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Disturbance of cell proliferation in response to mobile phone frequency radiation.

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Trosić I, Pavicić I. · 2009

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Cell proliferation declined 72 hours after three hours of exposure, microtubule structure was altered immediately, and mitotic index did not differ from controls.

Plain English Summary

Summary written for general audiences

The study aimed to determine the influence of mobile phone frequency radiation on proliferation, cytoskeleton structure, and mitotic index of V79 cells after 1, 2, and 3 hours of exposure. V79 cells were exposed to continuous-wave 935 MHz radiation at an electric field strength of (8.2+/-0.3) V m(-1) and a specific absorption rate of 0.12 W kg(-1). Cell proliferation declined in cells exposed for three hours when measured 72 hours after irradiation. Microtubule structure was clearly altered immediately after three hours of irradiation. The mitotic index in exposed cells did not differ from negative controls.

Why This Matters

The authors suggested that microtubule impairment may have slowed cell division kinetics despite no change in the number of dividing cells. Proliferation kinetics were assessed by counting cells at 24, 48, 72, and 96 hours after each exposure duration. Microtubule proteins were detected using immunocytochemical methods and cell smears were analysed under a fluorescent microscope.

Exposure Details

SAR
0.12 W/kg
Electric Field
8.2+/-0.3 V/m
Source/Device
935 MHz
Exposure Duration
1 h, 2 h, and 3 hours

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 0.12 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 13 times higher than this level
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 935 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 935 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

The aim of study was to determine the influence of mobile phone frequency radiation on the proliferation, cytoskeleton structure, and mitotic index of V79 cells after 1 h, 2 h, and 3 h of exposure.

V79 cells were cultured in standard laboratory conditions and exposed to continuous-wave (CW) RF/MW ...

In comparison to the controls, cell proliferation declined in cells exposed for three hours 72 h aft...

Cite This Study
Trosić I, Pavicić I. (2009). Disturbance of cell proliferation in response to mobile phone frequency radiation. Arh Hig Rada Toksikol. 60(1):109-115, 2009.
Show BibTeX
@article{i_2009_disturbance_of_cell_proliferation_1383,
  author = {Trosić I and Pavicić I.},
  title = {Disturbance of cell proliferation in response to mobile phone frequency radiation.},
  year = {2009},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/19329382/},
}
PubMed: 19329382

Cited By (20 papers)

Quick Questions About This Study

The study aimed to determine the influence of mobile phone frequency radiation on proliferation, cytoskeleton structure, and mitotic index of V79 cells after 1, 2, and 3 hours of exposure.
V79 cells were exposed to continuous-wave 935 MHz radiation at an electric field strength of (8.2+/-0.3) V m(-1) and a specific absorption rate of 0.12 W kg(-1).
Cell proliferation declined in cells exposed for three hours when measured 72 hours after irradiation.
Microtubule structure was clearly altered immediately after three hours of irradiation.
The mitotic index in exposed cells did not differ from negative controls.