Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

2-GHz band CW and W-CDMA modulated radiofrequency fields have no significant effect on cell proliferation and gene expression profile in human cells.

No Effects Found

Sekijima M, Takeda H, Yasunaga K, Sakuma N, Hirose H, Nojima T, Miyakoshi J. · 2010

View Original Abstract

Researchers found no significant effect on cell proliferation or gene expression in human cell lines exposed to 2.1425 GHz CW and W-CDMA fields at SARs up to 800 mW/kg for up to 96 hours.

Plain English Summary

Summary written for general audiences

The study examined cell proliferation and gene expression in three human cell lines after exposure to 2.1425 GHz continuous wave and W-CDMA modulated radiofrequency fields. Cells were exposed at specific absorption rates of 80, 250, or 800 mW/kg for up to 96 hours. No significant differences in cell growth or viability were found between exposed groups and sham controls, and less than 1% of genes showed altered expression.

Exposure Details

SAR: 0.08, 0.25, 0.8 W/kg
Source/Device: 2.1425 GHz
Exposure Duration: 96 h

Where This Falls on the Concern Scale

Study Details

We investigated the mechanisms by which radiofrequency (RF) fields exert their activity, and the changes in both cell proliferation and the gene expression profile in the human cell lines, A172 (glioblastoma), H4 (neuroglioma), and IMR-90 (fibroblasts from normal fetal lung) following exposure to 2.1425 GHz continuous wave (CW) and Wideband Code Division Multiple Access (W-CDMA) RF fields at three field levels.

During the incubation phase, cells were exposed at the specific absorption rates (SARs) of 80, 250, ...

No significant differences in cell growth or viability were observed between any test group exposed ...

These results suggest that RF exposure up to the limit of whole-body average SAR levels as specified in the ICNIRP guidelines is unlikely to elicit a general stress response in the tested cell lines under these conditions.

Cite This Study

Sekijima M, Takeda H, Yasunaga K, Sakuma N, Hirose H, Nojima T, Miyakoshi J. (2010). 2-GHz band CW and W-CDMA modulated radiofrequency fields have no significant effect on cell proliferation and gene expression profile in human cells. J Radiat Res. 51(3):277-284, 2010.

Show BibTeX

@article{m_2010_2ghz_band_cw_and_3389,
  author = {Sekijima M and Takeda H and Yasunaga K and Sakuma N and Hirose H and Nojima T and Miyakoshi J.},
  title = {2-GHz band CW and W-CDMA modulated radiofrequency fields have no significant effect on cell proliferation and gene expression profile in human cells.},
  year = {2010},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/20215713/},
}

PubMed: 20215713