Finnie JW, Chidlow G, Blumbergs PC, Manavis J, Cai Z · 2009
Researchers exposed pregnant mice to 900 MHz radiofrequency fields at 4 W/kg for 60 minutes daily throughout gestation. Fetal brains were examined for heat shock proteins HSP25, HSP32, and HSP70. No induction of HSP32 or HSP70 was found in any brains, and HSP25 expression was similar in exposed and control groups. The study concluded that whole-gestation exposure did not produce a stress response detectable by HSPs.
Zareen N, Khan MY, Minhas LA. · 2009
Researchers exposed developing chick embryos to different doses of mobile phone induced EMFs by placing a mobile phone in the incubator in silent ringing mode. After 10 or 15 days of incubation, they compared developmental milestones of surviving embryos with a non-exposed subgroup. EMF exposure significantly decreased embryo survivability. Lower EMF doses caused growth retardation, while increasing doses shifted the effect to partial and then definite growth enhancement.
Gul A, Celebi H, Uğraş S. · 2009
Researchers exposed pregnant rats to mobile phones during pregnancy and examined ovarian follicles in their female offspring at 21 days old. The study group had fewer ovarian follicles than the control group. The authors suggest that intrauterine microwave exposure has toxic effects on ovaries.
Mailankot M et al. · 2009
Researchers exposed male albino Wistar rats to RF-EMR from an active GSM mobile phone for one hour daily over 28 days. Exposed rats had significantly reduced sperm motility but no change in total sperm count. RF-EMR exposure also increased lipid peroxidation and decreased glutathione levels in the testis and epididymis. Facial temperature did not change significantly during exposure.
Hässig M, Jud F, Naegeli H, Kupper J, Spiess BM. · 2009
Researchers conducted a cohort study tracking the geographical location of each dam and calf from conception through the fetal period to slaughter, with particular emphasis on the first trimester of gestation (organogenesis). Antioxidant activities of superoxide dismutase, catalase, and glutathione peroxidase were measured in aqueous humor to evaluate redox status. Among 253 calves, 79 (32%) had nuclear cataract and 9 (3.6%) had severe nuclear cataract. Oxidative stress was increased in eyes with cataract, with an odds ratio of 0.80 per kilometer distance from the nearest base station and a 95% confidence interval of 0.62,0.93, and the authors state that it has not been shown that antennas actually affected stress.
Agarwal A et al. · 2009
After liquefaction, neat semen samples were divided into two aliquots, with one exposed to cellular phone radiation in talk mode for 1 hour and the other serving as an unexposed control under identical conditions. Exposed samples showed a significant decrease in sperm motility and viability, an increase in ROS level, and a decrease in ROS-TAC score. Levels of total antioxidant capacity and DNA damage showed no significant differences between exposed and unexposed samples.
Zareen N, Khan MY, Ali Minhas L · 2009
Embryos exposed for 10 post-incubation days showed decreased retinal growth and mild epithelial pigmentation. Extending exposure to 15 post-incubation days reversed growth retardation to enhancement and shifted pigmentation from mild to intense. The authors concluded that mobile phone EMF causes derangement of chicken embryo retinal differentiation. Retinal thickness and epithelial pigmentation grades were statistically compared between control and experimental groups.
Dimbylow PJ, Nagaoka T, Xu XG. · 2009
The study compared foetal specific absorption rate (SAR) across three sets of pregnant female computational models. The models included a 26-week foetal model from the National Institute of Information and Communications Technology, Tokyo, and models at 13, 26, and 38 weeks from Rensselaer Polytechnic Institute. FDTD calculations were performed at a resolution of 2 mm for a plane wave with a vertically aligned electric field incident upon the body from the front, back and two sides from 20 MHz to 3 GHz under isolated conditions. The researchers compared external electric field values required to produce the ICNIRP public exposure localized restriction of 2 W kg(-1) when averaged over 10 g of the foetus with the ICNIRP reference levels.
