6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.
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Brain & Nervous System

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Key Finding: 83% of 1,950 primary studies on brain & nervous system found biological effects from EMF exposure.

Of 1,950 studies examining brain & nervous system, 83% found measurable biological effects from EMF exposure.

Lowest Documented Effect

Research found effects on brain & nervous system at exposures as low as:

Study Exposure Level in ContextStudy Exposure Level in Context4.3 × 10⁻⁵ mGExtreme Concern - 5 mGFCC Limit - 2,000 mGEffects documented below the Building Biology "No Concern" threshold (0.2 mG)FCC limit is 46.5 million times higher than this level

Research Overview

  • -When you review the peer-reviewed literature on electromagnetic field exposure and brain function, the numbers tell a compelling story: 84% of the 2,753 studies examining this relationship have documented measurable effects.
  • -This isn't a fringe concern or preliminary finding.
  • -This is the dominant scientific picture, and it deserves your attention.

When you review the peer-reviewed literature on electromagnetic field exposure and brain function, the numbers tell a compelling story: 84% of the 2,753 studies examining this relationship have documented measurable effects. This isn't a fringe concern or preliminary finding. This is the dominant scientific picture, and it deserves your attention. The documented effects span multiple systems within your nervous system.

Of 2,753 studies examining EMF effects on the brain and nervous system, approximately 84 percent found measurable biological effects.

The scientific evidence demonstrates that radiofrequency electromagnetic fields from mobile phones and wireless devices produce measurable effects on nervous system function and cellular processes in the brain.

Source: BioInitiative Working Group. BioInitiative Report: A Rationale for Biologically-based Public Exposure Standards for Electromagnetic Radiation. Edited by Cindy Sage and David O. Carpenter, BioInitiative, 2012, updated 2020. www.bioinitiative.org

Research Statistics by EMF Type

EMF TypeStudiesShowing EffectsPercentage
ELF22920891.00%
RF30522272.00%

Source: Dr. Henry Lai research database

Showing 2,030 studies

Dialling and driving: factors influencing intentions to use a mobile phone while driving.

Walsh SP, White KM, Hyde MK, Watson B. · 2008

Attitudes consistently predicted intentions to drive while using a mobile phone, and pressure from significant others also determined some phone use intentions. Perceptions of control had less support as a predictor, and risk was not generally predictive of safer driving intentions. Different factors influenced each form of mobile phone use while driving, suggesting a multi-strategy approach is needed. The researchers examined predictors for calling and text messaging in four scenarios varying vehicle speed and time pressure.

Use of wireless telephones and self-reported health symptoms: a population-based study among Swedish adolescents aged 15-19 years.

Soderqvist F, Carlberg M, Hardell L. · 2008

The aim of the study was to assess wireless phone use and its relation to explanatory factors and self-reported health symptoms. A postal questionnaire with 27 questions and 75 items was sent to 2000 Swedish adolescents aged 15-19 years selected from the population registry using a stratified sampling scheme, and 63.5% of the study subjects answered it. Most participants reported access to a mobile phone (99.6%) and use increased with age; 55.6% of 15-year-olds and 82.2% of 19-year-olds were regular users, girls generally reported more frequent use than boys, and watching TV increased the odds ratio for wireless phone use adjusted for age and gender. Regular users of wireless phones had health symptoms more often and reported poorer perceived health than less frequent users.

Chronic non-thermal exposure of modulated 2450 MHz microwave radiation alters thyroid hormones and behavior of male rats.

Sinha RK · 2008

Researchers exposed male rats to 2450 MHz microwave radiation and assessed thyroid hormones and behavior. Exposed rats showed hyperactivity and aggression, with significant changes in open-field and elevated plus-maze tests. Thyroid hormone levels changed, with T3 decreasing and T4 increasing, correlating with behavioral changes.

Psychological factors associated with self-reported sensitivity to mobile phones.

