Ono T et al. · 2004
A possible mutagenic effect of 2.45 GHz radiofrequency exposure was examined using lacZ-transgenic MutaTM mice. Offspring were exposed in utero for 16 hours a day from embryonic day 0 to 15 and examined at 10 weeks of age. Mutation frequencies at the lacZ gene in spleen, liver, brain, and testis were similar to those in non-exposed mice. Sequencing of mutant DNAs showed no appreciable difference in mutation quality between exposed and non-exposed samples.
Unknown authors · 2004
Researchers exposed cerebral cortical neurons from postnatal rats to low-intensity 900MHz continuous microwave electromagnetic fields at 9mW/cm2 with a SAR of 3.22mW/g for 2 hours per day over 4 or 5 consecutive days and also for 12 hours at a time. They measured cytochrome oxidase activity as a marker of energy metabolism. Compared to sham-exposed neurons, cytochrome oxidase activity decreased significantly in neurons exposed for 2 hours per day and in those exposed for 12 hours (P < 0.001).
Unknown authors · 2004
Chinese researchers exposed developing rat brain neurons to 900 MHz microwave radiation (the frequency used by many cell phones) and found significant decreases in cellular energy production. The study showed that even low-intensity exposure damaged the neurons' ability to generate energy, with effects occurring after just 2 hours of daily exposure.
Unknown authors · 2004
Chinese researchers exposed developing rat brain neurons to 900 MHz microwave radiation (the same frequency used by many cell phones) and found significant decreases in cytochrome oxidase activity, a key enzyme for cellular energy production. The effects occurred at power levels similar to those from mobile devices and persisted even with brief daily exposures over several days.
Haarala C et al. · 2003
Sixty-four subjects (32 men, 32 women) in two independent laboratories performed nine cognitive tasks twice, once with the EMF on and once with it off. Reaction times and accuracy were recorded, and the order of exposure and tasks was counterbalanced across subjects and gender. There were no statistically significant differences in performance between genders or laboratories. The previous results were not replicated, and the researchers concluded that EMF had no effect on reaction times or accuracy.
Weisbrot D, Lin H, Ye L, Blank M, Goodman R. · 2003
Researchers exposed fruit flies to a discontinuous RF signal from a GSM multiband phone at 900/1,900 MHz with SAR approximately 1.4 W/kg for 10 days from egg laying through pupation. The non-thermal radiation increased offspring numbers, elevated hsp70 levels, increased SRE DNA-binding, and induced ELK-1 phosphorylation.
Dubreuil D, Jay T, Edeline JM. · 2003
Researchers exposed rats head-only to 900 MHz GSM electromagnetic fields at 1 and 3.5 W/kg for 45 minutes and compared performance with sham and control rats. In the first experiment, a slightly improved performance was found at 3.5 W/kg, but this was not seen in the delay task. In the third experiment, exploratory activity showed some effects but recognition memory was unaffected. Overall, the experiments provided no evidence that spatial or non-spatial memory is affected by this exposure.
Zeni et al. · 2003
Zeni, O., Schiavoni, A. · 2003
Researchers exposed human peripheral blood lymphocytes from 20 healthy donors to 900 MHz electromagnetic fields under various conditions. Exposures included continuous-wave and GSM-modulated signals at specific absorption rates of 1.6 W/kg and 0.2 W/kg with different intermittent patterns. No statistically significant differences were found in micronucleus frequency or cell cycle kinetics across any exposure condition.
McNamee, J. · 2003
Anderson V. · 2003
The study aimed to examine the scale and significance of differences in peak specific energy absorption rate (SAR) in the brains of children and adults exposed to radiofrequency emissions from mobile phones. Model analyses using a three-layered spherical head exposed to a dipole at 900 MHz showed that peak brain 10 g averaged SAR in 4, 8, 12, and 16 year olds increased by factors of 1.31, 1.23, 1.15, and 1.07 compared to an average adult. The researchers concluded that the relatively small scale of these increases does not warrant special precautionary measures for child mobile phone users.
