Unknown authors · 2009
A research team from ISS searched for a suitable location to implement an epidemiological study aimed at a wide range of outcomes for which a priori hypotheses could be formulated. The project's recently published findings showed an increase in primary and secondary malignant neoplasms, ischaemic disease, and haematological diseases. The authors recommended that future studies address the most exposed sectors of the population, consider different outcomes, and follow protocols that enable pooled analyses.
Piacentini R, Ripoli C, Mezzogori D, Azzena GB, Grassi C. · 2008
Unknown authors · 2008
Researchers exposed the human keratinocyte cell line HaCaT to 1 mT, 50 Hz ELF-EMF for different lengths of time and compared them with unexposed control cells. Cell growth and viability were evaluated by cell count and trypan blue exclusion. Significantly increased growth rates were observed after 48 hours of EMF exposure compared with control cells, while no difference in cell viabilities was detected. Gene expression and release of RANTES, MCP-1, MIP-1 alpha and IL-8 were significantly reduced after 72 hours of exposure. NF-kappaB levels became almost undetectable after only 1 hour of EMF exposure and were inversely correlated with cell density.
Unknown authors · 2008
Unknown authors · 2008
Researchers exposed Escherichia coli ATCC 700926 to 50 Hz electromagnetic fields at 0.1, 0.5, and 1.0 mT and compared them with sham-exposed controls. Exposed and control samples had similar total and culturable counts. Exposed samples showed increased cell viability after 24 hours of re-incubation outside the solenoid. Exposure for 20–120 minutes caused significant morphological changes including coccoid cells and atypical lengthened forms. DNA fingerprinting showed no changes, while RNA-AFLP analysis revealed some differences at each field intensity.
Unknown authors · 2008
Researchers exposed E. coli bacteria to 50 Hz electromagnetic fields (the same frequency as power lines) at various intensities for up to 2 hours. While the bacteria survived normally, they showed signs of stress including changed cell shapes, clustering behavior, and altered gene activity. This suggests that power line frequency EMF acts as a biological stressor even in simple organisms.
Croft RJ et al. · 2008
Researchers exposed 120 healthy volunteers to mobile phone electromagnetic fields for 30 minutes while monitoring their brain waves using EEG technology. They found that mobile phone radiation increased alpha brain wave activity (the relaxed, wakeful state waves) during exposure, with stronger effects on the side of the head closest to the phone. This confirms that mobile phone EMF can directly alter normal brain function in measurable ways.
Falone S et al. · 2008
Scientists exposed young and old rats to power-line magnetic fields for 10 days. Young rats strengthened their brain's protective systems, but older rats experienced weakened defenses against cellular damage. This suggests aging makes brains more vulnerable to magnetic field exposure from electrical devices.
Koh EK, Ryu BK, Jeong DY, Bang IS, Nam MH, Chae KS · 2008
Researchers examined the effects of power frequency magnetic fields on cell growth in DU145, PC3, and LNCaP prostate cancer cells in vitro. The cells were exposed to various intensities and durations of 60-Hz sinusoidal magnetic fields with various serum concentrations. MF exposure induced significant cell growth inhibition and apoptosis in an intensity- and time-dependent manner, with increased cell cycle arrest, cleaved Caspase-3, and reactive oxygen species. Pretreatment with a Caspase-3 inhibitor or the antioxidant N-acetyl-L-cysteine significantly attenuated the magnetic field-induced growth inhibition and cell death. Media replacement experiments did not alter the magnetic field effects.
Unknown authors · 2008
Exposure did not significantly affect body weight or testosterone levels. TUNEL staining revealed a significantly higher apoptotic rate in germ cells of exposed mice compared to sham controls, with TUNEL-positive cells mainly being spermatogonia. Electron microscopy showed degenerating spermatogonia with condensation of nuclear chromatin similar to apoptosis.
Unknown authors · 2008
Researchers exposed mice to 60 Hz magnetic fields at 14 microT (similar to levels near power lines) for 16 weeks and found significantly increased death of sperm-producing cells in the testes. The magnetic field exposure didn't affect body weight or testosterone levels, but caused programmed cell death specifically in spermatogonia, the cells that develop into sperm. This suggests that everyday magnetic field exposures could potentially impact male fertility.
Yokus B, Akdag MZ, Dasdag S, Cakir DU, Kizil M · 2008
Levels of FapyAde, FapyGua, and 8OHdG were increased at both intensities compared to cage-control and sham groups, but statistical significance was observed only in the group exposed to 100 μT. The researchers noted that the intensity of ELF-MF has an important influence on the extent of DNA damage.
Fu Y, Wang C, Wang J, Lei Y, Ma Y · 2008
Researchers exposed mice to 25 or 50 Hz electromagnetic fields for either 7 days or 25 days and then tested them in the Y-maze. Long-term exposure to 50 Hz fields reduced recognition of the novel arm. Neither short- nor long-term exposure to magnetic fields affected the locomotor activity of mice in the Y-maze.
