Effects of extremely low frequency electromagnetic fields on paraoxonase serum activity and lipid peroxidation metabolites in rat.
Seifirad S, Farzampour S, Nourbakhsh M, Amoli MM, Razzaghy-Azar M, Larijani B · 2014
View Original AbstractChronic power frequency EMF exposure disrupted antioxidant defenses and increased cellular damage in rats, with effects becoming irreversible over time.
Plain English Summary
Researchers exposed rats to 60 Hz electromagnetic fields (household electricity frequency) for single sessions or 14 days. Both exposures increased cellular damage markers, but chronic exposure caused potentially irreversible harm to the body's antioxidant defense systems that protect against cellular damage.
Why This Matters
This study adds important evidence to our understanding of how everyday power frequency EMFs affect cellular health. The researchers used 0.5 milliTesla magnetic fields, which is roughly 50 times stronger than typical home exposures but well within the range you might encounter near power lines or electrical equipment. What makes this research particularly significant is the clear demonstration that duration matters - while single exposures caused reversible changes, chronic exposure led to lasting disruption of the body's oxidative balance. The science demonstrates that our cells' protective antioxidant systems can be overwhelmed by sustained EMF exposure, potentially setting the stage for various health problems. This finding aligns with a growing body of research showing that EMFs can trigger oxidative stress, one of the fundamental mechanisms underlying many chronic diseases.
Exposure Details
- Magnetic Field
- 0.5 mG
- Source/Device
- 60 Hz
- Exposure Duration
- Fourteen days
Exposure Context
This study used 0.5 mG for magnetic fields:
- 25Kx above the Building Biology guideline of 0.2 mG
- 5Kx above the BioInitiative Report recommendation of 1 mG
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
This study was therefore undertaken to examine the effects of ELF-MF on paraoxonase (PON) activity, antioxidant capacity and lipid peroxidation metabolites. Effects of time on remodeling of antioxidant system were also investigated in this study.
Seventy five Wistar rats were randomly allocated into five groups as follows: 1) Sham exposure, 2) S...
Single ELF-MF exposure significantly increased lipid peroxidation (CD and MDA) and increased antioxi...
According to the results of this study, ELF-MF exposure could impair oxidant-antioxidant function and might increase oxidative stress and lipid peroxidation. Antioxidant capability was dependent on the duration and continuity of ELF-MF exposure.
Show BibTeX
@article{s_2014_effects_of_extremely_low_458,
author = {Seifirad S and Farzampour S and Nourbakhsh M and Amoli MM and Razzaghy-Azar M and Larijani B},
title = {Effects of extremely low frequency electromagnetic fields on paraoxonase serum activity and lipid peroxidation metabolites in rat.},
year = {2014},
doi = {10.1186/s40200-014-0085-2},
url = {https://link.springer.com/article/10.1186/s40200-014-0085-2},
}