Vecchio F et al. · 2007
Ten subjects underwent two EEG recordings separated by one week in a crossover double-blind paradigm. The mobile phone was held on the left side of the head by a modified helmet. Each session lasted 45 minutes with real GSM exposure in one session and sham in the other. GSM stimulation modulated interhemispheric frontal and temporal coherence at alpha2 and alpha3 bands compared to sham.
Parazzini M et al. · 2007
Researchers exposed 26 healthy young volunteers to 900 MHz GSM phone radiation and sham exposure in separate double-blind sessions. A rest-to-stand protocol assessed autonomic nervous system function during rest and after sympathetic activation. No statistically significant effect of EMF exposure was found on the main RR mean or most other heart rate variability parameters. A weak interaction between some time and frequency domain HRV parameters and RF exposure was observed around the sympathetic response to standing.
Abdel-Rassoul G et al. · 2007
A cross-sectional study enrolled 85 residents living near a mobile phone base station in Egypt and 80 matched controls. Exposed residents reported significantly higher rates of headache, memory changes, dizziness, tremors, depressive symptoms, and sleep disturbance than controls. On neurobehavioral testing, exposed residents performed worse on a test of attention and short-term auditory memory but better on tests of visuomotor speed and attention. Residents living opposite the station performed worse on a problem-solving test than those living under the station. Measured radiofrequency radiation levels were below the allowable standard.
Crouzier D et al. · 2007
Researchers exposed freely moving rats for 24 hours to a 1.8 GHz GSM radiofrequency signal at low power density. The study tracked acetylcholine release in the hippocampus, EEG, EMG, and subcutaneous temperature, and also analyzed brain lipid extracts using NMR after the animals were sacrificed. No significant changes in any measured parameter were observed under radiofrequency exposure, and the NMR study also failed to show any effect.
Bachmann M et al. · 2007
Researchers studied how the human brain's bioelectrical activity adapted to low-level microwave exposure in a group of 14 healthy volunteers. The volunteers were exposed to 450 MHz microwave radiation modulated at 40 Hz frequencies, with a field power density at the scalp of 0.16 mW/cm(2). Results showed that an initial increase in EEG power was compensated and even overcompensated, with adaptation effects apparent in alpha and beta rhythms.
Regel SJ et al. · 2007
Researchers exposed the heads of 15 healthy male subjects for 30 min prior to sleep to a pulse-modulated EMF signal at different intensities or a sham condition, in a double-blind, crossover design. The active exposure levels used peak spatial specific absorption rates of 0.2 W kg–1 and 5 W kg–1. Sleep EEG analysis showed a dose-dependent increase of power in the spindle frequency range in non-REM sleep, while sleep architecture was not affected. Reaction speed slowed with increasing field intensity in the 1-back task, but accuracy in the CRT and N-back tasks was not affected in a dose-dependent manner.
Hung CS, Anderson C, Horne JA, McEvoy P · 2007
Researchers exposed 10 healthy young adults to talk, listen, standby, or sham signal modes for 30 minutes, then gave them a 90-minute sleep opportunity. Sleep latency after talk mode was markedly and significantly delayed beyond listen and sham modes. This condition effect was also evident in 1–4 Hz EEG frontal power, a frequency range described as particularly sensitive to sleep onset. There was no condition effect for subjective sleepiness.
Sukhotina I, Streckert JR, Bitz AK, Hansen VW, Lerchl A · 2006
Researchers exposed isolated pineal glands from Djungarian hamsters to 1800 MHz continuous wave or GSM-modulated signals at SAR levels of 8, 80, 800, and 2700 mW/kg for 7 hours. At 800 mW/kg SAR both signal types significantly enhanced melatonin release, but at 2700 mW/kg SAR continuous wave elevated melatonin while GSM-modulated exposure suppressed it. The authors concluded that the data do not support the melatonin hypothesis that nonthermal radiofrequency exposure suppresses melatonin synthesis.
