Gao X, Luo R, Ma B, Wang H, Liu T, Zhang J, Lian Z, Cui X · 2013
Radiation exposure decreased SOD and GSH-Px activity and increased MDA levels in both pregnant and fetal rats, and caused mitochondrial swelling, edema, and chromatin condensation in fetal brain tissue. Vitamin E supplementation reversed these changes in a dose-dependent manner, with all three doses increasing SOD and GSH-Px in fetal rats, and middle and high doses decreasing MDA in fetal rats and high dose doing so in pregnant rats.
Tsybulin O et al. · 2013
Japanese quail embryos were exposed in ovo to GSM 900 MHz radiation for 38 hours or 158 hours with a 48-second on, 12-second off cycle at an average power density of 0.25 μW/cm(2) and a specific absorption rate of 3 μW/kg. The number of differentiated somites was assessed microscopically and DNA damage was assessed by an alkaline comet assay. After 38 hours the number of differentiated somites increased and DNA strand breaks decreased, while after 158 hours the number of differentiated somites decreased and DNA damage increased.
Luo Q, Jiang Y, Jin M, Xu J, Huang HF. · 2013
Researchers exposed pregnant volunteers at about 50 days gestation to cell phone EMF at 1.6 to 8.8 W/kg for one hour. They used two-dimensional electrophoresis to examine protein profile changes and found up to 15 spots with significant 2- to 2.5-fold changes compared to sham-exposed group. Twelve proteins were identified, including procollagen-proline, eukaryotic translation elongation factor 1 delta, and others.
Atasoy HI, Gunal MY, Atasoy P, Elgun S, Bugdayci G · 2013
Researchers exposed male rats to radiofrequency radiation from Wi-Fi devices operating at 2.437 GHz for 24 hours a day for 20 weeks, then examined their testes. The exposed rats showed significant increases in markers indicating DNA damage in the testes compared to controls. Catalase and glutathione peroxidase activity were decreased in the exposed group, which the researchers suggested may have been due to radiofrequency effects on enzyme activity. The researchers said these findings raise questions about the safety of radiofrequency exposure from Wi-Fi Internet access devices for growing organisms of reproductive age, with a potential effect on both fertility and the integrity of germ cells.
Haghani M, Shabani M, Moazzami K · 2013
Researchers exposed pregnant Wistar rats to 900-MHz pulse-EMF irradiation for 6 hours per day throughout gestation, then evaluated ten offspring per group. Behavioral tests did not reveal any abnormalities in the exposed offspring. Whole-cell patch clamp recordings revealed decreased neuronal excitability of Purkinje cells, with changes in afterhyperpolarization amplitude, spike frequency, half width, and first spike latency.
Mild KH, Andersen JB, Pedersen GF. · 2012
Several earlier studies used a GSM phone in stand-by mode as an exposure source and reported effects on sleep and testicular function. The authors explain that in stand-by mode the phone is only active during periodic location updates set by the network operator. Typical updates occur every 2 to 5 hours, and between updates the phone acts as a passive receiver with no microwave emission. They conclude that exposure in stand-by mode can be considered negligible.
Panagopoulos DJ · 2012
Researchers studied the effect of GSM radiation on ovarian development in virgin Drosophila melanogaster females. Exposed insects had significantly smaller ovaries due to destruction of egg chambers from DNA damage and cell death. The ovarian size difference peaked at 39-45 hours after eclosion and then decreased as mature eggs were laid in sham-exposed flies.
Ozlem Nisbet H, Nisbet C, Akar A, Cevik M, Karayigit MO · 2012
Mouradi R, Desai N, Erdemir A, Agarwal A · 2012
The aim was to calculate the distance between a cell phone and a semen sample to set up an in vitro experiment that mimics real-life conditions with a phone in a trouser pocket separated by multiple tissue layers. The results indicated that the distance should be 0.8 cm to 1.8 cm greater than the anticipated distance between a cell phone and the testes. A computational model of scrotal tissues was designed considering the separating layers and used in simulations with the Finite Difference Time Domain method.
