Cook A, Woodward A, Pearce N, Marshall C. · 2003
Researchers investigated whether trends in tumour incidence rates in New Zealand varied since the introduction of cellular telephones in 1987. The exposure measure was the proportion of cellular telephone subscribers within the national population. They compared trends in tumour rates at anatomical sites receiving high, medium, and low levels of cellular telephone radiation based on dosimetry data. Graphs for high, medium, and low exposure sites showed no significant changes in trend patterns for either gender from 1986 to 1998. Incidence rates for head and neck malignancies, including sites hypothetically receiving the highest radiofrequency radiation, did not change materially after cellular telephone introduction.
Jarupat S, Kawabata A, Tokura H, Borkiewicz A. · 2003
The study aimed to investigate effects of the 1900 MHz electromagnetic field emitted from a cellular phone on nocturnal melatonin secretion. Exposure to cellular phone EMF caused a significant reduction in salivary melatonin in female human subjects.
Hocking B, Gordon I. · 2003
The authors examined survival of 123 children with acute lymphatic leukemia in an inner ring and an outer ring of municipalities around television towers in North Sydney, Australia. The inner ring included 29 cases with 16 deaths, while the outer ring included 94 cases with 34 deaths. Five-year survival was 55% in the inner ring and 71% in the outer ring, and 10-year survival was 33% versus 62%. The adjusted mortality rate ratio for the inner ring compared to the outer ring was 2.1 with a 95% confidence interval of 1.1 to 4.0. The difference in survival was statistically significant with a log-rank test p-value of 0.03 and a Wilcoxon test p-value of 0.05.
Hardell L et al. · 2003
The aim of the study was to investigate vestibular schwannoma, tinnitus, and cellular telephones. An increased odds ratio of 3.45 with a 95% confidence interval of 1.77-6.76 was found for vestibular schwannoma associated with analogue cell phone use. The age-standardized incidence of vestibular schwannoma in Sweden increased significantly by 2.53% per year from 1960 to 1998, with the increase only significant in the period 1980-1998.
Hardell L, Mild KH, Carlberg M. · 2003
Researchers conducted a case-control study of 1,617 patients aged 20-80 with histopathology-verified brain tumours diagnosed from 1997 to 2000, each matched to a control from the Swedish Population Register. Tumours in the temporal area on the same side as phone use had higher risk for analogue phones (OR=2.3, 95% CI=1.2-4.1), acoustic neurinoma risk was OR=4.4 (95% CI=2.1-9.2) for analogue users, and risk rose per year of analogue use (OR=1.04 per year, 95% CI=1.01-1.08).
Ha M, Lim HJ, Cho SH, Choi HD, Cho KY. · 2003
Desta AB, Owen RD, Cress LW. · 2003
Researchers exposed L929 murine fibroblast cells to radiofrequency radiation from a time division multiple access wireless phone operating at 835 MHz to determine the effect on ornithine decarboxylase activity. Exposure lasted 8 hours at average specific absorption rates ranging from less than 1 W/kg up to 15 W/kg, after which cells were harvested and ODC activity was measured. No statistically significant difference in ODC activity was found between exposed and sham-exposed cells at non-thermal specific absorption rates. At SARs that caused measurable heating, a dose-dependent decrease in enzymatic activity was observed and was consistent with a comparable decrease caused by non-RF-radiation heating.
Anane R et al. · 2003
Researchers tested whether whole-body exposure to GSM-900 microwaves affected tumor promotion and progression in female Sprague-Dawley rats with DMBA-induced mammary tumors. Results were negative for tumor latency, multiplicity, and volume, though in the first experiment tumor incidence was higher at 1.4 W/kg but less so at 2.2 W/kg and not at all at 3.5 W/kg. Overall the results were considered rather inconsistent and did not bring new evidence of a co-promoting effect of GSM-900 exposure.
Mashevich M et al. · 2003
Researchers examined whether in vitro exposure of human peripheral blood lymphocytes to continuous 830 MHz electromagnetic fields causes losses and gains of chromosomes, a condition called aneuploidy. Cells were irradiated at SAR levels ranging from 1.6 to 8.8 W/kg for 72 hours. A linear increase in chromosome 17 aneuploidy was observed as a function of the SAR value, which the researchers described as a genotoxic effect. Control experiments conducted without any RF radiation across a temperature range of 34.5 to 38.5 °C showed that elevated temperature was not associated with the increased aneuploidy or the changes in centromeric DNA replication seen after RF exposure.
Unknown authors · 2002
Unknown authors · 2002
Female Sprague Dawley rats were MF or sham exposed for 2 weeks at a flux density of 100 microTesla. Proliferation of epithelial cells in the mammary tissue and adjacent skin was examined by in vivo labeling with bromodeoxyuridine (BrdUrd) and in situ labeling of Ki-67 protein by the antibody MIB-5. MF exposure significantly enhanced BrdUrd and Ki-67 labeling in the mammary epithelium, indicating a marked increase in cell proliferation. Melatonin levels in pineal or mammary glands were not affected by MF exposure. Topical application of 12-O-tetradecanoylphorbol-13-acetate increased BrdUrd and Ki-67 labeling in skin epithelial cells, particularly hair follicles, but not in mammary tissue.
