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2-GHz band CW and W-CDMA modulated radiofrequency fields have no significant effect on cell proliferation and gene expression profile in human cells.

No Effects Found

Sekijima M, Takeda H, Yasunaga K, Sakuma N, Hirose H, Nojima T, Miyakoshi J. · 2010

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This study found no cellular damage from 3G-level RF exposure within safety limits, but represents just one piece of mixed research.

Plain English Summary

Summary written for general audiences

Japanese researchers exposed human brain cells and lung cells to 2.1 GHz radiofrequency radiation (similar to 3G cell phones) for up to 96 hours at various power levels. They found no significant changes in cell growth, survival, or gene expression patterns compared to unexposed cells. The study suggests that RF exposure within current safety guidelines doesn't trigger obvious cellular stress responses in laboratory conditions.

Study Details

We investigated the mechanisms by which radiofrequency (RF) fields exert their activity, and the changes in both cell proliferation and the gene expression profile in the human cell lines, A172 (glioblastoma), H4 (neuroglioma), and IMR-90 (fibroblasts from normal fetal lung) following exposure to 2.1425 GHz continuous wave (CW) and Wideband Code Division Multiple Access (W-CDMA) RF fields at three field levels.

During the incubation phase, cells were exposed at the specific absorption rates (SARs) of 80, 250, ...

No significant differences in cell growth or viability were observed between any test group exposed ...

These results suggest that RF exposure up to the limit of whole-body average SAR levels as specified in the ICNIRP guidelines is unlikely to elicit a general stress response in the tested cell lines under these conditions.

Cite This Study
Sekijima M, Takeda H, Yasunaga K, Sakuma N, Hirose H, Nojima T, Miyakoshi J. (2010). 2-GHz band CW and W-CDMA modulated radiofrequency fields have no significant effect on cell proliferation and gene expression profile in human cells. J Radiat Res. 51(3):277-284, 2010.
Show BibTeX
@article{m_2010_2ghz_band_cw_and_3389,
  author = {Sekijima M and Takeda H and Yasunaga K and Sakuma N and Hirose H and Nojima T and Miyakoshi J.},
  title = {2-GHz band CW and W-CDMA modulated radiofrequency fields have no significant effect on cell proliferation and gene expression profile in human cells.},
  year = {2010},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/20215713/},
}

Quick Questions About This Study

Japanese researchers exposed human brain cells and lung cells to 2.1 GHz radiofrequency radiation (similar to 3G cell phones) for up to 96 hours at various power levels. They found no significant changes in cell growth, survival, or gene expression patterns compared to unexposed cells. The study suggests that RF exposure within current safety guidelines doesn't trigger obvious cellular stress responses in laboratory conditions.