Ingole IV, Ghosh SK. · 2012
Researchers exposed chick embryos to radiofrequency radiation emitted by a cell phone by varying the duration of exposure to create different doses. Light microscopic examination revealed that developing dorsal root ganglion neurons suffered damage that was dose dependent. The damage persisted even when exposure-free periods were given between exposures.
Hässig M, Jud F, Spiess B. · 2012
Researchers examined a dairy farm where many calves were born with nuclear cataracts after a mobile phone base station was erected near the barn. Calves born there had a 3.5 times higher risk of heavy cataract compared to the Swiss average. The investigators excluded usual causes such as infection or poisoning, but the real cause of the increased incidence remains unknown.
Eskander EF, Estefan SF, Abd-Rabou AA. · 2012
Researchers assessed the role of exposure to radio frequency radiation from mobiles or base stations on human hormone profiles. The study showed significant decreases in volunteers' ACTH, cortisol, thyroid hormones, prolactin for young females, and testosterone levels.
Celik S, Aridogan IA, Izol V, Erdoğan S, Polat S, Doran S. · 2012
Researchers placed Wistar-Kyoto male rats into a control group with inactive cell phones and an experimental group with active cell phones for three months. No significant differences were found in testis weight, seminiferous tubule diameter, or histopathological evaluation between the groups. Electron microscopy showed increased membrana propria thickness, increased collagen fibers, extended capillary veins, vacuolization in Sertoli cells, electron-dense structures, and large lipid droplets in the exposed rats.
Baste V, Moen BE, Oftedal G, Strand LA, Bjørge L, Mild KH. · 2012
The study was a cohort study of Royal Norwegian Navy servicemen linked to the Medical Birth Registry of Norway, including singleton offspring born between 1967 and 2008 (n = 37,920). Exposure during the last 3 months before conception (acute) and exposure more than 3 months before conception (nonacute) were analyzed. Perinatal mortality and preeclampsia increased after service aboard fast patrol boats during an acute period and also after increased estimated radiofrequency exposure during an acute period, compared with service aboard other vessels. No associations were found between nonacute exposure and any of the reproductive outcomes.
Avendaño C, Mata A, Sanchez Sarmiento CA, Doncel GF. · 2012
Researchers exposed sperm from 29 healthy donors to a Wi-Fi-connected laptop for four hours. Exposed sperm had significantly lower progressive motility and more DNA fragmentation than unexposed sperm. Sperm viability did not differ between groups.
Al-Damegh MA. · 2012
The study exposed rats to an electromagnetic field for 15, 30, and 60 minutes daily over two weeks, with some groups receiving vitamin C (40 mg/kg/day) or vitamin E (2.7 mg/kg/day). Electromagnetic exposure significantly increased seminiferous tubule diameter and caused disorganized sperm cycle interruption. It also raised serum and testicular conjugated diene, lipid hydroperoxide, and catalase activities threefold while decreasing glutathione and glutathione peroxidase levels three to fivefold. The authors concluded that the electromagnetic frequency negatively affected testicular architecture and enzymatic activity and that vitamins C and E may mitigate oxidative stress and restore normality.
Kesari KK, Behari J. · 2012
Seventy-day-old Wistar rats were exposed to mobile phone radiofrequency radiation for two hours per day for 45 days and compared with a sham-exposed group. RF-exposed animals had a significant decrease in testosterone and an increase in caspase-3 activity. Distortions in sperm head and mid piece of sperm mitochondrial sheath were observed via transmission electron microscopy. Progeny from RF-exposed rats showed significant decreases in number and weight compared to sham-exposed animals.
Jing J, Yuhua Z, Xiao-qian Y, Rongping J, Dong-mei G, Xi C. · 2012
Thirty-two pregnant rats were divided into four groups, with three groups receiving microwave radiation for 10, 30, or 60 minutes three times daily from the first day of pregnancy for 20 days. In the 30-minute and 60-minute exposure groups, superoxide dismutase and glutathione peroxidase decreased while malondialdehyde increased compared with controls. Noradrenaline and dopamine levels increased in the 10-minute exposure group but decreased in the 60-minute exposure group. The authors concluded that prenatal microwave radiation from cellular phones has certain harm on fetal rat brains.
