Exposure to 1950-MHz TD-SCDMA Electromagnetic Fields Affects the Apoptosis of Astrocytes via Caspase-3-Dependent Pathway.
Liu YX, Tai JL, Li GQ, Zhang ZW, Xue JH, Liu HS, Zhu H, Cheng JD, Liu YL, Li AM, Zhang Y. · 2012
View Original AbstractCell phone radiation at realistic exposure levels can kill healthy brain support cells by damaging their cellular powerhouses.
Plain English Summary
Researchers exposed rat brain support cells to cell phone radiation at 1950 MHz for 48 hours. The radiation damaged cellular powerhouses and triggered cell death through a specific pathway, though it didn't promote tumors. This suggests prolonged exposure may harm healthy brain cells.
Why This Matters
This study provides concerning evidence that cell phone radiation can damage healthy brain cells through well-understood biological mechanisms. The researchers used 1950 MHz TD-SCDMA radiation at 5.36 W/kg SAR, which is just above current safety limits of 2 W/kg but well within the range of exposures from phones held close to the head during calls. What makes this research particularly significant is that it identified the specific pathway through which EMF exposure kills astrocytes - brain cells that support and protect neurons. The mitochondrial damage and caspase-3 activation represent fundamental cellular stress responses that could have broader implications for brain health. While the study didn't find tumor-promoting effects, the death of healthy brain support cells raises different but equally important questions about long-term neurological impacts from chronic EMF exposure.
Exposure Details
- SAR
- 5.36 W/kg
- Source/Device
- 1950-MHz TD-SCDMA
- Exposure Duration
- 12, 24 and 48 h
Exposure Context
This study used 5.36 W/kg for SAR (device absorption):
- 13.4x above the Building Biology guideline of 0.4 W/kg
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
This study investigated whether EMF radiation would alter the biology of glial cells and act as a tumor-promoting agent.
We exposed rat astrocytes and C6 glioma cells to 1950-MHz TD-SCDMA for 12, 24 and 48 h respectively,...
A 48 h of exposure damaged the mitochondria and induced significant apoptosis of astrocytes. Moreove...
Show BibTeX
@article{yx_2012_exposure_to_1950mhz_tdscdma_127,
author = {Liu YX and Tai JL and Li GQ and Zhang ZW and Xue JH and Liu HS and Zhu H and Cheng JD and Liu YL and Li AM and Zhang Y. },
title = {Exposure to 1950-MHz TD-SCDMA Electromagnetic Fields Affects the Apoptosis of Astrocytes via Caspase-3-Dependent Pathway.},
year = {2012},
url = {https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042332},
}