Adair ER et al. · 2005
Researchers measured thermoregulatory responses in six adult volunteers during 45-minute whole-body exposures to 220 MHz radio frequency energy at three power densities and three ambient temperatures. Esophageal temperature showed small changes of no more than 0.35 °C and never exceeded 37.3 °C under any test condition. Vigorous sweating occurred at PD = 12 and 15 mW/cm(2), with sweating levels higher than those observed for equivalent PD at 100 MHz. The researchers concluded that exposed subjects thermoregulate efficiently through increased heat loss responses, particularly sweating.
Diem E, Schwarz C, Adlkofer F, Jahn O, Rudiger H. · 2005
Researchers exposed cultured human diploid fibroblasts and transformed GFSH-R17 rat granulosa cells to 1800 MHz RF-EMF at SAR levels of 1.2 or 2 W/kg, using both intermittent and continuous exposures. DNA strand breaks were determined by means of the alkaline and neutral comet assay. Effects occurred after 16 h exposure in both cell types, and intermittent exposure showed a stronger effect in the comet assay than continuous exposure. The researchers concluded that the induced DNA damage cannot be based on thermal effects.
Hutter HP, Moshammer H, Wallner P, Kundi M. · 2004
Researchers surveyed neighbors of cell towers (n = 123, response rate approx. 48%) and medical students (n = 366) about environmental health risks including mobile telecommunication. Neighbors rated health risks for both mobile phones and cell towers higher than students did. The magnitude of perceived risks resembled that of other ubiquitous exposures like traffic noise and air pollution.
Capri M et al. · 2004
Researchers studied whether prolonged in vitro exposure to 1800 MHz radiofrequency could affect human peripheral blood mononuclear cells from young and elderly donors by altering apoptosis, mitochondrial membrane potential, and heat shock protein 70 levels. Three GSM signal modulations (Basic, DTX, and Talk) were applied at specific absorption rates of 1.4 and 2.0 W kg−1. Endpoints were analyzed both with and without the apoptosis-inducing agent 2-deoxy-D-ribose. No significant difference was found between RF-exposed and sham-exposed cells for any endpoint. The 1800 MHz RF did not induce apoptosis on its own, did not alter apoptosis triggered by an agent, and did not change mitochondrial function or HSP 70 expression.
Lagroye I et al. · 2004
The study aimed to investigate the effect of 2450 MHz pulsed-wave microwaves on DNA damage in rat brain cells and whether proteinase K is needed to detect such damage. Rats exposed to γ-rays showed significant DNA damage using both comet assay versions independent of proteinase K. Neither assay version detected any difference in comet length or normalized comet moment between sham-exposed and microwave-exposed rats regardless of proteinase K inclusion. No DNA damage was detected in brain cells after exposure to 2450 MHz pulsed-wave microwaves at 1.2 W kg−1 regardless of proteinase K inclusion. The results support the conclusion that low-level 2450 MHz pulsed-wave microwave exposures do not induce DNA damage detectable by the alkaline comet assay.
Tafforeau M et al. · 2004
Researchers exposed flax seedlings to 105 GHz radiation from a Gunn oscillator for 2 hours at non-thermal levels. The exposure induced meristem production with kinetics similar to those induced by weak environmental stresses and GSM phone radiation.
Panagopoulos DJ, Karabarbounis A, Margaritis LH · 2004
The study used GSM mobile phones with a carrier frequency at 900 MHz. Insects were exposed to the near field of the mobile phone antenna for 6 minutes per day during the first 2–5 days of adult life. Modulated radiation decreased reproductive capacity by 50–60% while nonmodulated radiation decreased it by 15–20%. The authors suggested the radiation decreases the rate of cellular processes during gonad development.
Nylund R, Leszczynski D · 2004
Researchers exposed the human endothelial cell line EA.hy926 to mobile phone radiation and examined protein expression using two-dimensional electrophoresis. Up to 38 proteins showed statistically significant changes in expression levels after irradiation. Four proteins were identified by mass spectrometry, including two isoforms of the cytoskeletal protein vimentin.
