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Chronic exposure to 50 Hz magnetic fields causes a significant weakening of antioxidant defence systems in aged rat brain.

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Falone S, Mirabilio A, Carbone MC, Zimmitti V, Di Loreto S, Mariggiò MA, Mancinelli R, Di Ilio C, Amicarelli F. · 2008

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Aging brains lose their ability to defend against magnetic field exposure, with older rats showing weakened antioxidant systems at everyday EMF levels.

Plain English Summary

Summary written for general audiences

Italian researchers exposed young and older rats to 50 Hz magnetic fields from power lines for 10 days. Young rats strengthened their brain's antioxidant defenses, but older rats experienced significant weakening of these protective systems, suggesting aging brains are more vulnerable to EMF damage.

Why This Matters

This study reveals a critical vulnerability that the EMF safety establishment has largely ignored: age matters when it comes to EMF exposure. The 0.1 mT magnetic field used here is well within levels you encounter daily from household wiring, appliances, and proximity to power lines. What makes this research particularly significant is its demonstration that the same EMF exposure that young organisms can adapt to actually overwhelms the defensive capabilities of aging brains.

The reality is that our current safety standards are based on acute effects in healthy adults, not the cumulative impact on aging populations who may be most at risk. This research adds to growing evidence that chronic, low-level EMF exposure may contribute to the oxidative stress underlying neurodegenerative diseases. While you can't avoid all magnetic field exposure, understanding that your vulnerability may increase with age underscores the importance of reducing unnecessary exposure where possible.

Exposure Details

Magnetic Field
0.1 mG
Source/Device
50 Hz
Exposure Duration
10 days

Exposure Context

This study used 0.1 mG for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 0.1 mGExtreme Concern5 mGFCC Limit2,000 mGEffects observed in the No Concern range (Building Biology)FCC limit is 20,000x higher than this exposure level

Study Details

The aim of this study was to establish whether the ageing process can increase susceptibility towards widely present ELF-MF-mediated pro-oxidative challenges.

To this end, female Sprague–Dawley rats were continuously exposed to a sinusoidal 50 Hz, 0.1 mT magn...

Our results indicated that ELF-MF exposure significantly affects anti-oxidative capability, both in ...

In conclusion, our data seem to suggest that the exposure to ELF-MFs may act as a risk factor for the occurrence of oxidative stress-based nervous system pathologies associated with ageing.

Cite This Study
Falone S, Mirabilio A, Carbone MC, Zimmitti V, Di Loreto S, Mariggiò MA, Mancinelli R, Di Ilio C, Amicarelli F. (2008). Chronic exposure to 50 Hz magnetic fields causes a significant weakening of antioxidant defence systems in aged rat brain. Int J Biochem Cell Biol. 40(12):2762-2770, 2008.
Show BibTeX
@article{s_2008_chronic_exposure_to_50_356,
  author = {Falone S and Mirabilio A and Carbone MC and Zimmitti V and Di Loreto S and Mariggiò MA and Mancinelli R and Di Ilio C and Amicarelli F.},
  title = {Chronic exposure to 50 Hz magnetic fields causes a significant weakening of antioxidant defence systems in aged rat brain.},
  year = {2008},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S1357272508002161},
}

Quick Questions About This Study

Italian researchers exposed young and older rats to 50 Hz magnetic fields from power lines for 10 days. Young rats strengthened their brain's antioxidant defenses, but older rats experienced significant weakening of these protective systems, suggesting aging brains are more vulnerable to EMF damage.