Tsybulin O, Sidorik E, Kyrylenko S, Henshel D, Yakymenko I. · 2012
Researchers exposed fresh fertilized Japanese quail eggs to GSM 900 MHz cell phone radiation at 0.2 μW/cm² for either 38 hours or 14 days. The 38-hour exposure significantly increased the number of differentiated somites, and the 14-day exposure significantly increased total embryo survival. Hatchlings from exposed eggs showed significantly higher levels of thiobarbituric acid reactive substances in brain and liver tissue.
Kumar S, Behari J, Sisodia R. · 2012
Researchers exposed 70-day-old male Wistar rats to 10 GHz microwave radiation for 2 h per day for 45 days at power density 0.21 mW/cm(2) and SAR of 0.014 W/kg, with a sham-exposed control group. Scanning electron microscopy revealed shrinkage of the seminiferous tubule lumen, and apoptotic bodies were present in the exposed group. Flow cytometry showed micronuclei formation in lymphocytes, comet assay confirmed DNA strand breaks, and testosterone levels were significantly decreased alongside testicular shrinkage.
Kumar S, Behari J, Sisodia R. · 2012
Researchers exposed 70-day-old male albino rats to 10-GHz EMF for 2 hours a day over 45 days. Creatine kinase phosphorylation increased in sperm after exposure. Melatonin and MDA levels decreased in exposed rats. The authors concluded that microwave exposure could adversely affect male fertility.
Redmayne M, Smith E, Abramson MJ. · 2011
Researchers explored school cellphone rules and adolescent exposure to cellphone microwave emissions during school using a census and survey. All schools banned private use of cellphones in class, but 43% of student participants admitted breaking this rule. A high-exposure group of risk-takers was identified for whom prohibited in-school use was positively associated with high texting rates, carrying the phone switched-on >10h/day, and in-pocket use. The authors reviewed reproductive bio-effect papers and concluded there is sufficient evidence and expert opinion to warrant an enforced school policy removing cellphones from students during the day.
Lee HJ et al. · 2011
Researchers examined the effects of combined exposure to radiofrequency electromagnetic fields on rat testicular function, specifically spermatogenesis. Male rats were exposed to CDMA and WCDMA RF signals for 12 weeks at 45 minutes per day, 5 days per week, with a whole-body average SAR of 2.0 W/kg each or 4.0 W/kg total. They investigated sperm count, testosterone concentration, malondialdehyde concentrations, spermatogenesis stages, and apoptotic cells in the testes.
Imai N, Kawabe M, Hikage T, Nojima T, Takahashi S, Shirai T. · 2011
Researchers exposed male Sprague-Dawley rats to a 1.95 GHz W-CDMA signal for 5 hours per day, 7 days a week for 5 weeks at whole-body SARs of 0.4 and 0.08 W/kg. There were no differences in body weight gain or weights of the testis, epididymis, seminal vesicles, and prostate among the groups. The number of sperm in the testis and epididymis were not decreased in the EMF exposed groups, and the testicular sperm count was significantly increased with the 0.4 SAR. Abnormalities of sperm motility or morphology and the histological appearance of seminiferous tubules, including the stage of the spermatogenic cycle, were not observed. Thus, under the present exposure conditions, no testicular toxicity was evident.
Divan HA, Kheifets L, Olsen J · 2011
Researchers used data from the Danish National Birth Cohort to examine prenatal cell phone use and developmental milestone delays in offspring up to 18 months of age. At 6 months the adjusted odds ratio for cognitive/language delay was 0.8 (95% CI 0.7-1.0) and for motor delay was 0.9 (95% CI 0.8-1.1). At 18 months the adjusted odds ratio for cognitive/language delay was 1.1 (95% CI 0.9-1.3) and for motor delay was 0.9 (95% CI 0.8-1.0). The researchers observed no evidence of an association and dose-response associations were also null.