Fu Y, Wang C, Wang J, Lei Y, Ma Y. · 2008
Chinese researchers exposed mice to extremely low-frequency magnetic fields (the same type emitted by power lines and household appliances) for either 7 or 25 days, then tested their spatial memory using a maze. While short-term exposure had no effect, mice exposed to 50 Hz fields for 25 days showed impaired ability to recognize new areas in the maze. This suggests that chronic exposure to power-frequency magnetic fields may interfere with spatial memory and navigation abilities.
George I et al. · 2008
Researchers exposed Sprague-Dawley rats to a 60 Hz, 8 µT electromagnetic field for 30 minutes before inducing ischemia-reperfusion (I-R) injury to the heart. Significant upregulation of the HSP70 gene and increased hsp70 levels were measured in response to EMF pre-exposures. Systolic contractile function showed significant recovery after 30 minutes of reperfusion in EMF-exposed animals, and diastolic function was markedly improved as well.
Unknown authors · 2008
Researchers exposed mouse osteoblast-like MC3T3-E1 cells to ELF-EMF at 3 mT and 60 Hz and measured cellular collagen as a marker of differentiation. ELF-EMF exposure significantly increased collagen content in the cells. Inhibiting the p38 MAPK pathway with SB203580 suppressed the ELF-EMF-induced collagen increase, while inhibiting the PI3K pathway with LY294002 accelerated it. The ERK1/2 inhibitor PD98059 reduced collagen in all conditions but did not block the ELF-EMF effect.
Unknown authors · 2008
Researchers measured 50 Hz magnetic fields in 31 apartment buildings with built-in transformer stations. In each building they selected three apartments: one above the transformer room, one on the same floor, and one on a higher floor. The mean magnetic field was 0.98 microT above transformers, 0.13 microT on the same floor, and 0.1 microT on higher floors. At a 0.2 microT threshold, 97% of apartments above transformers exceeded it versus 14% on the same floor and 13% on higher floors. At 0.4 microT, 81% of apartments above transformers exceeded it while none on other floors did.
Unknown authors · 2008
Researchers investigated the effects of 50 Hz magnetic fields on DNA damage response in murine L929 cells. Cells were exposed to magnetic fields at 100 or 300 microT combined with menadione or UVB radiation using various exposure schedules. Pre-exposure to 100 microT magnetic fields for 24 hours before menadione treatment decreased the proportion of sub G1 cells and increased the proportion of cells in G2/M phase. Exposure to 300 microT magnetic fields also decreased the proportion of cells in G1 phase. Magnetic field exposure after menadione treatment did not alter the response, and no effects were seen from magnetic fields alone or combined with UVB radiation.
Unknown authors · 2008
Guler G, Turkozer Z, Tomruk A, Seyhan N · 2008
Koyama S, Sakurai T, Nakahara T, Miyakoshi J · 2008
Researchers measured apurinic/apyrimidinic (AP) sites in human glioma A172 cells after exposure to extremely low frequency (ELF) magnetic fields, genotoxic chemicals, or both. ELF magnetic fields alone produced no difference in AP sites compared with sham controls. The results suggest that the number of AP sites induced by MMS or H2O2 is enhanced by exposure to ELF magnetic fields at 5 millitesla (mT).
Unknown authors · 2008
Researchers used the SOD-1 mouse model to assess the possible effect of ELF magnetic fields on ALS development. Seven mice per group were exposed to 50 Hz magnetic fields at 100 and 1000 microT(rms) before clinical signs of ALS appeared. Exposure lasted 7 weeks while body weight, motor performance, and life span were monitored. The results showed no evidence of a link between ELF exposure and ALS in this transgenic animal model.
Unknown authors · 2008
Researchers studied 46 spot welders exposed to extremely low frequency magnetic fields (50 Hz, 8.8-84 microTesla) and found their red blood cells had significantly reduced antioxidant enzyme activity compared to unexposed workers. The study showed a 22% decrease in superoxide dismutase and 12.3% decrease in glutathione peroxidase, suggesting these magnetic fields act as oxidative stressors even at recommended exposure levels.
Unknown authors · 2008
Researchers studied 46 spot welders exposed to extremely low frequency magnetic fields (50 Hz, 8.8-84 microTesla) and found their red blood cells had significantly reduced antioxidant enzyme activity compared to unexposed workers. The stronger the magnetic field exposure, the greater the reduction in protective enzymes that normally defend cells against oxidative damage.
Unknown authors · 2008
Researchers used a rat model of chemically induced B acute lymphoblastic leukemia to test effects of 50 Hz magnetic fields with and without harmonics. The experiment included 280 rats and compared body weight, survival time, bone marrow blast cells, cumulative leukemia incidence, and leukemia type between exposed and unexposed groups. No significant differences were found for any parameter (p > 0.05). Results did not support the hypothesis that ELF-MFs, with or without harmonics, affect the development of B acute lymphoblastic leukemia in children.
