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Long term and excessive use of 900 MHz radiofrequency radiation alter microrna expression in brain.

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Dasdag S, Akdag MZ, Erdal ME, Erdal N, Ay OI, Ay ME, Yilmaz SG, Tasdelen B, Yegin K. · 2014

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After a year of daily 900 MHz radiofrequency exposure, only one microRNA (rno-miR107) was decreased in rat brain tissue, while the others studied were unchanged.

Plain English Summary

Summary written for general audiences

Researchers exposed rats to 900 MHz radiofrequency radiation for 3 hours per day, 7 days a week, for 12 months to study effects on microRNA in brain tissue. The study found that rno-miR107 was decreased in exposed rats, while rno-miR-9-5p, rno-miR-29a-3p, rno-miR-106b-5p, and rno-miR-125a-3p were not altered.

Why This Matters

The study used 14 Wistar Albino adult male rats divided into an exposure group and a sham group of 7 rats each, with the sham group treated identically except the generator was turned off. The whole body radiofrequency exposure level was measured at a SAR value of 0.0369 W/kg. The researchers stated that 900 MHz radiofrequency radiation can alter some microRNA, which in turn may lead to adverse effects, and called for further studies.

Exposure Details

SAR
0.0369 W/kg
Source/Device
900 MHz
Exposure Duration
3 h per day (7 days a week) for 12 months (one year).

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 0.0369 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects observed in the Severe Concern range (Building Biology)FCC limit is 43 times higher than this level
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

The purpose of this study was to bridge this gap by investigating effects of long-term 900 MHz mobile phone exposure on some of the miRNA in brain tissue.

The study was carried out on 14 Wistar Albino adult male rats by dividing them into two groups: Sham...

Results revealed that long-term exposure of 900 MHz RF radiation only decreased rno-miR107 (adjP* = ...

900 MHz RF radiation can alter some of the miRNA, which, in turn, may lead to adverse effects. Therefore, further studies should be performed.

Cite This Study
Dasdag S, Akdag MZ, Erdal ME, Erdal N, Ay OI, Ay ME, Yilmaz SG, Tasdelen B, Yegin K. (2014). Long term and excessive use of 900 MHz radiofrequency radiation alter microrna expression in brain. Int J Radiat Biol. 2014 Dec 20:1-22.
Show BibTeX
@article{s_2014_long_term_and_excessive_925,
  author = {Dasdag S and Akdag MZ and Erdal ME and Erdal N and Ay OI and Ay ME and Yilmaz SG and Tasdelen B and Yegin K.},
  title = {Long term and excessive use of 900 MHz radiofrequency radiation alter microrna expression in brain.},
  year = {2014},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/25529971/},
}

Cited By (43 papers)

Quick Questions About This Study

The study used 14 Wistar Albino adult male rats split into two groups of 7.
Rats were exposed to 900 MHz radiofrequency radiation for 3 hours per day, 7 days a week, for 12 months.
Only rno-miR107 was decreased in the exposure group, with an adjusted p-value of 0.045.
The other microRNAs evaluated in the study were not altered by 900 MHz radiofrequency radiation.
The researchers stated that 900 MHz radiofrequency radiation can alter some microRNA, which in turn may lead to adverse effects, and called for further studies.