De Iuliis GN, Newey RJ, King BV, Aitken RJ. · 2009
Researchers exposed purified human spermatozoa in vitro to radio-frequency electromagnetic radiation tuned to 1.8 GHz across a range of specific absorption rates from 0.4 W/kg to 27.5 W/kg. As the SAR increased, sperm motility and vitality were significantly reduced, while mitochondrial reactive oxygen species generation and DNA fragmentation were significantly elevated (P<0.001). The researchers also observed highly significant relationships between SAR, the oxidative DNA damage biomarker 8-OH-dG, and DNA fragmentation after exposure.
Franzellitti S, Valbonesi P, Contin A, Biondi C, Fabbri E. · 2008
Researchers evaluated HSP70 gene and protein expression in human trophoblast HTR-8/SVneo cells after 4 to 24 hours of exposure to 1.8 GHz continuous-wave and GSM signals. Inducible HSP70 protein expression was not modified by any exposure condition. HSP70C transcript levels increased after 24 hours of GSM-217Hz exposure and decreased after 4 and 16 hours of GSM-Talk exposure, while HSP70A, HSP70B, and HSC70 transcripts did not change.
Dasdag S, Akdag MZ, Ulukaya E, Uzunlar AK, Yegin D. · 2008
Apoptosis was assessed by immunohistochemical staining for cleaved caspase-3 in testicular tissue. The exposed group showed no statistically significant difference in apoptosis scores compared to sham and cage control groups.
Yilmaz F, Dasdag S, Akdag MZ, Kilinc N · 2008
Researchers investigated anti-apoptotic bcl-2 protein in rat brain and testes after whole-body exposure to 900 MHz cellular phone radiation. The results showed that 20 minutes of radiation did not alter bcl-2 protein in the brain and testes of rats. The study used two groups of eight Sprague-Dawley rats each, with the experimental group exposed to phones in speech condition for 20 minutes per day for one month and the sham group exposed to turned-off phones. The authors speculated that bcl-2 may not be involved in radiation effects on the brain and testes of rats.
Rezk AY, Abdulqawi K, Mustafa RM, Abo El-Azm TM, Al-Inany H · 2008
Researchers enrolled 90 pregnant women with uncomplicated pregnancies and 30 full-term newborns for the study. Pregnant women were exposed to mobile phone electromagnetic fields in dialing mode for 10 minutes, and fetal and neonatal heart rate and cardiac output were measured. Exposure significantly increased fetal and neonatal heart rate and decreased stroke volume and cardiac output, with these changes becoming less pronounced at higher gestational ages.
Nagaoka T, Saito K, Takahashi M, Ito K, Watanabe S. · 2008
The paper outlines the development of pregnant woman models adjusted to reference physiological characteristics for gestation ages of 13, 18, and 26 weeks. The models are composed of voxels of 2 x 2 x 2 mm³ and include 56 tissue types. Basic specific absorption rate (SAR) characteristics for whole-body RF exposure were calculated using the finite-difference time-domain (FDTD) method.
Chen ZJ, He JL. · 2008
The study aimed to investigate mutagenic, carcinogenic, and teratogenic effects induced by radiofrequency electromagnetic fields from mobile phones. The authors noted that conflicting results exist in publications on these effects. They reported that overwhelming findings do not support the assumption that RF exposure may induce mutagenic, carcinogenic, or teratogenic effects. However, they stated that health effects from low-level RF exposure need further study.
Batellier F, Couty I, Picard D, Brillard JP. · 2008
Researchers exposed fertile chicken eggs to a cell phone in call position over the entire incubation period. Embryo mortality was significantly higher in exposed eggs than in sham eggs in two of four replicates. The additional mortality occurred mainly between days 9 and 12, but a causal relationship with electric field intensity could not be established.
Agarwal A, Deepinder F, Sharma RK, Ranga G, Li J. · 2008
Three hundred sixty-one men undergoing infertility evaluation were divided into four groups based on daily cell phone use: no use, less than 2 hours, 2 to 4 hours, and more than 4 hours. Comparisons of mean sperm count, motility, viability, and normal morphology among the four groups were statistically significant. The decrease in sperm parameters was dependent on the duration of daily exposure to cell phones and independent of the initial semen quality.
