3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.
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Brain & Nervous System

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Key Finding: 78% of 1,644 studies on brain & nervous system found biological effects from EMF exposure.

Of 1,644 studies examining brain & nervous system, 78% found measurable biological effects from EMF exposure.

Lowest Documented Effect

Research found effects on brain & nervous system at exposures as low as:

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in Context0.0000000043Extreme Concern5 mGFCC Limit2,000 mGEffects observed in the No Concern range (Building Biology)FCC limit is 465,116,279,070x higher than this exposure level

Research Overview

  • -When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research.
  • -Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health.
  • -This isn't a handful of outlier studies or preliminary findings - this represents decades of research from laboratories worldwide showing remarkably consistent results.

When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research. Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health. This isn't a handful of outlier studies or preliminary findings - this represents decades of research from laboratories worldwide showing remarkably consistent results.

Henry Lai's comprehensive analysis of peer-reviewed research, 91% of studies examining extremely low frequency fields found biological effects on the nervous system, while 72% of radiofrequency studies showed similar impacts.

The scientific evidence demonstrates that radiofrequency electromagnetic fields from mobile phones and wireless devices produce measurable effects on nervous system function and cellular processes in the brain.

Source: BioInitiative Working Group. BioInitiative Report: A Rationale for Biologically-based Public Exposure Standards for Electromagnetic Radiation. Edited by Cindy Sage and David O. Carpenter, BioInitiative, 2012, updated 2020. www.bioinitiative.org

Research Statistics by EMF Type

EMF TypeStudiesShowing EffectsPercentage
ELF22920891.00%
RF30522272.00%

Source: Dr. Henry Lai research database, BioInitiative Report

Showing 1,644 studies

Brain tumors and salivary gland cancers among cellular telephone users

Auvinen A, Hietanen M, Luukkonen R, Koskela R-S, · 2002

Finnish researchers studied 398 brain tumor patients and 34 salivary gland cancer patients from 1996 to see if cell phone use increased cancer risk. They found no overall link between cell phones and these cancers, but discovered a weak connection between brain tumors called gliomas and older analog cell phones. The researchers noted their study had significant limitations because they couldn't measure actual radiation exposure levels.

Effects of exposure to low level radiofrequency fields on acetylcholine release in hippocampus of freely moving rats.

Testylier G, Tonduli L, Malabiau R, Debouzy JC · 2002

Researchers exposed freely moving rats to radiofrequency radiation at frequencies used by WiFi (2.45 GHz) and cell phones (800 MHz) to study effects on brain chemistry. They found that higher power exposures significantly reduced acetylcholine release in the hippocampus by 40-43%, a brain chemical crucial for memory and learning. The effects persisted for hours after exposure ended, suggesting that even brief RF exposure can disrupt normal brain function.

The effect of low level continuous 2.45 GHz waves on enzymes of developing rat brain.

Paulraj R, Behari J · 2002

Researchers exposed young rats to 2.45 GHz microwave radiation (the same frequency used in WiFi and microwave ovens) for 2 hours daily over 35 days at very low power levels. They found significant changes in brain chemistry, including disrupted calcium levels and altered enzyme activity that controls cell growth and development. The authors concluded these changes could promote tumor development in the developing brain.

Effects of 7 Hz-modulated 450 MHz electromagnetic radiation on human performance in visual memory tasks.

Lass L et al. · 2002

Researchers exposed 100 volunteers to low-level 7 Hz-modulated radio frequency radiation (similar to older cell phone frequencies) for 10-20 minutes and tested their attention and memory skills. The exposed group showed increased variability in error rates on two attention tasks, while surprisingly performing better on one memory task. This suggests that even brief, low-level RF exposure can measurably alter cognitive performance in complex ways.

[Enzymatic activity of some tissues and blood serum from animals and humans exposed to microwaves and hypothesis on the possible role of free radical processes in the nonlinear effects and modification of emotional behavior of animals]

Akoev IG et al. · 2002

Russian researchers exposed rats and humans to very low-power microwave radiation (0.8-10 microW/cm²) and measured changes in key enzymes that control cellular energy and brain chemistry. They found that even these extremely weak exposures triggered complex biochemical changes, including altered enzyme activity and behavioral changes in rats. The researchers propose that microwaves activate free radicals in cells, setting off chain reactions that can damage cellular energy production.

Enzymatic activity of some tissues and blood serum from animals and humans exposed to microwaves and hypothesis on the possible role of free radical processes in the nonlinear effects and modification of emotional behavior of animals

Akoev IG et al. · 2002

Researchers exposed animals and humans to low-level microwaves (0.0008-0.01 microwatts per square centimeter) and measured changes in enzyme activity in blood and tissues. They found that microwave exposure triggered free radical formation and disrupted key enzymes involved in brain chemistry, including those that regulate mood-related neurotransmitters. The study suggests that even very low microwave exposure can create a cascade of cellular damage that affects brain function and emotional behavior.