Rubin GJ, Cleare AJ, Wessely S · 2008

Fifty-two people reporting sensitivity to mobile phones, 19 reporting both mobile phone sensitivity and electrosensitivity, and 60 nonsensitive controls completed a questionnaire. Perceived sensitivity was linked to using a mobile phone mainly for work (3% of controls, 13% of mobile-phone-sensitive, 21% of electrosensitivity) and to greater modern health worries about radiation (mean scores 2.0, 2.7, and 4.0 on a 1–5 scale). The electrosensitivity group reported greater depression, more worries about tainted food and toxic interventions, worse general health, and more medically unexplained syndromes, with no differences in psychiatric cases.

Cognitive and neurobiological alterations in electromagnetic hypersensitive patients: results of a case-control study.

Landgrebe M et al. · 2008

Researchers conducted a case-control study with 89 electromagnetic hypersensitive patients and 107 matched controls. They assessed health status, EMF-specific cognitions, perception thresholds, and cortical excitability using questionnaires and transcranial magnetic stimulation. Discrimination ability was significantly reduced in the hypersensitive group, while perception thresholds for real magnetic pulses were similar between groups. Intra-cortical facilitation was decreased in younger hypersensitive patients and increased in older hypersensitive patients. EMF-related cognitions such as rumination and symptom intolerance differentiated the hypersensitive patients from controls.

Adverse effects of excessive mobile phone use.

Khan MM. · 2008

Researchers surveyed medical students using a questionnaire about mobile phone use and health complaints. The response rate was 86.6% with 286 of 330 forms completed. Most students (83.57%) had some knowledge about adverse effects of mobile phone use. Daily mobile phone use was less than 30 minutes for 55.94% of students, 30-60 minutes for 27.97%, 60-90 minutes for 11.53%, and more than 90 minutes for 4.54%. Reported symptoms included headache (16.08%), fatigue (24.48%), impaired concentration (34.27%), memory disturbances (40.56%), sleeplessness (38.8%), hearing problems (23.07%), facial dermatitis (16.78%), and a sensation of warmth in the ear area (28.32%); 44.4% of the 286 subjects linked their symptoms to mobile phone use.

Source of funding and results of studies of health effects of mobile phone use: systematic review of experimental studies.

Huss A et al. · 2008

Researchers conducted a systematic review of 59 controlled-exposure studies of radiofrequency radiation with health-related outcomes. Industry-funded studies reported the most outcomes but had the lowest odds of a statistically significant association. The association persisted after adjusting for number of outcomes, study quality, and other factors.

Cancer & Tumors174 citations

Meta-analysis of long-term mobile phone use and the association with brain tumours.

Hardell L, Carlberg M, Söderqvist F, Hansson Mild K. · 2008

Researchers evaluated long-term mobile phone use and brain tumour risk in published case-control studies. Ten glioma studies showed an overall odds ratio of 0.9, but a latency of ten years or more gave an odds ratio of 1.2, and ipsilateral use gave an odds ratio of 2.0. Nine acoustic neuroma studies gave an overall odds ratio of 0.9, rising to 1.3 with ten-year latency and 2.4 for ipsilateral use. Seven meningioma studies yielded an overall odds ratio of 0.8, with ten-year latency giving 1.3 and ipsilateral use 1.7.

Distribution of RF energy emitted by mobile phones in anatomical structures of the brain.

Cardis E et al. · 2008

Most energy (97-99%) appears to be absorbed in the brain hemisphere on the side where the phone is used, mainly (50-60%) in the temporal lobe. The average relative SAR is highest in the temporal lobe (6-15% of peak SAR) and cerebellum (2-10%), and decreases very rapidly with increasing depth, particularly at higher frequencies. The SAR distribution appears to be fairly similar across phone models, between older and newer phones, and between phones with different antenna types and positions.

A meta-analysis for neurobehavioral effects due to electromagnetic field exposure emitted by GSM mobile phones.

Barth A et al. · 2008

Researchers carried out a meta-analysis on 19 experimental studies. Ten of the 19 studies met minimum requirements such as blind design and reported means and standard deviations. Attention measured by the subtraction task seems to be affected in regard to decreased reaction time. Working memory measured by the N-back test seems to be affected: 0-back target response time is lower under exposure, 2-back target response time increases, and the number of errors on 2-back non-targets appears to be higher under exposure. The meta-analysis compared exposed with non-exposed subjects assuming a common population effect.

Cardiovascular100 citations

The influence of the call with a mobile phone on heart rate variability parameters in healthy volunteers.

