Keleş AI et al. · 2018
Histopathological examination revealed impairments of pyramidal and granular cell structures in the hippocampus of exposed rats. No significant differences were found in learning, memory, or locomotor behavior among the groups.
Hancı H, Kerimoğlu G, Mercantepe T, Odacı E · 2018
Researchers exposed young rats to 900 MHz electromagnetic fields (similar to early cell phone frequencies) for one hour daily throughout adolescence, then examined their reproductive organs at maturity. The study found morphological changes and oxidative stress markers in the testicular tissue of exposed animals compared to unexposed controls.
Unknown authors · 2018
Twelve-week old male mice were exposed to 2.45 GHz microwave radiation at 0.0248 mW/cm2 power density and 0.0146 W/kg SAR for two hours daily over 15, 30, and 60 days. Researchers evaluated testicular histology, serum testosterone, ROS, NO, MDA, antioxidant enzymes, and apoptotic protein expression. Exposure induced testicular redox imbalance that enhanced apoptosis via a p53 dependent Bax-caspase-3 pathway with severity increasing with exposure duration.
Unknown authors · 2018
Researchers exposed mice to 835 MHz radiofrequency radiation at 4.0 W/kg for 12 weeks and found it triggered autophagy (cellular cleanup processes) specifically in the hippocampus brain region but not in the brain stem. This suggests RF-EMF affects different brain areas differently, with the memory-critical hippocampus showing cellular stress responses to phone-like radiation levels.
Unknown authors · 2018
Researchers exposed male mice to 2.45 GHz microwave radiation (the same frequency as WiFi and microwave ovens) for 2 hours daily over 15-60 days. The radiation triggered a cascade of cellular damage in the testes, leading to sperm cell death through a specific molecular pathway involving oxidative stress and programmed cell death. Longer exposure periods caused progressively more severe damage to reproductive tissue.
Unknown authors · 2018
Unknown authors · 2018
López-Furelos A et al. · 2018
Researchers exposed RAW 264.7 macrophage cells to single or combined radiofrequency signals at 900 and 2450 MHz for 4, 24, 48, or 72 hours in a GTEM chamber. They measured cell viability, nitric oxide production, HSP70 and TNF-α expression, and phagocytic activity. Phagocytic activity declined with longer exposure, while combined exposure raised HSP70 at 48 hours and significantly increased nitric oxide and TNF-α at 72 hours.
Unknown authors · 2018
Mice were exposed to 2.45 GHz microwave radiation at a power density of 0.25 mW/cm2 and SAR of 0.09 W/kg for 2 hours per day over 30 days. Exposure significantly increased catalase, malondialdehyde, and reactive oxygen species while decreasing glutathione peroxidase, testosterone, and superoxide dismutase levels. Flow cytometry revealed micronuclei formation in the blood of exposed mice, and histopathological changes were observed in seminiferous tubules.
Unknown authors · 2018
The study exposed primary cultured astrocytes, microglia, and cortical neurons to RF-EMF at a SAR of 4.0 W/kg. DNA damage was assessed using γH2AX foci formation, cytokine secretion by ELISA, microglial phagocytosis by phagocytosis assay, and neuronal development by immunofluorescent staining for specific proteins. RF-EMF exposure did not significantly induce γH2AX foci formation in the three neurogenic cell types. Cytokine secretion in astrocytes and microglia and dendritic or synaptic morphology in cortical neurons were not significantly affected. However, microglial phagocytic activity was significantly reduced and cortical neuron axon branch length and number were significantly inhibited.
Unknown authors · 2018
Researchers exposed male mice to 2.45 GHz microwave radiation (the same frequency as WiFi and microwave ovens) for 2 hours daily over 30 days. The exposed mice showed significant damage to their reproductive systems, including reduced testosterone levels, increased oxidative stress in the testes, and structural damage to sperm-producing tissue. The study demonstrates that everyday wireless frequencies can harm male fertility through cellular damage.
Kamali K, Taravati A, Sayyadi S, Gharib FZ, Maftoon H. · 2018
Researchers exposed male Wister rats to 2.45 GHz Wi-Fi radiation continuously for 10 weeks. Total antioxidant capacity of plasma and activities of CAT, GSH-Px, and SOD decreased significantly in exposed rats. GST activity increased significantly in the exposed group. GSH and TBARS levels did not change significantly after exposure.
Qin F et al. · 2018
Researchers exposed male mice to 1800 MHz radiofrequency fields at 40 μW/cm2 and 0.0553 W/Kg SAR for 2 hours per day over 32 days. The exposure significantly reduced testosterone levels and altered the expression of steroidogenic genes Star, P450scc, P450c17, and 3β-Hsd in testicular tissue. RF exposure also significantly reduced the regulatory protein CaMKI/RORα, and similar effects were observed in cultured primary Leydig cells exposed in vitro. The CaMK inhibitor KN-93 blocked all these observations, and ionomycin reversed the RF-induced down-regulation of intracellular calcium and CaMKI/RORα expression.