Effects of extremely low frequency electromagnetic field and its combination with lead on the antioxidant system in mouse.

Liu Y, Weng E, Zhang Y, Hong R. · 2002

Researchers exposed mice to 50 Hz magnetic fields for two weeks and measured cellular damage. Higher magnetic field strengths increased harmful oxidative stress while reducing natural antioxidant defenses in brain and liver tissue, suggesting EMF exposure may compromise the body's ability to protect against cellular damage.

Cancer & TumorsNo Effects Found

The Effects of 860 MHz Radiofrequency Radiation on the Induction or Promotion of Brain Tumors and Other Neoplasms in Rats.

Zook BC, Simmens SJ, · 2001

Researchers exposed rats to 860 MHz radiofrequency radiation for up to 22 months to see if it could cause or accelerate brain tumors. The study found no statistically significant increase in brain tumors or other cancers from the RF exposure, even when combined with a known cancer-causing chemical. This was a large, well-controlled study using 900 rats with extensive tissue analysis.

Whole Body / GeneralNo Effects Found

Effect of immobilization and concurrent exposure to a pulse-modulated microwave field on core body temperature, plasma ACTH and corticosteroid, and brain ornithine decarboxylase, Fos and Jun mRNA.

Stagg RB et al. · 2001

Researchers exposed rats to cell phone radiation at levels up to 5 W/kg (similar to older phones held directly against the head) while measuring stress hormones and brain activity markers. The study found no differences in stress responses between animals exposed to the radiation versus those that were only restrained, suggesting the radiation itself didn't cause additional stress at these exposure levels.

Symptoms & SensitivityNo Effects Found186 citations

Mobile phone use and subjective symptoms. Comparison of symptoms experienced by users of analogue and digital mobile phones.

Sandstrom M, Wilen J, Oftedal G, Hansson Mild K · 2001

Researchers compared symptoms between users of older analog phones (NMT) and newer digital phones (GSM) among nearly 17,000 people in Sweden and Norway. Contrary to initial reports suggesting digital phones caused more symptoms, the study found GSM users actually experienced fewer symptoms like ear warmth and headaches. However, people who talked longer on either type of phone reported more symptoms overall.

Cancer & TumorsNo Effects Found

Cellular Telephones and Cancer-a Nationwide Cohort Study in Denmark.

Johansen C, Boice JD, McLaughlin JK, Olsen JH, · 2001

Danish researchers tracked over 420,000 cellular phone users from 1982 to 1995 and compared their cancer rates to the general population. They found cell phone users actually had lower overall cancer rates than expected, with no increased risk for brain tumors, salivary gland cancers, or leukemia. The study found no connection between phone use duration and cancer risk.

Cancer & TumorsNo Effects Found516 citations

Cellular-telephone use and brain tumors.

Inskip PD et al. · 2001

Researchers examined 782 brain tumor patients and 799 controls to see if cell phone use increases brain tumor risk. They found no increased risk of glioma, meningioma, or acoustic neuroma among people who used cell phones for more than 100 hours or regularly for five or more years. However, the study period (1994-1998) means it couldn't assess risks from long-term heavy use or tumors that take decades to develop.

Miniplate osteosynthesis and cellular phone create disturbance of infraorbital nerve.

Westermark A, Wisten A. · 2001

Researchers investigated a 37-year-old man who experienced nerve pain (dysesthesia) near a metal surgical plate in his face whenever he used his cell phone. When they measured electrical currents on the plate during phone use, they found the phone's electromagnetic field induced measurable currents of up to 141 millivolts on the metal. After surgically removing the plate, the patient's phone-related nerve pain disappeared completely.

Ibuprofen effects on behavioral thermoregulation with microwave radiation in albino rats.

Vitulli WF, Nemeth YM, Conte CT · 2001

Researchers trained rats to press a lever to receive brief microwave radiation for warmth in a cold chamber, then tested how the painkiller ibuprofen affected this heat-seeking behavior. They found that rats given ibuprofen sought microwave heat more frequently and pressed the lever faster, especially during the first two hours of testing. This suggests that ibuprofen disrupts the body's normal temperature regulation when exposed to microwave radiation.

Symptoms experienced by users of digital cellular phones: a pilot study in a French engineering school.

Santini R et al. · 2001

French researchers surveyed 161 engineering students and workers about symptoms they experienced while using digital cell phones operating at 900 MHz and 1800 MHz frequencies. They found that users of the higher frequency phones (1800 MHz) reported significantly more concentration difficulties, while women experienced more sleep disturbances than men. Phone users also reported physical discomfort including ear warmth and pricking sensations that increased with longer daily use.