Andrzejak R et al. · 2008

Researchers recorded ECG Holter monitoring in 32 healthy students before, during, and after a mobile phone call in the morning while seated. During the call, time-domain HRV parameters SDNN and SDANN increased significantly, and frequency-domain components VLF, LF, and HF were highest while LF/HF ratio was lowest. The authors concluded that the call may alter autonomic balance, though electromagnetic field effects could not be separated from the influence of speaking.

The effect of GSM-like ELF radiation on the alpha band of the human resting EEG.

Perentos N, Croft RJ, McKenzie RJ, Cvetkovic D, Cosic I. · 2008

Researchers investigated the effect of GSM-like ELF radiation on the alpha band of the human resting EEG. The study used a fully counterbalanced, double-blind, cross-over design with 72 healthy volunteers. A decrease in the alpha frequency band was observed during 20 minutes of ELF exposure in the exposed hemisphere only.

. The spectral power coherence of the EEG under different EMF conditions.

Hountala CD et al. · 2008

Researchers introduced spectral power coherence as a measure of coordination among four EEG frequency bands at a specific brain location. They found that delta rhythm contributes less to this coordination than theta, alpha, and beta rhythms. Gender differences in overall spectral power coherence were observed without radiation, but these differences disappeared during 900 MHz exposure and reversed during 1800 MHz exposure. The measure was calculated from pre-stimulus EEG during an auditory memory task under 900 MHz and 1800 MHz electromagnetic field conditions.

Prenatal and Postnatal Exposure to Cell Phone Use and Behavioral Problems in Children

Divan HA, Kheifets L, Obel C, Olsen J · 2008

Mothers of 13,159 children completed a follow-up questionnaire reporting cell phone use during pregnancy and the child's current cell phone use. Greater odds ratios for behavioral problems were observed for children with possible prenatal or postnatal exposure to cell phone use. After adjustment for potential confounders, the odds ratio for a higher overall behavioral problems score was 1.80 (95% confidence interval = 1.45–2.23) in children with both prenatal and postnatal exposure. The authors noted that these associations may be noncausal and may be due to unmeasured confounding.

Nonthermal effects of radiofrequency-field exposure on calcium dynamics in stem cell-derived neuronal cells: elucidation of calcium pathways.

Rao VS et al. · 2008

The study used neuronal cells differentiated from a mouse embryonic stem cell line and a frequency-tunable applicator to examine calcium dynamics in real time. Control cells showed about five spontaneous calcium spikes per cell in 60 minutes, while exposure to 800 MHz RF radiation at 0.5 W/kg increased spikes to 15.7 per cell. The increase depended on frequency but not on SAR between 0.5 and 5 W/kg, and involved N-type calcium channels and phospholipase C enzymes. Microfilament disruption prevented the calcium spikes.

Mercury release from dental amalgam restorations after magnetic resonance imaging and following mobile phone use

Mortazavi SM et al. · 2008

In the first phase, 30 patients provided saliva samples before and after a 30-minute MRI at 0.23 T. Saliva mercury concentrations increased from 8.6 ± 3.0 to 11.3 ± 5.3 µg L⁻¹ after MRI (p < 0.01). In the second phase, 14 female university students with no prior mobile phone use received amalgam restorations and gave urine samples before and on days 1-4 after. Urinary mercury levels were significantly higher in the mobile-phone users than in controls across the four days (p < 0.05).

Effect of 7, 14 and 21 Hz modulated 450 MHz microwave radiation on human electroencephalographic rhythms.

Hinrikus H, Bachmann M, Lass J, Tomson R, Tuulik V. · 2008

Thirteen healthy volunteers were exposed to 450 MHz microwaves pulse-modulated at frequencies of 7, 14 and 21 Hz to evaluate effects on electroencephalographic (EEG) rhythms. Modulated microwaves caused an average increase in EEG alpha power of 17% and beta power of 7%, while the theta rhythm remained unaffected. Increases in EEG alpha and beta power were statistically significant during the first 30 seconds of exposure at modulation frequencies of 14 and 21 Hz, but no enhancement occurred at 7 Hz. The researchers also found differences in individual sensitivity to exposure, with increases in EEG beta power appearing statistically significant in four subjects.

