Hung CS, Anderson C, Horne JA, McEvoy P. · 2007
Researchers exposed 10 healthy young adults to a GSM mobile phone in 'talk mode' for 30 minutes during the day, then measured how long it took them to fall asleep afterward. They found that exposure to the phone's talk-mode signal significantly delayed the onset of sleep compared to when the phone was off or in other modes. The study suggests that the specific radio frequency patterns used during phone calls may interfere with the brain's natural transition to sleep.
Unknown authors · 2007
Researchers analyzed 60 children with acute leukemia and 59 matched controls in a city in North-Western Iran. They assessed exposure to very high voltage power lines of 123, 230, and 400 kilovolts. Fourteen cases (23.5%) lived within 500 meters of such lines compared with two controls (3.3%), giving an odds ratio of 8.67. Fifteen cases (25%) experienced magnetic fields above 0.45 microtesla versus five controls (8.5%), with an odds ratio of 3.60.
Hamann W, Abou-Sherif S, Thompson S, Hall S. · 2006
Researchers applied pulsed radiofrequency (20 ms of 500-kHz RF pulses at 2 Hz, max 42°C) to the sciatic nerve or L4 anterior primary ramus in adult rats. Controls included sham-operated and L4 axotomised rats, and tissues were examined 14 days later. Axotomy upregulated ATF3 in L4 DRG neurons regardless of size. PRF applied near the DRG significantly and selectively increased ATF3 in small and medium neurons, while PRF applied to the sciatic nerve in mid-thigh caused no obvious changes.
Unknown authors · 2006
Researchers conducted a population-based case-control study covering areas with 54% of Japanese children, analyzing 312 cases of acute lymphoblastic or myelocytic leukemia and 603 matched controls. Weekly mean magnetic field levels were measured in the child's bedroom, with measurements for each case-control set taken close in time to control for seasonal variation. The odds ratio for all leukemia combined was 2.6 (95% CI 0.76–8.6) and for acute lymphoblastic leukemia alone was 4.7 (95% CI 1.15–19.0) for bedroom fields of 0.4 μT or higher versus below 0.1 μT.
Frahm J, Lantow M, Lupke M, Weiss DG, Simkó M · 2006
Researchers investigated whether extremely low frequency electromagnetic fields affect cellular functions and immunologic parameters of mouse macrophages. Magnetic field exposure led to a 1.6-fold increased uptake of latex beads in exposed cells compared to controls after 45 minutes. IL-1β formation increased significantly after 4 hours and reached a maximum 12.3-fold increase after 24 hours compared to controls. All tested flux densities significantly stimulated free radical formation, and no significant differences in micronucleus formation were found in exposed cells.
Simkó M et al. · 2006
The study investigated Hsp70 expression and free radical release in human Mono Mac 6 cells exposed to ultrafine particles and radiofrequency electromagnetic fields. Ultrafine particle exposure increased free radical release by 40-45% above negative control, an effect stronger than heat treatment. Radiofrequency electromagnetic field exposure alone did not change free radical levels. Combined exposure to RF and ultrafine particles did not enhance the particle effect on free radicals. Heat treatment increased Hsp70 expression in a time-dependent manner, while ultrafine particles, RF fields, or their combination had no effect on Hsp70.
Unknown authors · 2006
Researchers studied the effect of 50 Hz electromagnetic field on the thyroid gland using light and transmission electron microscopes. Two-month-old male rats were exposed to an EMF of 100-300 μT and 54-160 V m-1 for 4 h a day, 5 days a week for 1 month. The EMF group showed a predominance of microfollicles with less colloid content and dilated blood capillaries. Stereological counting revealed a statistically significant increase in the volume density of follicular epithelium, interfollicular tissue, blood capillaries, and the thyroid activation index, while the volume density of colloid significantly decreased.
Unknown authors · 2006
The study used a crossover design with healthy premenopausal women exposed to a 60-Hz magnetic field of 5 to 10 mG greater than ambient levels for 5 consecutive nights during the early to midluteal phase of the menstrual cycle. Magnetic field exposure was associated with decreased 6-sulfatoxymelatonin levels, but no changes in reproductive hormone levels were observed. Participants using prescription medications and anovulatory participants had more pronounced decreases in 6-sulfatoxymelatonin levels with magnetic field exposure.
