Bastide M, Youbibier-Simoa BJ, Lebecq JC, Giaimis J. · 2001
Researchers investigated continuous exposure of chick embryos and young chickens to EMFs from video display units and GSM cell phone radiation, including radiation attenuated by copper gauze. Permanent exposure to VDU EMFs was associated with significantly increased fetal loss (47-68%) and markedly depressed levels of circulating specific antibodies (lgG), corticosterone and melatonin. Under chronic exposure, GSM cell phone radiation was harmful to chick embryos, stressful for healthy mice, and synergistic with cancer by depleting stress hormones in mice. The same pathological results occurred after substantial reduction of microwaves by copper gauze attenuation.
De Roos AJ et al. · 2001
Researchers examined parental occupational exposures to electromagnetic fields and radiation and the incidence of neuroblastoma in offspring. Cases were 538 children diagnosed with neuroblastoma between 1992 and 1994 in the United States or Canada, and age-matched controls were selected by random-digit dialing. Maternal exposure to a broad grouping of sources that produce radiofrequency radiation was associated with an increased incidence of neuroblastoma, with an odds ratio of 2.8 and a 95% confidence interval of 0.9 to 8.7. However, the broad groupings of sources that produce ELF fields, radiofrequency radiation, or ionizing radiation were not associated with neuroblastoma.
Bornhausen M, Scheingraber H · 2000
Nakamura H, Nagase H, Ogino K, Hatta K, Matsuzaki I · 2000
Researchers exposed rats to continuous-wave microwaves at 2 mW/cm² and 2450 MHz for 90 minutes and measured uteroplacental blood flow and hormone levels. Colonic temperature did not change significantly in either virgin or pregnant rats. Microwave exposure decreased uteroplacental blood flow and increased progesterone and PGF2α in pregnant rats but not in virgin rats. Pretreatment with angiotensin II prevented these changes in pregnant rats. Corticosterone increased and estradiol decreased during exposure regardless of pregnancy status or angiotensin II pretreatment.
Dasdag S; Akdag MZ; Ayy ld z O et al. · 2000
Researchers studied the effects of microwaves emitted by cellular phones on peripheral blood parameters and birth weights of rats. The birth weight of offspring in the experimental group was significantly lower than in the sham-exposed group (p < 0.001). No blood parameters differed following exposure, and rectal temperatures showed no significant differences between groups. All parameters investigated were normal in the next generation of rats.
Cobb BL et al. · 2000
Researchers exposed pregnant rats to UWB electromagnetic fields during gestation days 3-18, with some pups also exposed for 10 days after birth, then evaluated offspring for behavioral, functional, and morphological effects. UWB-exposed pups emitted significantly more stress vocalizations than sham-exposed pups, and the medial-to-lateral length of the hippocampus was significantly longer in UWB-exposed pups than in sham-exposed animals. Researchers noted there does not appear to be a unifying physiological or behavioral relationship among the significant differences observed.
Nelson BK, Snyder DL, Shaw PB · 1999
The purpose was to determine if synergistic effects of radiofrequency radiation and 2-methoxyethanol generalize to other chemicals. Rats received salicylic acid at 0, 250, or 350 mg/kg by gavage on gestation day 9 or 13. Rats given salicylic acid on day 9 were exposed to radiofrequency radiation sufficient to maintain colonic temperature at 41 degrees C for 60 minutes or received a sham exposure, while those given salicylic acid on day 13 also received 0 or 100 mg/kg 2-methoxyethanol by gavage. Fetuses were examined for external malformations on gestation day 20.
Nelson BK, Conover DL, Krieg EF Jr, Snyder DL, Edwards RM · 1998
Researchers tested whether environmental temperature changes the interactive developmental toxicity of radiofrequency radiation and 2-methoxyethanol. Environmental temperature affected the specific absorption rate needed to maintain a given colonic temperature but did not affect the interactive developmental toxicity. The results add to evidence that developmental toxicity of radiofrequency radiation is associated with colonic temperature, not with specific absorption rate. Fetuses were examined for external malformations on gestation day 20.
Nakamura et al. · 1998
Researchers exposed pregnant rats to microwaves at 2 mW/cm2, 2450 MHz for 90 minutes and measured natural killer cell activity and beta-endorphin levels. Microwave exposure raised colonic temperature and increased beta-endorphin in blood and anterior pituitary but did not change corticosterone. Naloxone administered before exposure increased natural killer cell activity and beta-endorphin in blood and placenta of pregnant rats.
Nelson BK, Conover DL, Shaw PB, Snyder DL, Edwards RM · 1997
Researchers exposed pregnant rats to radiofrequency radiation that raised colonic temperature to 42.0°C for 10 minutes while administering various doses of 2-methoxyethanol on gestation day 13. Dose-related developmental toxicity from 2-methoxyethanol occurred both with and without the radiation exposure. However, the radiation changed the shape of the dose-effect curve for 2-methoxyethanol.
Magras, IN, Xenos, TD · 1997
Researchers measured RF power densities between 168 nW/cm2 and 1053 nW/cm2 at several locations around an antenna park. Twelve pairs of mice divided into two groups were placed in locations of different power densities and mated five times. The number of newborns per dam decreased progressively until irreversible infertility occurred, but crown-rump length, body weight, and vertebral counts improved.
