Lagroye I et al. · 2004
The study aimed to investigate the effect of 2450 MHz pulsed-wave microwaves on DNA damage in rat brain cells and whether proteinase K is needed to detect such damage. Rats exposed to γ-rays showed significant DNA damage using both comet assay versions independent of proteinase K. Neither assay version detected any difference in comet length or normalized comet moment between sham-exposed and microwave-exposed rats regardless of proteinase K inclusion. No DNA damage was detected in brain cells after exposure to 2450 MHz pulsed-wave microwaves at 1.2 W kg−1 regardless of proteinase K inclusion. The results support the conclusion that low-level 2450 MHz pulsed-wave microwave exposures do not induce DNA damage detectable by the alkaline comet assay.
Papageorgiou CC et al. · 2004
Ten women and nine men performed a short memory task during baseline and during exposure to a 900 MHz signal. Baseline EEG energy was higher in men than in women, and EMF exposure decreased EEG energy in men but increased it in women. Memory performance did not change with EMF exposure or gender.
Martinez-Burdalo M, Martin A, Anguiano M, Villar R · 2004
Peak SAR1g and SAR10g trended downwards as head size decreased. The percentage of energy absorbed in the brain increased with smaller head size. SAR distributions in eyes were very similar between full-size and scaled models.
Maier R, Greter SE, Maier N · 2004
Researchers tested cognitive processing in 11 volunteers using an auditory discrimination task under GSM-standard pulsed electromagnetic field exposure and field-free conditions. After a first test cycle, volunteers relaxed for 50 minutes with or without field exposure, then repeated the test, and data before and after the resting phase were compared. Nine of 11 participants (81.8%) showed worse auditory discrimination performance during field exposure compared to control, with group data reaching statistical significance (P = 0.0105).
Maby E et al. · 2004
Researchers studied GSM phone radiofrequency effects on human cerebral activity using auditory evoked potentials. N100 amplitudes were reduced under GSM radiofrequency influence with mean attenuation of -0.36 microV for healthy subjects and -0.60 microV for epileptic patients. Healthy subjects also showed a N100 latency decrease of -5.23 ms in mean. The auditory cortical activity was modified but an effect on brain functionality has not been proven.
Grant H, Heirman D, Kuriger G, Ravindran MM. · 2004
The study investigated electromagnetic interaction between current cell phone technology and specific models of Cyberonics neural stimulators. Out of 1080 test runs conducted, no interactions were observed. The phone technologies examined did not adversely affect the Cyberonics NeuroStar Model 102 NeuroCybernetic Prosthesis System.
Curcio G et al. · 2004
Researchers randomly assigned subjects to two groups exposed to 902.40 MHz EMF either before or during testing sessions. Subjects completed four performance tasks under double-blind conditions while tympanic temperature was measured five times per session. Results showed improved simple and choice reaction times and increased local temperature on the exposed region after at least 25 minutes of exposure.
Berg G, Schuz J, Samkange-Zeeb F, Blettner M. · 2004
Researchers validated self-reported mobile phone use by comparing it with cumulative emitted power measured by software-modified phones used by 45 volunteers for one month. Self-reported call number correlated with cumulative power at 0.50 and call duration at 0.48, each explaining about 23% of the variance in emitted power. Adding confounding factors such as network provider, contract form, and phone model increased explained variance to 26%, while using the phone while driving or in urban or rural areas showed no association with cumulative power.
Ilhan A et al. · 2004
Researchers investigated the effect of Ginkgo biloba on mobile phone-induced oxidative damage in rat brain tissue. Mobile phone exposure increased malondialdehyde, nitric oxide, xanthine oxidase, and adenosine deaminase while decreasing superoxide dismutase and glutathione peroxidase activities in brain tissue. Ginkgo biloba treatment prevented these oxidative alterations and the mobile phone-induced cellular injury in brain tissue.
Paulraj R, Behari J · 2004
Protein kinase C activity was measured in whole brain, hippocampus, and whole brain minus hippocampus after exposure. A significant decrease in enzyme level was observed in exposed rats compared to sham-exposed rats.
Mausset-Bonnefont AL et al. · 2004
Researchers used a head-only exposure device to expose rats to 900-MHz pulsed microwaves at 6 W/kg for 15 minutes. The exposure induced a strong glial reaction in the brain, particularly in the striatum. Significant immediate effects were observed on the Kd and Bmax values of NMDA and GABA(A) receptors and on dopamine transporters, along with a decrease in NMDA receptors at the postsynaptic membrane. General locomotor behavior was not significantly altered in the short term.
Lai H. · 2004
Microwave-exposed rats had a significant deficit in learning the platform location compared with sham-exposed rats. Noise exposure alone did not affect performance, but simultaneous noise exposure significantly reduced the microwave-induced learning deficit. In the probe trial, microwave-exposed rats spent less time in the target quadrant, whereas microwave-plus-noise rats performed like sham rats.
Hinrikus H, Parts M, Lass J, Tuulik V. · 2004
Twenty healthy volunteers were exposed to 450 MHz microwaves with 7 Hz on-off modulation, with a field power density of 0.16 mW/cm2 at the scalp. The study focused on the effect of low level microwave radiation on human EEG alpha and theta rhythms. Microwave and photic exposure did not cause statistically significant changes in EEG activity for the whole group, though changes varied strongly from subject to subject.
Cassel JC, Cosquer B, Galani R, Kuster N. · 2004
Rats were tested in a 12-arm radial-maze after daily exposure to 2.45 GHz microwaves for 45 minutes at a SAR of 0.6 W/kg. The performance of exposed rats was comparable to that found in sham-exposed or in naive rats.