Unknown authors · 2006
Researchers exposed female mice to 50 Hz, 1.2 mT electromagnetic fields for 8 hours per day throughout pregnancy. Exposed dams gained weight more slowly (29.0% vs 47.8%) and had a lower producing rate (60% of controls), with miscarriages, fetal loss, and malformed fetuses observed. The average number of offspring per mouse decreased (11 ± 1.6 vs 7 ± 2.0), and prenatally exposed offspring showed slower weight gain in the first two weeks and delayed eye opening and tooth eruption.
Unknown authors · 2006
Researchers investigated effects of electromagnetic fields on DNA damage in preimplantation mouse embryos using gammaH2AX foci formation as an indicator. EMFs decreased the cleavage rate of preimplantation mouse embryos. The decreasing effect was related to DNA damage shown by gammaH2AX foci formation. Noise magnetic fields or wortmannin inhibited the EMF-induced gammaH2AX foci formation. EMFs could activate the DNA damage-repair mechanism by recruiting Rad50 to damaged DNA sites.
Unknown authors · 2006
Researchers used the micronucleus test with CREST antibody staining to assess clastogenic and aneugenic effects of a 50 Hz, 650 muT magnetic field. Newborn mice were exposed during the entire 21-day intra-uterine period, and adult mice were exposed for the same duration. Newborn mice showed a significant increase in micronuclei frequencies, with most induced micronuclei being CREST-negative chromosome fragments. ELF exposure caused a two-fold increase in CREST-negative micronuclei and a four-fold increase in CREST-positive micronuclei in newborn mice. No significant effect was observed in exposed adult mice.
Unknown authors · 2006
Unknown authors · 2006
The hypothesis predicts optimal ameliorating effects on experimental allergic encephalomyelitis at derived intensities of about 35 and 70 nT and a frequency of 7 Hz. These predictions were congruent with prior rat experiments using magnetic field strengths of about 1-5000 nT at 0.5, 7, 40, or 60 Hz. The model proposes that weaker fields in the nanoTesla to picoTesla range would optimally affect micromolar melatonin concentrations and that mitochondrial proton gradients may be critical. The model offers an alternative explanation to variations of Faraday's Law and the Boltzmann constant that have been used to dismiss biological effects from weak magnetic fields.
Unknown authors · 2006
This theoretical study by Dr. Michael Persinger proposes that extremely weak magnetic fields in the nanoTesla range (35-70 nT at 7 Hz frequency) could affect melatonin molecules and potentially treat conditions like multiple sclerosis. The hypothesis suggests these fields work through a resonance mechanism that depends on melatonin concentration levels in specific body tissues.
Unknown authors · 2006
This theoretical study by researcher Michael Persinger proposes a mechanism for how extremely weak magnetic fields (in the nanoTesla range) could affect melatonin levels and potentially treat neurological conditions like multiple sclerosis. The hypothesis suggests that 7 Hz magnetic fields at specific intensities (35-70 nanoTesla) could resonate with melatonin molecules to produce therapeutic effects. This challenges conventional thinking that such weak fields are too small to have biological impact.
Espinosa JM, Liberti M, Lagroye I, Veyret B. · 2006
Researchers studied the binding properties of the serotonin 5-HT1B receptor in rat brain membranes under exposure to AC and DC magnetic fields. One-hour exposures at 1.1 mT at 50 Hz caused statistically significant increases in both the K(D) and B(max) binding parameters, from 1.74 to 4.51 nM and from 1428 to 2137 CPM, respectively. DC fields had a lesser effect compared to AC fields at low values of K(Dsham), but decreased the affinity at higher values of K(Dsham). The researchers described these findings as one of the few documented pieces of evidence for cell-free effects of DC and extremely low frequency AC magnetic fields in the mT range.