Gatta L et al. · 2003
Researchers exposed C57BL/6 mice to 900 MHz GSM-modulated radiation at SAR 1 or 2 W/kg for 2 hours per day over 1, 2, or 4 weeks. The number of spleen cells, percentages of B and T cells, and CD4/CD8 distribution were not altered by exposure. After 1 week of exposure, IFN-gamma production increased, but this effect was not seen after 2 or 4 weeks.
Irmak MK, Oztas E, Yagmurca M, Fadillioglu E, Bakir B. · 2003
Researchers investigated the influence of electromagnetic radiation from a 900 MHz cellular telephone on Merkel cells in rats. One group of rats was exposed to a cellular telephone in speech position for 30 minutes while another group was sham-exposed under the same conditions. Exposure led to significantly higher exocytotic activity in Merkel cells compared with the sham exposure group.
Dabrowski MP et al. · 2003
Researchers exposed cultured human blood mononuclear cells isolated from 16 healthy donors to 1300 MHz pulse-modulated microwaves at a power density of 10 W/m2 and a SAR of 0.18 W/kg. Lymphocyte proliferative responses and IL-2 receptor saturation did not change, though lymphocyte production of IL-10 increased (P < .001). Monocyte production of IL-1β increased significantly (P < .01), the concentration of its antagonist IL-1ra dropped by half (P < .01), and TNF-α remained unchanged. The researchers concluded that pulse-modulated microwaves represent the potential of immunotropic influence, stimulating preferentially the immunogenic and proinflammatory activity of monocytes at relatively low levels of exposure.
Dabrowski MP et al. · 2003
Researchers exposed immune cells from 16 healthy people to low-level cell phone radiation (1300 MHz) and found significant changes in immune system function. The radiation increased production of inflammatory molecules (IL-1β and IL-10) while decreasing protective factors, essentially pushing the immune system toward a more inflammatory state. These changes occurred at radiation levels similar to what you might experience from cell phone use.
Yamaguchi H et al. · 2003
Sprague-Dawley rats were exposed to pulsed 1439 MHz TDMA fields at a brain SAR of 7.5 W/kg for 1 hour daily over 4 days or 4 weeks. Other rats were exposed at a brain SAR of 25 W/kg for 45 minutes daily for 4 days. Rats exposed at 25 W/kg for 4 days showed statistically significant decreases in correct choices in a T-maze reversal task, while rats exposed at 7.5 W/kg for 4 days or 4 weeks showed no performance impairments. Intraperitoneal temperature increased only at the 25 W/kg exposure level. The authors concluded that TDMA fields at levels about four times higher than cell phone emissions do not affect learning and memory when no thermal effects occur.
Vijayalaxmi, Sasser LB, Morris JE, Wilson BW, Anderson LE. · 2003
Timed-pregnant Fischer 344 rats and their nursing offspring were exposed to a far-field 1.6 GHz Iridium signal for 2 h/day, 7 days/week. The offspring then received chronic head-only near-field exposure to a 1.6 GHz signal for 2 h/day, 5 days/week over 2 years. Near-field exposures were conducted at brain SARs of 0.16 or 1.6 W/kg. The incidence of micronuclei in bone marrow did not differ significantly between exposed, sham-exposed, and cage control rats.
Monfrecola G, Moffa G, Procaccini EM. · 2003
The study assessed the effects of non-ionizing electromagnetic radiation emitted by CFs on cutaneous blood flow in 30 healthy volunteers aged 18 to 53 years. Cutaneous blood flow was measured on the ear skin with a laser Doppler He-Ne flowmeter under controlled temperature and humidity. Microflow was recorded across phases T0 through T6, including no CF contact, CF off touching the ear, CF on, CF on and receiving, then back through CF on, CF off, and no contact. During phases T1 to T5 microflow increased by 61.38% to 157.67% relative to baseline, and all these phases showed statistically significant elevations compared with baseline.
