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Does static magnetic field-exposure induced oxidative stress and apoptosis in rat kidney and muscle? Effect of vitamin E and selenium supplementations.

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Ghodbane S, Lahbib A, Ammari M, Sakly M, Abdelmelek H. · 2015

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Static magnetic field exposure caused 25% more oxidative stress in rat kidneys, but selenium and vitamin E prevented this damage.

Plain English Summary

Summary written for general audiences

Researchers exposed rats to strong magnetic fields for one hour daily over five days. The exposure increased oxidative stress markers by 25-34% in kidney tissue but not muscle. Selenium and vitamin E supplements prevented this kidney damage, suggesting antioxidants may protect against magnetic field effects.

Why This Matters

This study adds to the growing body of evidence showing that magnetic field exposure can trigger oxidative stress, the cellular damage process linked to aging and disease. The 128 mT exposure level is significantly higher than typical household sources (which range from 0.1-1 mT near appliances), but it's within the range of some occupational exposures and certain medical devices. What makes this research particularly valuable is that it demonstrates tissue-specific effects - the kidneys showed damage while muscle tissue didn't, suggesting that some organs may be more vulnerable to magnetic field exposure than others. The protective effect of selenium and vitamin E supplementation offers a practical insight: antioxidants may help mitigate EMF-induced cellular stress, though this doesn't eliminate the need for exposure reduction.

Exposure Details

Magnetic Field
128 mG
Exposure Duration
1 h/day for 5 days

Exposure Context

This study used 128 mG for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 128 mGExtreme Concern5 mGFCC Limit2,000 mGEffects observed in the Extreme Concern range (Building Biology)FCC limit is 16x higher than this exposure level

Study Details

Our aim was to study whether SMF induces oxidative stress and apoptosis in rat tissues and to evaluate the possible protector effect of selenium (Se) and vitamin E (vit E) supplementations.

Rats were randomly divided into control, SMF-exposed, Se-treated, vit E-treated, SMF exposed rats an...

Exposure of rats to SMF (128 mT, 1 h/day for 5 days) increased the MDA concentrations (+25%) and CAT...

In conclusion, exposure to SMF induced oxidative stress in kidney that can be prevented by treatment with Se or vit E.

Cite This Study
Ghodbane S, Lahbib A, Ammari M, Sakly M, Abdelmelek H. (2015). Does static magnetic field-exposure induced oxidative stress and apoptosis in rat kidney and muscle? Effect of vitamin E and selenium supplementations. Gen Physiol Biophys. 34(1):23-32, 2015b.
Show BibTeX
@article{s_2015_does_static_magnetic_fieldexposure_374,
  author = {Ghodbane S and Lahbib A and Ammari M and Sakly M and Abdelmelek H.},
  title = {Does static magnetic field-exposure induced oxidative stress and apoptosis in rat kidney and muscle? Effect of vitamin E and selenium supplementations.},
  year = {2015},
  
  url = {https://europepmc.org/article/med/25395602},
}

Quick Questions About This Study

Researchers exposed rats to strong magnetic fields for one hour daily over five days. The exposure increased oxidative stress markers by 25-34% in kidney tissue but not muscle. Selenium and vitamin E supplements prevented this kidney damage, suggesting antioxidants may protect against magnetic field effects.