Hamblin DL, Croft RJ, Wood AW, Stough C, Spong J. · 2006
Researchers tested 120 participants in a double-blind, counterbalanced, crossover design with two sessions one week apart. In both sessions, participants performed auditory and visual oddball tasks while EEG was recorded with a mobile phone set to sham exposure mounted over the temporal region, and then performed the same tasks while the handset was set to active or sham. No significant differences were found between exposure conditions for any ERP component or reaction time.
Wood A, Loughran S, Stough C · 2006
In a double-blind cross-over study, 55 adult volunteers were exposed to mobile phone emissions for 30 minutes at 0.25 W average power or sham exposure on successive nights. Urine was collected before bed and upon waking, and melatonin output was estimated from 6-sulphatoxymelatonin concentrations, urine volume, and creatinine. Total melatonin metabolite output did not differ between active and sham exposure, but pre-bedtime output normalized to creatinine was significantly lower after active exposure.
Krause CM et al. · 2006
Researchers collected EEG data from 15 children aged 10 to 14 years while they performed an auditory memory task with and without exposure to a 902 MHz mobile phone in counterbalanced order. During memory encoding, the active mobile phone modulated event-related desynchronization and synchronization responses in the approximately 4 to 8 Hz EEG frequencies. During recognition, the active mobile phone transformed brain oscillatory responses in the approximately 4 to 8 Hz and approximately 15 Hz frequencies.
Faucon G, Le Bouquin Jeannes R, Maby E. · 2006
Nine healthy subjects and six temporal epileptic patients were exposed to radiofrequencies emitted by a GSM mobile phone while EEG signals were recorded with surface electrodes. For healthy subjects, EEG spectral energy decreased on the studied frequency band [0-40 Hz] and more precisely on occipital electrodes for the alpha-band. For epileptic patients, modifications were demonstrated by an increase of the power spectral density of the EEG signal. The authors noted that these biological effects on the EEG are not sufficient to put forward an electrophysiological hypothesis.
Koylu H, Mollaoglu H, Ozguner F, Nazyroglu M, Delibab N. · 2006
Twenty-eight Sprague-Dawley male rats were randomly divided into three groups: sham control, 900-MHz microwave exposure, and microwave exposure with melatonin treatment. Microwave exposure increased lipid peroxidation in both the brain cortex and hippocampus compared to controls. Melatonin administration decreased lipid peroxidation in the hippocampus but did not affect cortex levels.
Paulraj R, Behari J · 2006
The control group was sham irradiated. The study revealed a statistically significant decrease in PKC activity in the hippocampus compared to the rest of the brain and controls. Electron microscopy showed an increase in glial cell population in the exposed group.
Hutter HP, Moshammer H, Wallner P, Kundi M. · 2006
Researchers conducted a cross-sectional study of 365 randomly selected inhabitants living near 10 mobile phone base stations in urban and rural areas. High-frequency electromagnetic field strength was measured in the bedrooms of 336 households, and several cognitive tests, wellbeing, and sleep quality were also assessed. Total HF-EMF exposure was far below recommended levels, with a maximum of 4.1 mW/m2, and average power density was 0.05 mW/m2 in the rural area and 0.02 mW/m2 in the urban area. Some symptoms showed a significant relation to measured power density, headaches most strongly, while sleep quality showed no significant effect.
Bachmann M et al. · 2006
Researchers applied three different EEG analysis methods to detect changes caused by microwave exposure in healthy volunteers. Volunteers were exposed to 450 MHz microwave radiation modulated at several different frequencies, with a field power density of 0.16 mW/cm2 at the scalp. Statistically significant changes in EEG rhythms energy and dynamics were found in between 12% and 30% of subjects.
Koyu A et al. · 2005
Researchers studied the effects of 900 MHz and 1800 MHz EMF on nocturnal serum melatonin in adult male Sprague-Dawley rats exposed for 30 minutes per day, five days per week for four weeks. Serum melatonin concentrations were measured at 12:00 pm using a radioimmunoassay method. No statistically significant differences in melatonin levels were found between the 900 MHz exposed group and the sham group, nor between the 1800 MHz exposed group and the sham group.
