Mohler E et al. · 2010
Researchers assessed self-reported sleep disturbances and daytime sleepiness in a random sample of 1,375 residents of Basel, Switzerland. Environmental far-field RF EMF exposure was predicted for each individual using a validated prediction model, and mobile and cordless phone use were also considered. Multivariable regression models adjusted for confounders showed no association between far-field RF EMF exposure and sleep disturbances or excessive daytime sleepiness. The 10% most exposed participants had an estimated risk for sleep disturbances of 1.11 (95% CI: 0.50 to 2.44) and for excessive daytime sleepiness of 0.58 (95% CI: 0.31 to 1.05). Neither mobile phone use nor cordless phone use was associated with decreased sleep quality.
Danker-Hopfe H, Dorn H, Bornkessel C, Sauter C. · 2010
Researchers conducted a double-blind, sham-controlled, randomized cross-over study with 397 residents exposed to GSM base station signals and sham exposure at home for 12 nights. No significant differences in objective or subjective sleep measures were found between real and sham exposure conditions. During sham exposure nights, participants with concerns about health risks from base stations had significantly worse sleep efficiency, wake after sleep onset, and subjective sleep latency than those without concerns. The authors concluded that EMF from base stations did not affect sleep quality, but the presence of base stations themselves may negatively impact sleep.
Angelone LM, Bit-Babik G, Chou CK. · 2010
Researchers performed a finite-difference time-domain simulation of a human head model with EEG electrodes and leads exposed to RF sources at 915 MHz and 1748 MHz. Whole-head and peak 10-g average SAR changed by less than 20% with leads present, and peak SAR values remained below ICNIRP and IEEE limits. However, a volumetric assessment revealed a two-order-of-magnitude increase in single-voxel power absorption in the epidermis and a 40-fold increase in the brain when metallic leads were used with a 915 MHz mobile phone.
Vecchio F et al. · 2010
Researchers recorded eyes-closed resting EEG data from 16 healthy elderly subjects and 5 young subjects during GSM-on and GSM-off conditions lasting 45 minutes each. Spectral coherence measured inter-hemispheric synchronization across delta, theta, and alpha frequency bands. Elderly subjects showed a statistically significant increment of inter-hemispheric coherence of frontal and temporal alpha rhythms during the GSM condition compared to young subjects. The results suggest GSM-EMFs affect inter-hemispheric synchronization of alpha EEG rhythms as a function of physiological aging.
Vorobyov V, Janać B, Pesić V, Prolić Z. · 2010
Researchers studied EEG in 10 freely moving rats with electrodes implanted in the cortex and dorsomedial hypothalamus over five consecutive days. Rats were exposed to ELF-MW (915 MHz, 20-ms pulse duration, approximately 0.3 mW/cm(2), 4 Hz) intermittently (1-min 'On', 1-min 'Off') for 10 min several times per day. Baseline EEG showed dominant activity in the 3.2-6.0 Hz and 17.8-30.5 Hz ranges in the cortex, and in the 6.0-17.8 Hz range in the hypothalamus. ELF-MW exposure increased beta(2) activity in the hypothalamus more than in the cortex, significantly reducing the initial cortical-hypothalamic EEG imbalance. A cumulative effect was observed across repeated exposures.
Danker-Hopfe H, Dorn H, Bahr A, Anderer P, Sauter C. · 2010
Carrubba S, Frilot C 2nd, Chesson AL Jr, Marino AA · 2010
Researchers recorded EEGs from six standard locations in 20 volunteers to detect brain potentials triggered by a pulse of the type produced by mobile phones. Evoked potentials having the expected latency were found in 90% of the volunteers, as assessed using a nonlinear method of EEG analysis. Evoked potentials were not detected when the EEG was analyzed using time averaging. The possibility of systematic error was excluded by sham-exposure analyses.
Croft RJ et al. · 2010
Researchers tested whether adolescents and the elderly are more sensitive to mobile phone-related bioeffects than young adults, using both 2G GSM and 3G W-CDMA exposures. Resting alpha activity in the 8-12 Hz band of the EEG was recorded and compared between conditions in a double-blind crossover design, with each participant receiving sham, 2G, and 3G exposures separated by at least 4 days. Young adults showed greater alpha activity in the 2G condition compared to sham, but no effect was found in adolescents or the elderly, and 3G exposure produced no effect in any group.