Psychomotor performance is not influenced by brief repeated exposures to mobile phones.

Curcio G et al. · 2008

The study investigated whether repeated brief exposures to a GSM mobile phone signal had a cumulative effect on psychomotor functions. After each of 3 15-min exposures, both an acoustic simple reaction time task and a sequential finger tapping task were administered to subjects. No cumulative effects were detected, though there was a non-statistical trend toward shorter reaction times.

Effect of head-only sub-chronic and chronic exposure to 900-MHz GSM electromagnetic fields on spatial memory in rats.

Ammari M et al. · 2008

Researchers investigated the effects of sub-chronic and chronic head-only exposure to 900 MHz GSM signals on spatial memory in male rats. Rats were exposed for 45 minutes per day at a SAR of 1.5 W Kg(-1), or 15 minutes per day at a SAR of 6 W Kg(-1), for either 8 or 24 weeks, and then tested in a radial-arm maze. Spatial memory was unaffected in the exposed rats, while scopolamine-treated positive control rats showed a deficit in the spatial memory task.

Extremely low frequency (ELF) magnetic fields enhance chemically induced formation of apurinic/apyrimidinic (AP)sites in A172 cells.

Koyama S, Sakurai T, Nakahara T, Miyakoshi J · 2008

Researchers measured apurinic/apyrimidinic (AP) sites in human glioma A172 cells after exposure to extremely low frequency (ELF) magnetic fields, genotoxic chemicals, or both. ELF magnetic fields alone produced no difference in AP sites compared with sham controls. The results suggest that the number of AP sites induced by MMS or H2O2 is enhanced by exposure to ELF magnetic fields at 5 millitesla (mT).

Extremely low-frequency electromagnetic field exposure during chronic morphine treatment strengthens downregulation of dopamine D2 receptors in rat dorsal hippocampus after morphine withdrawal.

Wang X et al. · 2008

Researchers exposed rats to extremely low-frequency electromagnetic fields (20 Hz, 14 mT) for one hour per day before daily morphine injections for 12 days, then measured dopamine D2 receptor density in the dorsal hippocampus during withdrawal. Morphine withdrawal alone significantly lowered D2 receptor density compared to saline controls, and ELF-EMF exposure during morphine treatment further reduced receptor density on the first and third withdrawal days. In both groups, D2 receptor density tended to recover as the number of withdrawal days increased.

Physiologically patterned weak magnetic fields applied over left frontal lobe increase acceptance of false statements as true.

Ross ML, Koren SA, Persinger MA. · 2008

Researchers tested whether a weak magnetic field pulsed over the left prefrontal brain region at the moment of accepting or refuting a statement could increase the likelihood of later accepting a false statement as true. Fifty men and women were each exposed to one of four magnetic field conditions, or a sham field, over the left prefrontal region above the eyebrow. Groups that received the burst-firing or 25 Hz pulsed fields during the refutation process accepted about twice the number of false statements as true compared to those in the 50 Hz or sham-field conditions. The treatments did not significantly affect the numbers of true statements accepted as false.

Learn More

For a comprehensive exploration of EMF health effects including brain & nervous system, along with practical protection strategies, explore these books by R Blank and Dr. Martin Blank.

FAQs: EMF & Brain & Nervous System

When you review the peer-reviewed literature on electromagnetic field exposure and brain function, the numbers tell a compelling story: 84% of the 2,753 studies examining this relationship have documented measurable effects. This isn't a fringe concern or preliminary finding. This is the dominant scientific picture, and it deserves your attention. The documented effects span multiple systems within your nervous system.
The SYB Research Database includes 1,950 peer-reviewed studies examining the relationship between electromagnetic field exposure and brain & nervous system. These studies have been conducted by researchers worldwide and published in scientific journals. The research spans multiple decades and includes various types of EMF sources including cell phones, WiFi, power lines, and other common sources of electromagnetic radiation.
83% of the 1,950 studies examining brain & nervous system found measurable biological effects from EMF exposure. This means that 1621 studies documented observable changes in biological systems when exposed to electromagnetic fields. The remaining 17% either found no significant effects or had inconclusive results, which is typical in scientific research where study design and exposure parameters vary.