Divan HA, Kheifets L, Obel C, Olsen J · 2008
Mothers of 13,159 children completed a follow-up questionnaire reporting cell phone use during pregnancy and the child's current cell phone use. Greater odds ratios for behavioral problems were observed for children with possible prenatal or postnatal exposure to cell phone use. After adjustment for potential confounders, the odds ratio for a higher overall behavioral problems score was 1.80 (95% confidence interval = 1.45–2.23) in children with both prenatal and postnatal exposure. The authors noted that these associations may be noncausal and may be due to unmeasured confounding.
Odaci E, Bas O, Kaplan S · 2008
Researchers investigated the effects of prenatal EMF exposure on the number of granule cells in the dentate gyrus of 4-week-old rats. Pregnant rats in the exposed group were subjected to a 900 MHz EMF for 60 min/day between the first and last days of gestation. The results showed that prenatal EMF exposure caused a decrease in the number of granule cells in the dentate gyrus (P < 0.01).
Hardell L et al. · 2007
A case-control study investigated the risk of testicular cancer in relation to use of cellular and cordless telephones. The analysis included 542 seminoma cases, 346 non-seminoma cases, and 870 controls. For seminoma, odds ratios were 1.2 for analog phones, 1.3 for digital phones, and 1.1 for cordless phones. For non-seminoma, odds ratios were 0.7 for analog phones, 0.9 for digital phones, and 1.0 for cordless phones. There was no dose-response effect and odds ratios did not increase with latency time.
Yan JG, Agresti M, Bruce T, Yan YH, Granlund A, Matloub HS. · 2007
Rats exposed to 6 hours of daily cellular phone emissions for 18 weeks exhibited a significantly higher incidence of sperm cell death than control group rats through chi-squared analysis. Abnormal clumping of sperm cells was present in exposed rats and absent in controls.
Wdowiak A, Wdowiak L, Wiktor H. · 2007
The objective was to determine the effect of cellular phone usage on the fertility of males undergoing marital infertility therapy. The study included 304 men divided into groups: 99 who did not use mobile phones, 157 who used GSM equipment sporadically for 1-2 years, and 48 who regularly used mobile phones for more than 2 years. An increase in the percentage of sperm cells with abnormal morphology was associated with longer duration of exposure to waves emitted by GSM phones. A decrease in the percentage of sperm cells with vital progressive motility was correlated with the frequency of mobile phone use.
Panagopoulos DJ, Chavdoula ED, Nezis IP, Margaritis LH · 2007
Researchers used the TUNEL assay to detect DNA fragmentation in early and mid-oogenesis stages of Drosophila melanogaster. Flies were exposed to GSM 900-MHz or DCS 1800-MHz radiation from a mobile phone for a few minutes daily over the first six days of adult life. Both radiation types induced DNA fragmentation in all cell types of the egg chamber, leading to degeneration of egg chambers. Germarium and stages 7-8 were the most sensitive developmental stages, with germarium even more sensitive than stages 7-8.
Liu XY et al. · 2007
Researchers interviewed 200 women with early spontaneous abortion and age-matched controls and used multivariable logistic regression. In single-factor analysis, higher proportions of watching TV ≥10 hours/week, computer use ≥45 hours/week, using copycat, microwave oven and mobile phone, and proximity to switch rooms ≤50 m and launching towers ≤500 m were found in cases versus controls. After multivariable adjustment, using a microwave oven and mobile phone, exposure to abnormal renovation smell for ≥3 months, emotional stress in early pregnancy, and prior spontaneous abortion remained significantly associated with miscarriage risk. The odds ratios for these risk factors were 2.23 and 4.63.
Guney M, Ozguner F, Oral B, Karahan N, Mungan T. · 2007
Rats were randomly assigned to four groups of eight each, including a control, a sham, a 900 MHz EMR exposure group, and an EMR plus vitamins E and C group, and the EMR groups received 30 minutes per day for 30 days. EMR exposure increased endometrial nitric oxide and malondialdehyde levels and decreased superoxide dismutase, catalase, and glutathione peroxidase activities, while combined vitamins E and C reversed these changes. The EMR group showed diffuse severe apoptosis in endometrial epithelial, glandular, and stromal cells and diffuse eosinophilic leucocyte and lymphocyte infiltration, which were significantly reduced by vitamins E and C.