Xu S et al. · 2010
Researchers exposed primary cultured cortical neurons to pulsed radiofrequency electromagnetic fields at 1800 MHz modulated by 217 Hz at an average specific absorption rate of 2 W/kg. At 24 hours after exposure, researchers found a significant increase in levels of 8-hydroxyguanine, a common biomarker of DNA oxidative damage, in the mitochondria of neurons. The copy number of mitochondrial DNA and the levels of mitochondrial RNA transcripts showed an obvious reduction after RF exposure. Each of these mitochondrial DNA disturbances could be reversed by pretreatment with melatonin.
Lipping T et al. · 2009
Eleven pigs were anaesthetized to a burst-suppression EEG level and exposed to a GSM mobile phone signal at 890 MHz. In phase I, EMF stimulation was randomly switched on and off to study the relation between EEG bursts and EMF onsets and endpoints. In phase II, continuous RF stimulation at 31 W/kg was applied for 10 minutes while ECG, EEG, and subcutaneous temperature were recorded. No correlation between exposure and EEG burst occurrences was observed in phase I, and no significant EEG changes were found in phase II. Subcutaneous temperature increased by 1.6°C and heart rate by 14.2 bpm on average during the 10-minute exposure periods.
Berg-Beckhoff G et al. · 2009
Researchers conducted a cross-sectional study in 2006 with 3526 participants living mainly in urban regions to test whether low-level RF-EMF from mobile phone base stations was related to health disturbances. Exposure was assessed with a dosimeter measuring different RF-EMF frequencies, and health outcomes were collected via postal questionnaires on sleep disturbances, headaches, health complaints, and mental and physical health. No differences in median health scores were found between exposed and non-exposed participants, and measured RF-EMFs were not associated with adverse health effects.
Naziroğlu M, Gümral N. · 2009
Researchers divided thirty rats into five groups to study the effects of 2.45 GHz electromagnetic radiation on the brain's antioxidant system and EEG records. Exposed rats received 2.45 GHz electromagnetic radiation for 60 minutes per day for 28 days, after which EEG records and brain cortex samples were collected. Brain cortex concentrations of vitamin A, vitamin C, and vitamin E were lower in the exposed group than in controls, though these concentrations were increased by selenium and L-carnitine supplementation. L-carnitine appeared to have a more protective effect on vitamin concentrations than selenium.
López-Martín E et al. · 2009
Researchers studied whether pulse-modulated GSM radiation had different effects on brain activity than an unmodulated signal of the same wavelength, and examined c-Fos expression in seizure-related brain circuits. Rats made seizure-prone with picrotoxin and then exposed to GSM radiation showed differences in clinical and EEG signs and in c-Fos expression compared with picrotoxin-treated rats exposed to unmodulated radiation. The most marked effects of GSM radiation on c-Fos expression in picrotoxin-treated rats were observed in limbic structures, olfactory cortex areas, subcortical areas, the dentate gyrus, and the central lateral nucleus of the thalamic intralaminar nucleus group. Neither radiation treatment caused tissue heating, so the researchers ruled out thermal effects.
Stefanics G, Thuróczy G, Kellényi L, Hernádi I · 2008
Before and after exposure, subjects heard tone bursts while EEG was recorded and counted target tones. No significant effects were found on the amplitude or latency of N100, N200, P200, or P300 components. Early evoked gamma activity was also insensitive to the UMTS RF exposure.
Kleinlogel H et al. · 2008
Researchers tested 1950 MHz UMTS at SAR 0.1 and 1 W/kg and pulsed 900 MHz GSM at 1 W/kg on well-being and vigilance-controlled resting EEG in 15 healthy right-handed subjects. The study used a double-blind randomised crossover design. Neither UMTS nor GSM exposure produced significant changes in measured parameters compared to sham exposure. The results did not give evidence for a deleterious effect of the EMF on normal healthy mobile phone users.