Aweda MA, Gbenebitse S, Meidinyo RO · 2003
Researchers studied the effects of 2.45 GHz microwave exposure on the lipid peroxidation status of 120 Wistar rats at a power density of 6 mWcm(-2). Lipid peroxidation status in the rats was monitored for 8 weeks after irradiation using the thiobarbituric acid method. Microwave exposure raised the lipid peroxidation status from a mean control value of 4.18 x 10(-6)g 1(-1) to a maximum of 6.50 x 10(-6) g 1(-1) within the first 24 hours, after which it gradually returned toward the control value. The results demonstrated that microwave exposures cause a significant increase in lipid peroxidation status and that ascorbic acid and alpha-tocopherol had protective effects.
Aweda MA, Gbenebitse S, Meidinyo RO. · 2003
Researchers exposed rats to 2.45 GHz microwave radiation (WiFi frequency) and found it increased cellular damage by 56% within 24 hours. Vitamins C and E provided significant protection when given beforehand, suggesting antioxidants may help reduce microwave-induced oxidative stress in living tissue.
Bakos J, Kubinyi G, Sinay H, Thuroczy G. · 2003
Researchers studied the effect of 900 and 1800 MHz GSM-like radiofrequency radiation on urinary 6-sulfatoxymelatonin excretion in adult male Wistar rats. Seventy-two rats were used in six independent experiments with exposures in a GTEM cell at power densities of 100 μW/cm² at 900 MHz and 20 μW/cm² at 1800 MHz. Animals were exposed for 2 hours daily between 8:00 AM and noon for 14 days with 218 Hz GSM modulation. No statistically significant changes in 6-sulfatoxymelatonin excretion were found at either frequency.
Aweda MA, Gbenebitse S, Meidinyo RO · 2003
Researchers exposed 120 rats to 2.45 GHz microwave radiation (the same frequency as microwave ovens) and found it significantly increased harmful oxidative stress in their bodies. However, giving the rats antioxidants like vitamin C and vitamin E before exposure provided substantial protection against this cellular damage.
Kainz W, Alesch F, Chan DD. · 2003
Researchers tested 10 GSM phones at 900 MHz and 10 at 1800 MHz on the ITREL-III deep brain stimulator in a phantom model. At maximum phone power of 2 W at 900 MHz and 1 W at 1800 MHz, no influence on the stimulator was observed, and pulse shape and single pulses remained unchanged. However, tests with continuous-wave signals showed inhibition occurs at power levels below GSM phone emissions, with the device more sensitive at 1800 MHz than at 900 MHz and a very low interference threshold around 1500 MHz. The authors concluded no direct risk for patients using the tested phones but recommended precautions similar to cardiac pacemaker guidelines.
Anane R et al. · 2003
Researchers investigated the effects of acute GSM-900 microwave exposure on the clinical parameters of the acute EAE rat model in two independent experiments with habituated and nonhabituated rats. Female Lewis rats were divided into cage control, sham exposed, and two groups exposed at 1.5 or 6.0 W/kg local SAR averaged over the brain using a loop antenna over their heads. EAE was induced with a mixture of myelin basic protein and Mycobacterium tuberculosis. The 21-day exposure at 2 hours per day had no effect on the onset, duration, or termination of the EAE crisis.
Zhang MB, Jin LF, He JL, Hu J, Zheng W. · 2003
The study aimed to investigate the combined DNA-damaging effects of low-intensity 2,450 MHz microwave radiation with three chemical mutagens on human lymphocyte DNA. Microwave exposure alone did not significantly increase comet tail length compared with controls at 0 h or 21 h incubation. When lymphocytes were incubated with 30.00 micro mol/L or 3.00 micro mol/L MMC, microwave exposure significantly increased comet tail lengths compared with MMC alone. Combinations of microwave with BLM or MMS did not produce significantly greater DNA damage than BLM or MMS alone.