Czyz J et al. · 2004
Researchers exposed wild-type and p53-deficient embryonic stem cells to GSM-217 and GSM-Talk modulated electromagnetic fields at 1.71 GHz. GSM-217 exposure significantly increased hsp70 mRNA levels in p53-deficient cells, with a transient rise in c-jun, c-myc, and p21 levels only in those cells. GSM-Talk exposure produced no gene expression changes in either cell type, and cardiac differentiation and cell cycle were unaffected by GSM-217.
Kim MJ, Rhee SJ. · 2004
Researchers exposed rats to 2.45 GHz microwave radiation for 15 minutes and then fed them diets containing 0%, 0.25%, or 0.5% catechin. Microwave exposure increased cytochrome P450 levels by 85% and NADPH-cytochrome P450 reductase activity by 29% compared with normal rats. It also raised superoxide radical concentrations by 35% and decreased superoxide dismutase activity by 34% and glutathione peroxidase activity by 28%. Catechin supplementation at 0.25% and 0.5% lowered superoxide radicals by 11% and 12%, increased superoxide dismutase activity by 19% and 25%, and kept glutathione peroxidase near normal.
Vorobyov V, Pesic V, Janac B, Prolic Z. · 2004
Researchers exposed rats repeatedly for three days to low-intensity 915 MHz microwaves modulated at 4 Hz and recorded EEG from the somatosensory cortex. Microwave exposure alone significantly enhanced fast EEG rhythms (18-30 Hz), an effect not seen in sham-exposed or radiation-naïve rats. In microwave-exposed rats, scopolamine did not cause the EEG slowing observed in non-exposed rats, and its effect resembled that of physostigmine in naive animals.
Paulraj R, Behari J · 2004
Protein kinase C activity was measured in whole brain, hippocampus, and whole brain minus hippocampus after exposure. A significant decrease in enzyme level was observed in exposed rats compared to sham-exposed rats.
Koyama S, Isozumi Y, Suzuki Y, Taki M, Miyakoshi J. · 2004
Researchers exposed Chinese hamster ovary CHO-K1 cells to 2.45-GHz electromagnetic fields for 2 hours at SARs of 5, 10, 20, 50, 100, and 200 W/kg to study micronucleus formation. Micronucleus frequency in cells exposed at SARs lower than 50 W/kg did not differ from sham-exposed controls. At SARs of 100 and 200 W/kg, micronucleus frequency was significantly higher than in sham-exposed controls. The researchers also found that micronucleus frequency increased in a temperature-dependent manner when cells were heat-treated at temperatures from 38 to 42 degrees C.
Aksen F, Dasdag S, Akdag MZ, Askin M, Dasdag MM. · 2004
Researchers exposed rats to radiofrequency radiation from cellular phones to study effects on trace elements, T1 relaxation times, and rectal temperature. Manganese and zinc levels in the serum of exposed rats were significantly different from the control group. Iron, copper, and T1 relaxation times in serum did not change significantly, and rectal temperature also showed no statistically significant difference between groups.
Zmyslony M, Politanski P, Rajkowska E, Szymczak W, Jajte J. · 2004
Researchers tested whether 930 MHz continuous wave electromagnetic radiation affects reactive oxygen species (ROS) levels in rat lymphocytes. Acute exposure of 5 and 15 minutes did not affect ROS levels on its own. When iron ions were added to stimulate ROS production, the ROS level was significantly greater in exposed lymphocytes after both exposure durations.
Port M, Abend M, Romer B, Van Beuningen D. · 2003
Researchers exposed human leukemia HL-60 cells in vitro to high-frequency electromagnetic fields 25 times higher than ICNIRP occupational reference levels. Cells were harvested at 0, 24, 48, and 72 hours after exposure, and apoptosis, micronuclei, abnormal cells, and expression of 1176 genes were measured. No significant changes were found in apoptosis, micronucleation, abnormal cells, or differential gene expression.
Navarro EA, Sequra J, Portoles M, Gomez-Perretta de Mateo C · 2003
Researchers conducted a health survey near a cellular phone base station operating at DCS-1800 MHz in Murcia, Spain. Statistical analysis showed a significant correlation between declared symptom severity and measured power density, and the higher exposure group reported increased severity.
Jayanand, Behari J, Lochan R. · 2003
Researchers exposed rats with sciatic neurectomy-induced osteoporosis to modulated pulsed electromagnetic fields at a 14 MHz carrier frequency modulated at 16 Hz with 10 V peak-to-peak amplitude. The exposure produced a statistically significant increase in bone mineral density and a deceleration in the bone resorption process in the femur and tibia. The authors suggest that this effective window of pulsed radio frequency fields may be used therapeutically for osteoporosis treatment.