Iudice A et al. · 2005
Twenty-three young healthy participants completed a 10 km simulated drive under four counterbalanced conditions: alcohol alone, alcohol with 19 h wakefulness, alcohol with 24 h wakefulness, and sober. The combination of alcohol and 24 h wakefulness produced the highest driving impairment, significantly greater than alcohol alone. Alcohol with 19 h wakefulness significantly affected only the time-to-collision measure, while alcohol alone in rested conditions did not significantly change any study measure.
Green AC et al. · 2005
Intracellular calcium concentration ([Ca(2 +) ](i)) was measured in cultured rat cerebellar granule cells and cardiac myocytes during exposure to TETRA fields (380.8875 MHz pulse modulated at 17.6 Hz, 25% duty cycle). Granule cells exposed at specific absorption rates (SARs) of 5, 10, 20, 50 or 400 mW x kg(-1) showed no significant changes in resting [Ca(2 +) ](i). Exposure to TETRA (50 or 400 mW x kg(-1)) had no significant effect on either the rate or amplitude of spontaneous Ca(2 +) transients in cardiac myocytes. Overall, these results showed no evidence of any consistent or biologically relevant effect of TETRA fields on [Ca(2 + )](i) in granule cells and cardiac myocytes at any of the SAR tested.
Besset A, Espa F, Dauvilliers Y, Billiard M, de Seze R. · 2005
The study investigated the effects of daily exposure to GSM 900 type MP on cognitive function. Fifty-five subjects were divided into two groups matched for age, gender, and IQ. The double-blind study lasted 45 days with baseline, exposure, and recovery periods.
Loughran SP et al. · 2005
Researchers examined whether sleep architecture is sensitive to electromagnetic fields from digital mobile phone handsets. Fifty participants were exposed to electromagnetic fields for 30 minutes before sleep. Exposure decreased rapid eye movement sleep latency and increased electroencephalogram spectral power in the 11.5-12.25 Hz range during the initial part of sleep. The authors concluded that mobile phone exposure before sleep may promote rapid eye movement sleep and modify the sleep electroencephalogram in the first non-rapid eye movement sleep period.
Curcio G et al. · 2005
Researchers recorded resting EEG from 20 healthy subjects to study the effect of mobile phone EMF on waking brain activity. Subjects were randomly assigned to two groups and exposed double-blind to a 902.40 MHz signal modulated at 217 Hz with 0.25 W average power before or during EEG recording. Real exposure influenced alpha band spectral power in some bins compared to baseline and sham, with a greater effect when the EMF was on during recording. The authors concluded that pulsed high-frequency EMF can affect normal brain functioning, but no health effect conclusions were drawn.
Vangelova KK, Israel MS. · 2005
Researchers measured urinary 6-sulphatoxymelatonin and three stress hormones in 36 male operators working fast-rotating extended shifts under radiofrequency electromagnetic radiation. Exposure levels were high for broadcasting station operators, low for TV station operators, and very low for satellite station operators. Radiofrequency EMR had no effect on the typical diurnal pattern of 6-sulphatoxymelatonin. High-level exposure significantly increased excretion rates of cortisol, adrenaline, and noradrenaline, while low-level exposure changes were not significant. The 24-hour excretion of cortisol and noradrenaline correlated with time-weighted average exposure measures.
Bachmann M, Kalda J, Lass J, Tuulik V, Säkki M, Hinrikus H. · 2005
Researchers exposed 23 healthy volunteers to a 450 MHz microwave field with 7 Hz frequency on-off modulation, with a field power density of 0.16 mW cm(-2) at the scalp. The study compared traditional spectral analysis and a new non-linear method called analysis of the length distribution of low-variability periods to detect EEG changes from microwave exposure. The non-linear method detected a significant effect in six exposed subjects, while spectral analysis found a significant result for only one subject.
Krause CM et al. · 2004
Researchers conducted a double-blind study in which subjects performed a memory task with and without exposure to a digital 902 MHz field. All eight significant EEG changes from the earlier study were not significant in this replication. The effect of EMF on incorrect answers was inconsistent, with a significant increase in errors observed in this study but not in the earlier one.