Anderson LE et al. · 2004
Researchers set out to determine whether long-term exposure to a 1.6 GHz radiofrequency field would affect cancer incidence in Fischer 344 rats. Offspring were exposed to near-field radiofrequency signals at brain SAR levels of 1.6 W/kg or 0.16 W/kg for 2 hours per day, 5 days per week, from about 36 days old until they were 2 years old. No statistically significant differences were found among treatment groups for neoplastic lesions or other clinical signs.
Kramarenko AV, Tan U. · 2003
Researchers used a 16-channel telemetric electroencephalograph to record EEG changes during exposure of the human skull to EMF from a mobile phone. During exposure, median frequency increased in areas close to the antenna after 10-15 seconds, and slow-wave activity (2.5-6.0 Hz) appeared in contralateral frontal and temporal areas after 20-40 seconds. The slow waves lasted about one second and repeated every 15-20 seconds, and both the slow-wave activity and increased median frequency disappeared after the phone was turned off.
Kizilay A et al. · 2003
Researchers investigated the effects of chronic mobile phone EMF exposure on the inner ear of adult and developing rats using distortion product otoacoustic emissions (DPOAEs). In a sham-controlled design, seven of 14 adult rats and four newborn rats were exposed to mobile phone EMF for 1 hour per day over 30 days, while seven adult rats served as controls. DPOAEs were measured before and after exposure, and no measurable EMF-associated changes were found in either adult or developing rats (P>0.05).
Kainz W, Alesch F, Chan DD. · 2003
Researchers tested 10 GSM phones at 900 MHz and 10 at 1800 MHz on the ITREL-III deep brain stimulator in a phantom model. At maximum phone power of 2 W at 900 MHz and 1 W at 1800 MHz, no influence on the stimulator was observed, and pulse shape and single pulses remained unchanged. However, tests with continuous-wave signals showed inhibition occurs at power levels below GSM phone emissions, with the device more sensitive at 1800 MHz than at 900 MHz and a very low interference threshold around 1500 MHz. The authors concluded no direct risk for patients using the tested phones but recommended precautions similar to cardiac pacemaker guidelines.
Kahn AA et al. · 2003
Researchers analysed the association between mobile phone use and the anatomical distribution of glial brain tumours in Irish neurosurgical patients. Fifty mobile phone users and twenty three non-users were identified. Fisher's exact test revealed no statistical significance for glioma location based on handedness in the mobile phone user group and for tumour location in both user and non-user groups.
Haarala C et al. · 2003
Sixty-four subjects (32 men, 32 women) in two independent laboratories performed nine cognitive tasks twice, once with the EMF on and once with it off. Reaction times and accuracy were recorded, and the order of exposure and tasks was counterbalanced across subjects and gender. There were no statistically significant differences in performance between genders or laboratories. The previous results were not replicated, and the researchers concluded that EMF had no effect on reaction times or accuracy.
Dubreuil D, Jay T, Edeline JM. · 2003
Researchers exposed rats head-only to 900 MHz GSM electromagnetic fields at 1 and 3.5 W/kg for 45 minutes and compared performance with sham and control rats. In the first experiment, a slightly improved performance was found at 3.5 W/kg, but this was not seen in the delay task. In the third experiment, exploratory activity showed some effects but recognition memory was unaffected. Overall, the experiments provided no evidence that spatial or non-spatial memory is affected by this exposure.
Cook A, Woodward A, Pearce N, Marshall C. · 2003
Researchers investigated whether trends in tumour incidence rates in New Zealand varied since the introduction of cellular telephones in 1987. The exposure measure was the proportion of cellular telephone subscribers within the national population. They compared trends in tumour rates at anatomical sites receiving high, medium, and low levels of cellular telephone radiation based on dosimetry data. Graphs for high, medium, and low exposure sites showed no significant changes in trend patterns for either gender from 1986 to 1998. Incidence rates for head and neck malignancies, including sites hypothetically receiving the highest radiofrequency radiation, did not change materially after cellular telephone introduction.
Anane R et al. · 2003
Researchers investigated the effects of acute GSM-900 microwave exposure on the clinical parameters of the acute EAE rat model in two independent experiments with habituated and nonhabituated rats. Female Lewis rats were divided into cage control, sham exposed, and two groups exposed at 1.5 or 6.0 W/kg local SAR averaged over the brain using a loop antenna over their heads. EAE was induced with a mixture of myelin basic protein and Mycobacterium tuberculosis. The 21-day exposure at 2 hours per day had no effect on the onset, duration, or termination of the EAE crisis.
Smythe JW, Costall B. · 2003
The study examined the effects of mobile phone exposure on short- and long-term memory in male and female university students. Participants were randomly assigned to no phone exposure, inactive phone exposure, or active phone exposure conditions. They memorized words arranged in a two-dimensional shape for three minutes, completed a 12-minute distraction task, then drew the shape and placed words, and repeated the task one week later. Error scores were analyzed using non-parametric techniques. Males exposed to an active phone made fewer spatial errors than those exposed to an active phone condition, while females were largely unaffected.
Salford LG, Brun AR, Eberhardt JL, Malmgren L, Persson BRR · 2003
Three groups of eight rats each were exposed for two hours to GSM mobile phone electromagnetic fields of different strengths. The researchers found highly significant evidence for neuronal damage in the cortex, hippocampus, and basal ganglia of exposed rats. The study investigated whether pathological leakage across the blood-brain barrier might be combined with damage to neurons.