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Extremely low-frequency electromagnetic fields affect the immune response of monocyte-derived macrophages to pathogens.

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Akan Z, Aksu B, Tulunay A, Bilsel S, Inhan-Garip A · 2010

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50 Hz magnetic fields at very high laboratory levels enhanced immune cells' bacteria-fighting ability, suggesting EMF immune effects are more complex than previously thought.

Plain English Summary

Summary written for general audiences

Researchers exposed immune cells to 50 Hz magnetic fields (power line frequency) while they fought bacterial infections. The magnetic field exposure boosted the cells' bacteria-fighting ability by increasing nitric oxide production and protective proteins. This suggests some EMF exposures might enhance rather than harm immune function.

Why This Matters

This study presents an intriguing counterpoint to concerns about EMF suppressing immune function. The researchers found that 50 Hz magnetic fields at 1 milliTesla enhanced macrophages' bacterial-fighting capabilities. To put this in perspective, 1 mT is roughly 20,000 times stronger than typical household magnetic field exposures, which range from 0.01 to 0.2 microtesla near common appliances. The science demonstrates that EMF effects on immunity aren't simply good or bad, but depend heavily on exposure parameters like frequency, intensity, and duration. What this means for you is that the immune system's response to EMF appears more complex than early research suggested. While this particular study used laboratory conditions with very high field strengths, it adds important nuance to our understanding of how electromagnetic fields interact with biological systems. The reality is that we need more research examining real-world exposure levels to determine whether everyday EMF encounters help or hinder immune function.

Exposure Details

Magnetic Field
1 mG
Source/Device
50 Hz
Exposure Duration
4–6 h

Exposure Context

This study used 1 mG for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 1 mGExtreme Concern5 mGFCC Limit2,000 mGEffects observed in the Severe Concern range (Building Biology)FCC limit is 2,000x higher than this exposure level

Study Details

This study aimed to determine the effect of extremely low‐frequency electromagnetic fields (ELF‐EMF) on the physiological response of phagocytes to an infectious agent.

THP‐1 cells (human monocytic leukemia cell line) were cultured and 50 Hz, 1 mT EMF was applied for 4...

The growth curve of exposed bacteria was lower than the control. Field application increased NO leve...

These data confirm that ELF‐EMF affects bacterial growth and the response of the immune system to bacterial challenges, suggesting that ELF‐EMF could be exploited for beneficial uses

Cite This Study
Akan Z, Aksu B, Tulunay A, Bilsel S, Inhan-Garip A (2010). Extremely low-frequency electromagnetic fields affect the immune response of monocyte-derived macrophages to pathogens. Bioelectromagnetics. 31(8):603-612, 2010.
Show BibTeX
@article{z_2010_extremely_lowfrequency_electromagnetic_fields_313,
  author = {Akan Z and Aksu B and Tulunay A and Bilsel S and Inhan-Garip A},
  title = {Extremely low-frequency electromagnetic fields affect the immune response of monocyte-derived macrophages to pathogens.},
  year = {2010},
  doi = {10.1002/bem.20607},
  url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/bem.20607},
}

Quick Questions About This Study

Researchers exposed immune cells to 50 Hz magnetic fields (power line frequency) while they fought bacterial infections. The magnetic field exposure boosted the cells' bacteria-fighting ability by increasing nitric oxide production and protective proteins. This suggests some EMF exposures might enhance rather than harm immune function.