Dabrowski MP et al. · 2003
Researchers exposed cultured human blood mononuclear cells isolated from 16 healthy donors to 1300 MHz pulse-modulated microwaves at a power density of 10 W/m2 and a SAR of 0.18 W/kg. Lymphocyte proliferative responses and IL-2 receptor saturation did not change, though lymphocyte production of IL-10 increased (P < .001). Monocyte production of IL-1β increased significantly (P < .01), the concentration of its antagonist IL-1ra dropped by half (P < .01), and TNF-α remained unchanged. The researchers concluded that pulse-modulated microwaves represent the potential of immunotropic influence, stimulating preferentially the immunogenic and proinflammatory activity of monocytes at relatively low levels of exposure.
Mashevich M et al. · 2003
Researchers examined whether in vitro exposure of human peripheral blood lymphocytes to continuous 830 MHz electromagnetic fields causes losses and gains of chromosomes, a condition called aneuploidy. Cells were irradiated at SAR levels ranging from 1.6 to 8.8 W/kg for 72 hours. A linear increase in chromosome 17 aneuploidy was observed as a function of the SAR value, which the researchers described as a genotoxic effect. Control experiments conducted without any RF radiation across a temperature range of 34.5 to 38.5 °C showed that elevated temperature was not associated with the increased aneuploidy or the changes in centromeric DNA replication seen after RF exposure.
Shckorbatov YG et al. · 2002
Researchers used intracellular microelectrophoresis to study electrokinetic properties of nuclei in human buccal epithelial cells after microwave exposure at wavelengths of 8 mm and 16 mm with a surface power density of 0.2 mW/cm(2). Microwave irradiation for 15-60 s induced ENN changes, decreasing ENN when it was initially elevated and increasing it when initially low. No significant difference between the action of microwaves of wavelengths of 8 mm and 16 mm was found. Microwave exposure increased membrane permeability for the in vivo dye indigo Carmine in cells from all donors regardless of initial ENN levels.
Pakhomov AG, Gaj ek P, Allen L, Stuck BE, Murphy MR · 2002
Researchers compared bioeffects of continuous wave and extremely high power pulse microwaves at 9.3 GHz and 1.25 W average power using yeast cell density in agarose gel. Cell density was strongly affected by irradiation and correlated with local temperature rise, but no statistically significant difference between CW and EHPP was found across the SAR range. A trend (P<0.1) for a difference appeared at average SAR of 100 W/kg and higher, corresponding to peak SAR above 20 MW/kg for EHPP.
Tat FH, Wah KC, Hung YH. · 2002
Researchers tested three Personal Communication System cellular phones at different distances from multiple electronic medical devices and measured electromagnetic field strength with a spectrum analyser. Only the CO2 airway adapter and the haemoglucostix meter were affected, and only when the phone was in very close proximity. Compared to a 1997 study of Global System for Mobile Communication phones, the Personal Communication System phones generated less electromagnetic interference. The authors recommended a much larger study and an accurate international electromagnetic interference standard before any change in hospital policy on mobile phone usage.
Vangelova K, Israel M, Mihaylov S. · 2002
Researchers studied 12 male satellite station operators during 24-hour shifts and compared them with 12 unexposed controls. Exposure was low-level with specific absorption of 0.1127 J.kg-1. Exposed operators had significantly increased 24-hour excretion of 11-OCS and disrupted circadian rhythm, including increased mesor, decreased amplitude, and shifted acrophase. Catecholamine excretion rates also changed significantly with greater variability.
Stopczyk D et al. · 2002
Researchers assessed the effect of mobile phone electromagnetic fields on SOD-1 activity and MDA level in human blood platelets exposed to 900 MHz for 1, 3, 5, and 7 minutes. SOD-1 activity was significantly depleted after 1, 5, and 7 minutes of exposure and increased after 3 minutes compared with controls. MDA concentration increased significantly after 1, 5, and 7 minutes and decreased after 3 minutes compared with controls. The authors concluded that oxidative stress from microwave exposure may cause adverse cellular changes and systemic disturbances.