Yakymenko I et al. · 2018
Researchers used developing quail embryos to assess the oxidative and mutagenic effects of GSM 1800 MHz microwave radiation from a commercial smartphone. The embryos were exposed in ovo to 0.32 µW/cm2, discontinuously, for 5 days before and 14 days through the incubation period. Exposure resulted in a 2-fold increase in superoxide generation rate, an 85% increase in nitrogen oxide generation rate, and up to twice increased levels of 8-oxo-dG in cells of 1-day old chicks from the exposed embryos. The exposure also resulted in a significant, almost twice, increase of embryo mortality.
Unknown authors · 2018
Male albino Wistar rats were exposed to 900 MHz radiation for 1 hour per day at a power density of 146.60 µW/cm2 from a mobile phone for 28 days. MDA concentration was increased but TA levels and GST activity were not different in the exposed group compared to controls. Sperm motility was slightly reduced and percentage of abnormal sperm was significantly elevated in the exposed group. Loss of germ cells, particularly spermatocytes and spermatids, was found in the testes of exposed rats, and testes caspase-3 activity was slightly elevated.
Yakymenko I et al. · 2018
Researchers exposed quail embryos to low-level GSM 1800 MHz radiation from a commercial smartphone for 19 days during development. The exposure caused significant cellular damage, including doubled rates of harmful molecule production, DNA damage, and nearly doubled embryo death rates. This demonstrates that even weak smartphone radiation can harm developing biological systems.
Yakymenko I et al. · 2018
Ukrainian researchers exposed quail embryos to low-power smartphone radiation (GSM 1800 MHz) during development and found dramatic increases in cellular damage. The radiation doubled superoxide production, increased DNA damage by up to 100%, and nearly doubled embryo death rates. This demonstrates that even very low-intensity cell phone radiation can cause significant biological harm during critical developmental periods.
Unknown authors · 2018
Researchers exposed adolescent male rats to 900 MHz cell phone radiation for one hour daily over 28 days and found significant reproductive damage. The radiation increased oxidative stress in blood, reduced sperm motility, increased abnormal sperm by a significant margin, and caused loss of sperm-producing cells in the testes. This study demonstrates that cell phone frequency radiation can harm male fertility even at relatively low exposure levels.
Qureshi MRA, Alfadhl Y, Chen X, Peyman A, Maslanyj M, Mann S · 2018
Comelekoglu U et al. · 2018
Researchers divided rats into four groups: control, paricalcitol only, RF exposure only, and RF plus paricalcitol. Rats in the RF groups were exposed to 1,800 MHz RF radiation for 1 hour per day for 4 weeks. RF exposure caused significant reduction in nerve signal amplitude, prolonged latency, increased malondialdehyde levels, increased catalase activity, and degeneration of myelinated nerve fibers. Paricalcitol administration partially ameliorated these neuropathic changes.
Unknown authors · 2018
Researchers exposed female rats to a continuous 900-MHz electromagnetic field for one hour daily from postnatal day 35 to 59. Control, sham, and EMF groups were established, with sham rats receiving a pseudo-megahertz effect. All animals were euthanized on postnatal day 60 and kidney tissues were analyzed for histopathology and oxidative stress markers. Histopathological analysis showed no pathology in control or sham groups, but the EMF group exhibited hemorrhage in glomeruli, vacuolization and irregularity in tubular epithelium, glomerular degeneration and edema, Bowman capsule degeneration, medullary hemorrhage, disturbed nuclei, and cortical tubular edema. Total oxidant status and oxidative stress index values were significantly lower in both EMF and sham groups compared with controls.
Masoumi A, Karbalaei N, Mortazavi SMJ, Shabani M. · 2018
The Wi-Fi exposure used a frequency of 2.45 GHz. The Wi-Fi exposed group had significantly lower weight gain than controls and developed hyperglycemia. Plasma insulin levels and glucose-stimulated insulin secretion from pancreatic islets were significantly reduced, while pancreatic lipid peroxidation increased and GSH, SOD, and GPx activities decreased.
Unknown authors · 2018
Twenty-four 34-day-old female Sprague-Dawley rats were divided into control, sham, and EMF exposure groups. The EMF group received 900-MHz electromagnetic field exposure for 1 hour daily from postnatal days 35 to 59. Ovarian tissue in the EMF group showed thinning of granulosa and theca layers, shrunken granulosa cells, reduced mitotic activity, and leukocyte infiltration. Secondary follicle counts were significantly lower in the EMF group than in the control or sham groups. Biochemical analysis found increased oxidative stress markers and antioxidant enzymes in both EMF and sham groups compared to controls, with the EMF group showing the highest total oxidant status and oxidative stress index.
Unknown authors · 2018
Researchers exposed adolescent female rats to 900 MHz electromagnetic fields (the same frequency used by older cell phones) for one hour daily during their reproductive development. The EMF exposure caused significant damage to ovarian tissue, including reduced follicle numbers, cellular shrinkage, and increased oxidative stress markers. This suggests that EMF exposure during critical developmental periods may harm female reproductive health.
Unknown authors · 2018
Researchers exposed female rats to 900 MHz electromagnetic fields (cell phone frequency) for one hour daily during adolescence. The EMF-exposed rats showed significant damage to their ovaries, including fewer secondary follicles, cellular shrinkage, and increased oxidative stress markers. This suggests that cell phone radiation during adolescence may harm female reproductive development.