Changes in the dielectric properties of rat tissue as a function of age at microwave frequencies.

Peyman A, Rezazadeh AA, Gabriel C · 2001

Researchers measured how different rat tissues absorb microwave radiation at various ages, from young to adult rats. They found that younger animals' tissues absorb significantly more radiation than older animals, particularly in brain, skull, and skin tissues. This suggests that children may absorb more EMF radiation from cell phones and other wireless devices than adults do.

Effect on human attention of exposure to the electromagnetic field emitted by mobile phones.

LeeTMC, HoSMY, Tsang LYH, Yang SYC, LiLSW, ChanCCH · 2001

Researchers tested attention abilities in 72 teenagers, comparing 37 mobile phone users to 35 non-users. Mobile phone users performed better on one of three attention tests, suggesting that electromagnetic field exposure from cell phones might actually improve certain cognitive functions. This finding aligns with other research showing EMF exposure can enhance some types of brain processing.

Investigation of brain potentials in sleeping humans exposed to the electromagnetic field of mobile phones.

Lebedeva NN et al. · 2001

Researchers monitored brain activity in sleeping people exposed to cell phone radiation for 8 hours, comparing it to nights without exposure. They found that cell phone electromagnetic fields altered brain wave patterns during sleep, specifically increasing alpha waves (brain waves associated with relaxed wakefulness) and changing how sleep stages progressed. This suggests that even during sleep, when phones aren't actively being used nearby, the radiation can still influence normal brain function.

Microwave sickness: a reappraisal.

Hocking B · 2001

Researchers examined 'microwave sickness' (MWS), a disputed condition affecting workers exposed to radiofrequency radiation, characterized by fatigue, headaches, and nervous system problems. The study concluded that MWS is a legitimate medical condition that should be recognized as a potential occupational health risk for RF radiation workers. This challenges decades of Western skepticism about reports from Eastern European researchers.

Cancer & Tumors163 citations

Ionizing radiation, cellular telephones and the risk of brain tumours.

Hardell L, Hansson Mild K, Pahlson A, Hallquist A · 2001

Swedish researchers studied 233 brain tumor patients and 425 healthy controls to examine various risk factors for brain tumors, including cell phone use. They found that people who used cell phones on the same side of their head where tumors developed had a 2.42 times higher risk of developing brain tumors in the areas closest to where phones emit radiation. The study also identified increased risks from occupational radiation exposure and certain chemical industry jobs.

[Effect of vitamin E on morphological variation of retinal ganglion cells after microwave radiation].

Yang R, Chen J, Deng Z, Liu X, · 2001

Researchers exposed pig retinal ganglion cells (nerve cells in the eye that transmit visual information to the brain) to microwave radiation at 2450 MHz for one hour and observed significant cellular damage including cell death, swollen cellular structures, and disappeared nerve fibers. When vitamin E was added to the cell cultures, it provided partial protection against this microwave-induced damage, though some cellular changes still occurred.

Effects of radiofrequency exposure on the GABAergic system in the rat cerebellum: clues from semi-quantitative immunohistochemistry

Mausset A, de Seze R, Montpeyroux F, Privat A · 2001

French researchers exposed rats to 900 MHz radiofrequency radiation (the same frequency used by many cell phones) and measured changes in GABA, a crucial brain chemical that helps regulate nerve activity. They found that RF exposure reduced GABA levels in the cerebellum, the brain region responsible for movement and coordination. This suggests that cell phone radiation may disrupt normal brain chemistry at the cellular level.

Learn More

For a comprehensive exploration of EMF health effects including brain & nervous system, along with practical protection strategies, explore these books by R Blank and Dr. Martin Blank.

FAQs: EMF & Brain & Nervous System

When 81.3% of studies examining EMF effects on the brain and nervous system report biological changes, we're looking at one of the most consistent patterns in EMF research. Out of 1,344 peer-reviewed studies, 1,092 have documented measurable impacts on neural function, brain activity, and nervous system health.
The BioInitiative Report database includes 1,644 peer-reviewed studies examining the relationship between electromagnetic field exposure and brain & nervous system. These studies have been conducted by researchers worldwide and published in scientific journals. The research spans multiple decades and includes various types of EMF sources including cell phones, WiFi, power lines, and other common sources of electromagnetic radiation.
78% of the 1,644 studies examining brain & nervous system found measurable biological effects from EMF exposure. This means that 1284 studies documented observable changes in biological systems when exposed to electromagnetic fields. The remaining 22% either found no significant effects or had inconclusive results, which is typical in scientific research where study design and exposure parameters vary.