Unknown authors · 2002
Unknown authors · 2002
The paper estimates the annual number of excess illness cases that might occur near high-voltage powerlines in the UK. Within 150m of powerlines, magnetic field exposures above 0.1 microT are postulated to result in 9000 excess cases of depression in adults and 60 cases of suicide. Within 400m of powerlines, this may result annually in 200-400 excess cases of lung cancer, 2000-3000 cases of other illnesses associated with air population and 2-6 cases of childhood leukaemia. Seventeen cases of non-melanoma skin cancer might occur by exposure directly under powerlines.
Unknown authors · 2002
Researchers measured magnetic fields and two sources of contact current in 36 homes in Pittsfield, MA. The first source, VP–W, is the voltage due to current in the grounding wire, and the second, VW–E, is the voltage between the water pipe and earth.
Unknown authors · 2002
Takahashi S et al. · 2002
Researchers investigated the mutagenic potential of 1.5 GHz electromagnetic near fields using brain tissues of Big Blue mice. Male BBM were locally exposed to EMF in the head region at 2.0, 0.67, and 0 W/kg specific absorption rate for 90 min/day, 5 days/week, for 4 weeks. There was no significant variation in the frequency of independent mutations of the lacI transgene in the brains. Deletion mutations were slightly increased in both the high and low EMF exposure groups as compared with the sham-exposed group, but the differences were not statistically significant.
Johansen C et al. · 2002
The study aimed to investigate mobile phones and malignant melanoma of the eye. The researchers compared incidence rates of this rare cancer with the number of mobile phone subscribers in Denmark and found no increasing trend in melanoma incidence, in sharp contrast to the exponentially increasing number of subscribers starting in the early 1980s.
Zheng T, Blair A, Zhang Y, Weisenburger DD, Zahm SH · 2002
Researchers analyzed data from two population-based case-control studies of non-Hodgkin's lymphoma performed in Kansas and Nebraska. The analysis included 555 incident NHL cases, 56 CLL cases, and 2380 population-based controls. In men, agricultural, forestry, and logging industries were associated with an odds ratio of 1.6 for NHL and CLL. Risks increased with duration of employment and appeared to vary by histological type of NHL.
Richter ED, Berman T, Levy O · 2002
The authors reported on five young patients who developed brain tumors within 10 years of initial occupational radar exposure. Four of the patients were less than 30 years old at the time of diagnosis.
Muscat JE et al. · 2002
The hypothesis that intracranial energy deposition from handheld cellular telephones causes acoustic neuroma was tested in an epidemiologic study of 90 patients and 86 control subjects. The relative risk was 0.9 (p = 0.07) and did not vary significantly by the frequency, duration, and lifetime hours of use. In patients who used cellular telephones, the tumor occurred more often on the contralateral than ipsilateral side of the head. Further efforts should focus on potentially longer induction periods.
Michelozzi P et al. · 2002
Researchers conducted an ecological study near the Vatican Radio station in Rome to evaluate leukemia mortality in adults and childhood leukemia incidence. The study area within 10 km had 49,656 residents, with 40 adult leukemia deaths (1987–1998) and eight childhood leukemia cases (1987–1999). Childhood leukemia risk was elevated within 6 km (standardized incidence rate 2.2, 95% CI 1.0–4.1). Risk declined significantly with distance for both male adult mortality (p=0.03) and childhood leukemia (p=0.036). The authors noted limitations including small case numbers and lack of exposure data, and stated no causal implication can be drawn.
Leszczynski D, Joenväärä S, Reivinen J, Kuokka R · 2002
Researchers exposed human endothelial EA.hy926 cells to 900 MHz GSM mobile phone radiation for 1-hour and observed changes in phosphorylation of many proteins. The exposure transiently increased phosphorylation of hsp27 and altered expression levels of hsp27 and p38MAPK, and this phosphorylation increase was prevented by a p38MAPK inhibitor. The culture temperature remained at 37 +/- 0.3 degrees C throughout the exposure, confirming non-thermal effects. The authors hypothesized that mobile phone radiation-induced activation of hsp27 may facilitate brain cancer by inhibiting the cytochrome c/caspase-3 apoptotic pathway and increase blood-brain barrier permeability by stabilizing endothelial cell stress fibers.
Hardell L, Mild KH, Carlsberg M. · 2002
Researchers conducted a case-control study of 649 patients aged 20-80 with malignant brain tumours diagnosed between 1997 and 2000 in Sweden, matched with controls from the Swedish Population Register. Overall, no significantly increased risks were found for analogue, digital, or cordless phone use.
Hardell L et al. · 2002
Researchers conducted a case-control study of 1617 patients aged 20 to 80 with histopathologically verified brain tumours diagnosed between 1997 and 2000 in Sweden. Exposure to analogue cellular telephones was assessed by questionnaire and showed an overall increased odds ratio of 1.3 for brain tumours. The risk was higher for tumours on the same side of the head as phone use (OR 2.5) and for acoustic neurinoma (OR 3.5), while no clear association was found for digital or cordless phones.
Hallberg O, Johansson O. · 2002
Researchers extracted exposure-time-specific incidence from exposure and incidence data from 4 different countries and compared it with reported age-specific incidence of melanoma. The exposure-time-specific incidence from all 4 countries became almost identical and approximately equal to the reported age-specific incidence of melanoma. A correlation was found between melanoma incidence and the number of locally receivable FM transmitters.