Nakamura H, Seto T, Nagase H, Yoshida M, Dan S, Ogino K. · 1997
Pregnant rats exposed to microwaves showed a significant reduction in splenic natural killer cell activity, while no such reduction was seen in exposed virgin rats. Corticosterone and ACTH increased, and oestradiol decreased, in both exposed virgin and pregnant rats, while beta-endorphin and progesterone increased significantly only in pregnant rats.
Jensh RP · 1997
This review examined whether chronic prenatal microwave exposure in rats caused adverse effects at birth or alterations in offspring development and growth. Pregnant rats were exposed throughout pregnancy to continuous wave 915 MHz, 2450 MHz, or 6000 MHz radiation at power density levels of 10, 20, or 35 mW/cm2, respectively. Animals exposed to 915 MHz did not exhibit any consistent significant alterations in any of the parameters measured. Offspring exposed to 6000 MHz showed an initial slight but significant retardation in term weight, delayed eye opening, lower weekly weights that recovered by the fifth week, and changes in water T-maze and open field performance.
Kubinyi G, Thuroczy G, Bakos J, Boloni E, Sinay H, Szabo LD, · 1996
Pregnant CFLP mice were exposed to 2.45 GHz microwave radiation for 100 minutes each day throughout gestation in an anechoic chamber. Brain aminoacyl-tRNA synthetase activity decreased significantly after continuous-wave exposure but not after amplitude-modulated exposure. Liver enzyme activity increased after both continuous-wave and amplitude-modulated exposure, while body and organ weights were unaffected.
Yoshida Y et al. · 1995
Researchers exposed pregnant rats to whole-body microwaves at 10 mW/cm2 and 2,450 MHz and measured placental blood flow and five endocrine indicators. Placental blood flow at 45-90 minutes after exposure was significantly decreased in exposed rats. Microwave exposure increased corticosterone and decreased estradiol regardless of angiotensin II pretreatment, increased progesterone and prostaglandin F2 alpha without pretreatment, and did not change prostaglandin E2. Pretreatment with angiotensin II increased placental blood flow at 15 and 30 minutes, but this effect was absent in microwave-exposed rats.
Nelson BK et al. · 1994
Researchers exposed rats to RF radiation that maintained colonic temperature at 42.0 degrees C for 0, 10, 20, or 30 min and to 2ME at doses of 0, 75, 100, 125, or 150 mg/kg on gestation days 9 or 13. Fetuses were examined on gestation day 20 for external, skeletal, and visceral malformations. Synergistic effects were observed for some treatment combinations but not others, with highly significant effects on gestation day 13 but little effect on day 9. Statistical analyses showed no global synergistic effect but evidence of synergism at intermediate dose levels.
Guberan E et al. · 1994
Researchers mailed a questionnaire to 2846 female Swiss physiotherapists and analyzed 1781 pregnancies. The gender ratio was 107 for 508 pregnancies exposed to shortwave radiation and 101 for 1273 unexposed pregnancies. There was no trend in gender ratio with increasing intensity or duration of exposure. Low birthweight prevalence was not related to exposure for either boys or girls. The findings of the Danish study could not be confirmed.
Ouellet-Hellstrom R, Stewart WF · 1993
Researchers mailed questionnaires to 42,403 physical therapists in 1989 and used a nested case-control design with 1,753 miscarriage cases matched to 1,753 controls. A pregnancy was considered exposed if the mother reported using microwave or shortwave diathermy in the six months before or during the first trimester. Microwave use was associated with increased miscarriage odds (OR 1.28, 95% CI 1.02-1.59) with a dose-response trend, while shortwave diathermy was not associated (OR 1.07, 95% CI 0.91-1.24).
Fukui Y, Hoshino K, Inouye M, Kameyama Y · 1992
Researchers exposed pregnant mice to 2.45 GHz microwave radiation for 15 or 20 minutes on day 13 of gestation. Pyknotic cell incidence in the ventricular zone was 1.83% after 15 minutes and 3.06% after 20 minutes of microwave exposure. Microwave radiation for 20 minutes produced effects comparable to immersion in 42°C hot water for 15 minutes. Brain weight was significantly lower and neuron density higher in the 20-minute exposure group compared to controls. The researchers concluded that microwave radiation at the tested dose mainly has a thermal effect.
Larsen AI · 1991
Researchers conducted a case-referent study using a cohort of Danish physiotherapists linked to national pregnancy registers to assess the relation between high-frequency electromagnetic radiation exposure and congenital malformations. Exposure during the first month of pregnancy was assessed through blinded telephone interviews without knowledge of case status. No statistically significant associations were found between pregnancy outcome and high-frequency electromagnetic radiation exposure (odds ratio 1.7, 95% confidence interval 0.6-4.3).
Nelson BK et al. · 1991
The exploratory study aimed to determine whether concurrent exposure to RF radiation and 2-methoxyethanol enhances developmental toxicity in rats. In the primary study, pregnant rats were exposed to RF radiation sufficient to raise rectal temperature to 42.0°C for 30 minutes and given 150 mg/kg 2-methoxyethanol by gavage, and the combination raised mean fetal malformations per litter to 76% from 14% with 2ME alone and 30% with RF alone. The severity of malformations also increased with the combination, scoring 6 on a relative severity scale compared with less than 1 for 2ME alone and 3 for RF alone.
