone handsets.

Data from cells experiencing the 900 Mhz GSM fields were compared with data obtained from paired exp...

Our data indicate that 900 MHz GSM fields do not affect either basal Ca2+ homeostasis or provoked Ca...

We conclude that under the conditions employed in our experiments, and using a highly-sensitive assay, we could not detect any consequence of RF exposure.

Cite This Study
O'Connor RP, Madison SD, Leveque P, Roderick HL, Bootman MD (2010). Exposure to GSM RF fields does not affect calcium homeostasis in human endothelial cells, rat pheocromocytoma cells or rat hippocampal neurons. PLoS One. 5(7):e11828, 2010.
Show BibTeX
@article{rp_2010_exposure_to_gsm_rf_2789,
  author = {O'Connor RP and Madison SD and Leveque P and Roderick HL and Bootman MD},
  title = {Exposure to GSM RF fields does not affect calcium homeostasis in human endothelial cells, rat pheocromocytoma cells or rat hippocampal neurons. },
  year = {2010},
  
  url = {https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0011828},
}

Quick Questions About This Study

No, 900 MHz GSM radiation does not affect calcium levels in human endothelial cells. A 2010 study exposed human blood vessel cells to cell phone frequencies and found no changes in calcium activity, even at radiation levels higher than typical phone exposure.
Cell phone radiation does not disrupt calcium signals in rat hippocampal neurons. Researchers found no changes in calcium homeostasis in brain cells exposed to 900 MHz GSM fields, suggesting this fundamental cellular process remains unaffected by phone radiation.
GSM cell phone signals do not affect calcium levels in rat pheochromocytoma cells. The 2010 study by O'Connor and colleagues found no impact on calcium homeostasis in these nerve cells, even when exposed to field strengths exceeding typical phone use.
Calcium homeostasis is not disrupted by 900 MHz radiofrequency exposure. Using highly sensitive assays on three different cell types, researchers detected no consequences of RF exposure on either baseline calcium levels or calcium signaling responses in cells.
Highly sensitive calcium assays revealed no detectable effects from GSM radiation exposure. The study used advanced measurement techniques on human endothelial cells, rat brain neurons, and pheochromocytoma cells, finding no changes in cellular calcium activity at any tested power level.