Unknown authors · 2006
Initial reports indicated that exposure of chicken eggs during embryonic development to power-line electric fields of 50 and 60 Hz at 10 V/m in air could cause the brain tissues of the hatched chickens to respond differently in a particular test. More recently, an anecdotal report of human sensitivity to EMF has appeared that shows a health-related influence of prior exposure history to particular power-line frequencies in chemically sensitized individuals. These reports open the question of whether the ambient electromagnetic environment can leave an imprint on developing organisms and if such imprint changes have the potential for health consequences.
Unknown authors · 2006
This 2006 review examined whether EMF exposure during embryonic development can create lasting physiological changes. Studies found that chicken embryos exposed to common 50-60 Hz power line frequencies (at levels found in human environments) showed altered brain responses after hatching. The research raises concerns about whether EMF exposure during critical developmental periods leaves permanent biological imprints.
Unknown authors · 2006
Researchers investigated the effects of pulsed electric fields at 50 Hz on DNA of human lymphocytes using the comet assay. A significant amount of DNA damage was observed after exposure compared to controls. After 2 hours incubation at 37°C, a proportion of the damage was repaired. Hydrogen peroxide and gamma-irradiation increased the damage to lymphocytes exposed to pulsed electric fields according to the dose used, and the amount of repair was proportional to the damage.
Unknown authors · 2006
Two experiments were carried out to assess the effects of electric and magnetic fields on blood thyroxine in dairy cattle. In experiment 2, 16 nonlactating, nonpregnant, multiparous Holsteins were exposed to the same EMF with periods corresponding to one estrous cycle and blood samples were collected every other day, and the effect of period (P = .0009) and the treatment by days interaction (P = .0003) were statistically significant.
Wang LL, Chen GD, Lu DQ, Chiang H, Xu ZP. · 2006
Researchers intermittently exposed MCF-7 cells to GSM 1800 MHz RF EMF modulated by 217 Hz for 24 hours at SARs of 2.0 W/kg or 3.5 W/kg. A small number of differentially expressed genes were found after exposure. Reproducible analysis yielded no genes at 2.0 W/kg and five up-regulated genes at 3.5 W/kg. The five genes identified at 3.5 W/kg could not be confirmed by RT-PCR. The authors concluded that the study did not provide clear evidence of distinct gene expression changes under the experimental conditions.
Aksen F, Akdag MZ, Ketani A, Yokus B, Kaya A, Dasdag S. · 2006
Jelenković A et al. · 2006
Researchers exposed adult male Wistar rats to a 50 Hz, 0.5 mT extremely low-frequency magnetic field for 7 days, while control rats were sham-exposed. Superoxide dismutase activities and production of superoxide radicals, lipid peroxidation, and nitric oxide were examined in the frontal cortex, striatum, basal forebrain, hippocampus, brainstem, and cerebellum. Superoxide radicals were significantly increased in all regions examined, and lipid peroxidation was significantly increased in the basal forebrain and frontal cortex. The researchers indicated that the 7-day exposure can be harmful to the brain, especially to the basal forebrain and frontal cortex due to development of lipid peroxidation.
Reale M et al. · 2006
Researchers investigated whether overnight exposure to a 1 mT, 50-Hz sinusoidal electromagnetic field affects the expression of iNOS and MCP-1 in human monocytes. EMF exposure affected iNOS and MCP-1 expression in cultured human mononuclear cells at both the mRNA level and the protein level. iNOS was down-regulated while MCP-1 was up-regulated.
Bediz CS, Baltaci AK, Mogulkoc R, Oztekin E. · 2006
Twenty-four male Sprague-Dawley rats were randomly allocated to three groups: control, EMF-exposed (50 Hz, 5 minutes every other day for 6 months), and EMF-exposed with zinc sulfate (3 mg/kg/day intraperitoneally). Researchers measured plasma zinc and TBARS, and GSH in erythrocytes; TBARS and GSH were also determined in brain tissues. TBARS levels in plasma and brain were higher in EMF-exposed rats than controls, and lower in zinc-supplemented rats than EMF-exposed rats. GSH levels decreased in brain and erythrocytes of EMF-exposed rats and were highest in zinc-supplemented rats. Plasma zinc was lower in EMF-exposed rats than controls and highest in zinc-supplemented rats.