Khan MM. · 2008
Researchers surveyed medical students using a questionnaire about mobile phone use and health complaints. The response rate was 86.6% with 286 of 330 forms completed. Most students (83.57%) had some knowledge about adverse effects of mobile phone use. Daily mobile phone use was less than 30 minutes for 55.94% of students, 30-60 minutes for 27.97%, 60-90 minutes for 11.53%, and more than 90 minutes for 4.54%. Reported symptoms included headache (16.08%), fatigue (24.48%), impaired concentration (34.27%), memory disturbances (40.56%), sleeplessness (38.8%), hearing problems (23.07%), facial dermatitis (16.78%), and a sensation of warmth in the ear area (28.32%); 44.4% of the 286 subjects linked their symptoms to mobile phone use.
Perentos N, Croft RJ, McKenzie RJ, Cvetkovic D, Cosic I. · 2008
Researchers investigated the effect of GSM-like ELF radiation on the alpha band of the human resting EEG. The study used a fully counterbalanced, double-blind, cross-over design with 72 healthy volunteers. A decrease in the alpha frequency band was observed during 20 minutes of ELF exposure in the exposed hemisphere only.
Hountala CD et al. · 2008
Researchers introduced spectral power coherence as a measure of coordination among four EEG frequency bands at a specific brain location. They found that delta rhythm contributes less to this coordination than theta, alpha, and beta rhythms. Gender differences in overall spectral power coherence were observed without radiation, but these differences disappeared during 900 MHz exposure and reversed during 1800 MHz exposure. The measure was calculated from pre-stimulus EEG during an auditory memory task under 900 MHz and 1800 MHz electromagnetic field conditions.
Hinrikus H, Bachmann M, Lass J, Tomson R, Tuulik V. · 2008
Thirteen healthy volunteers were exposed to 450 MHz microwaves pulse-modulated at frequencies of 7, 14 and 21 Hz to evaluate effects on electroencephalographic (EEG) rhythms. Modulated microwaves caused an average increase in EEG alpha power of 17% and beta power of 7%, while the theta rhythm remained unaffected. Increases in EEG alpha and beta power were statistically significant during the first 30 seconds of exposure at modulation frequencies of 14 and 21 Hz, but no enhancement occurred at 7 Hz. The researchers also found differences in individual sensitivity to exposure, with increases in EEG beta power appearing statistically significant in four subjects.
Hinrikus H, Bachmann M, Lass J, Karai D, Tuulik V. · 2008
Sokolovic D et al. · 2008
Researchers exposed Wistar rats to microwave radiation from a mobile test phone for 20, 40, and 60 days to evaluate oxidative stress in brain tissue and whether melatonin could reduce it. Exposure led to a significant increase in malondialdehyde and carbonyl group concentrations in brain tissue, along with decreased catalase activity and increased xanthine oxidase activity. Melatonin treatment significantly prevented the rise in MDA content and xanthine oxidase activity after 40 days of exposure, but was unable to prevent the decrease in catalase activity or the increase in carbonyl group content.
Croft RJ et al. · 2008
Researchers tested 120 healthy participants in a double-blind, counterbalanced crossover design, with each person receiving a 30-minute active and a 30-minute sham exposure one week apart while EEG data were recorded. The purpose of the study was to test one of the strongest findings in the literature, that of increased alpha power in response to MP-type radiation. Overall alpha power was enhanced during exposure, with the effect larger at sites on the same side as the exposure source than on the opposite side over posterior regions. After exposure ended, no overall change to alpha power was observed, though there was less alpha power contralateral to the exposure source relative to the ipsilateral side.
Perentos N, Croft RJ, McKenzie RJ, Cvetkovic D, Cosic I · 2007
Researchers used a fully counterbalanced cross-over design with 12 participants to test mobile phone-like RF exposure effects on EEG. Exposures lasted 15 minutes using a dipole antenna more closely resembling a real GSM handset.
Fritzer G et al. · 2007
Krause CM, Pesonen M, Haarala Bjornberg C, Hamalainen H. · 2007
Researchers recruited two groups of 36 male participants each, one performing an auditory memory task and the other a visual working memory task under six exposure conditions. The study aimed to partially replicate earlier work and investigate effects of mobile phone EMF on event-related desynchronisation/synchronisation EEG responses during cognitive processing. EMF exposure produced modest effects on alpha band oscillatory responses but no effects on behavioural measures. The EEG effects were varying, unsystematic, and inconsistent with previous reports.
