Masoumi A, Karbalaei N, Mortazavi SMJ, Shabani M. · 2018
The Wi-Fi exposure used a frequency of 2.45 GHz. The Wi-Fi exposed group had significantly lower weight gain than controls and developed hyperglycemia. Plasma insulin levels and glucose-stimulated insulin secretion from pancreatic islets were significantly reduced, while pancreatic lipid peroxidation increased and GSH, SOD, and GPx activities decreased.
Kamali K, Taravati A, Sayyadi S, Gharib FZ, Maftoon H. · 2018
Researchers exposed male Wister rats to 2.45 GHz Wi-Fi radiation continuously for 10 weeks. Total antioxidant capacity of plasma and activities of CAT, GSH-Px, and SOD decreased significantly in exposed rats. GST activity increased significantly in the exposed group. GSH and TBARS levels did not change significantly after exposure.
Gupta SK, Mesharam MK, Krishnamurthy S. · 2018
Male rats were exposed to EMR (900, 1800 and 2450 MHz) every day for 1 h for 28 consecutive days. Animals exposed to EMR-2450 MHz exhibited significant cognitive deficits. EMR-2450 MHz caused loss of mitochondrial function and integrity, an increase in amyloid beta expression. There was release of cytochrome-c and activation of apoptotic factors such as caspase-9 and -3 in the hippocampus. Further, there was decrease in levels of acetylcholine, and increase in activity of acetyl cholinesterase, indicating impairment of cholinergic system.
Yakymenko I et al. · 2018
Researchers used developing quail embryos to assess the oxidative and mutagenic effects of GSM 1800 MHz microwave radiation from a commercial smartphone. The embryos were exposed in ovo to 0.32 µW/cm2, discontinuously, for 5 days before and 14 days through the incubation period. Exposure resulted in a 2-fold increase in superoxide generation rate, an 85% increase in nitrogen oxide generation rate, and up to twice increased levels of 8-oxo-dG in cells of 1-day old chicks from the exposed embryos. The exposure also resulted in a significant, almost twice, increase of embryo mortality.
Talebnejad MR et al. · 2017
Researchers exposed 40 adult white New Zealand rabbits to GSM-simulated microwave radiation at distances of 10 cm or 30 cm for one or three days. Electroretinography responses measured seven days after exposure showed no statistically significant differences between any groups. Retinal tissue appeared normal without degeneration, but ciliary body congestion occurred more often in rabbits receiving higher microwave doses.
Park J, Kwon JH, Kim N, Song K · 2017
Researchers exposed HT22 mouse hippocampal neuronal cells and SH-SY5Y human neuroblastoma cells to 1950 MHz RF-EMF at a SAR of 6 W/kg for 2 hours per day over 3 days. They analyzed mRNA and protein expression of key genes involved in Aβ processing. In HT22 cells, mRNA levels of APP, BACE1, ADAM10 and PSEN1 decreased, while APP mRNA was unchanged in SH-SY5Y cells. Protein expression of APP and BACE1 and secreted Aβ peptide did not differ significantly between exposed and control cells.
Yilmaz A et al. · 2017
Pregnant rats were exposed to 900 MHz EMF for 24 hours a day over 20 days using a digital signal generator placed under the cage. Livers and blood were collected from male and female offspring 60 days after birth for biochemical and histopathological analysis. Liver malondialdehyde levels increased significantly while glutathione levels decreased significantly, and serum ALT and AST levels were significantly elevated. Liver sections showed intense hepatocyte degeneration with cytoplasmic eosinophilic structures, pyknotic nuclei, and fibrosis. The researchers concluded that intrauterine EMF exposure causes harmful liver effects that persist into adulthood.
Lian HY, Lin KW, Yang C, Cai P. · 2017
Researchers exposed two budding yeast strains, NT64C and SB34, to 2.0 GHz RF-EMF and 50 Hz ELF-EMF. Both RF-EMF and ELF-EMF exposure elevated the de novo generation and propagation of the yeast prion [URE3] in the two strains. The increase grew over time, and ELF-EMF showed a dose-dependent effect. Chaperone transcription and expression (Hsp104, Hsp70-Ssa1/2, Hsp40-Ydj1) did not change significantly after exposure. ROS levels and SOD and CAT activities rose after short-term exposure but not after long-term exposure.
de Oliveira FM, Carmona AM2 Ladeira C. · 2017
To test whether mobile phone-associated EMF exposure affects micronucleus frequency in exfoliated buccal cells, the researchers obtained cell smears from the left and right inner cheeks of 86 healthy mobile phone users aged 18-30 who completed a characterization survey. No relationship was observed between micronucleus frequency and duration of mobile phone use in daily calls. Cells on the same side as phone use did not show a statistically significantly higher micronucleus frequency compared to cells on the opposite side. A highly statistically significant increase in micronucleus frequency was found in subjects reporting regular exposure to genotoxic agents.
Zothansiama, Zosangzuali M, Lalramdinpuii M, Jagetia GC. · 2017
The study compared 40 individuals living within 80 meters of mobile phone base stations with a control group living 300 meters away, matched for age, gender, diet, smoking, alcohol, and mobile phone use. Radiofrequency power density was significantly higher in the exposed group. The exposed group showed a significantly higher frequency of micronuclei. Plasma antioxidants glutathione, catalase, and superoxide dismutase were significantly reduced, and lipid peroxidation was increased in the exposed group. Multiple linear regression showed that higher RF power density was associated with lower antioxidant levels, higher micronuclei frequency, and higher lipid peroxidation.
Varghese R, Majumdar A, Kumar G, Shukla A. · 2017
Researchers exposed female Sprague Dawley rats to 2.45GHz radiation for 4 hours per day for 45 days and assessed behavioral and oxidative stress parameters. Exposed rats exhibited memory decline and anxiety behavior in the Morris water maze, elevated plus maze, and light-dark box tests. Radiation exposure decreased brain antioxidant enzymes superoxide dismutase, catalase, and reduced glutathione, increased lipid peroxidation, and increased the apoptotic marker caspase 3, while histopathological examination and TNF-α levels showed no significant changes.
Türedi S, Kerimoğlu G, Mercantepe T, Odacı E. · 2017
Malondialdehyde levels increased in the EMF group compared to both control and sham groups in kidney and bladder tissues, while catalase and glutathione levels decreased. Kidney tissue in the EMF group showed dilatation and vacuolization in tubules, glomerular degeneration, and increased apoptotic cells. Bladder tissue in the EMF group showed degeneration in the transitional epithelium, stromal irregularity, and increased apoptotic cells. Transmission electron microscopy revealed glomerular capillary degeneration with capillary basement membranes in the EMF group.
Mortazavi SMJ et al. · 2017
Researchers divided 50 rats into five groups and pre-exposed three groups to 915 MHz radiofrequency radiation for 4 hours daily over one week at low, medium, and high power. Twenty-four hours after the last exposure, the rats were given a 4 Gy sublethal gamma radiation dose and sacrificed after 5 hours. Pre-exposure increased glutathione levels and glutathione reductase activity in liver, with glutathione increases only in the low power group and glutathione reductase activity increases in both low and medium power groups. The elevated antioxidant levels protected liver tissue from oxidative damage induced by the gamma radiation.
Chandel S, Kaur S, Singh HP, Batish DR, Kohli RK · 2017
Researchers exposed onion roots to 2100 MHz electromagnetic field radiation for 1, 2, and 4 hours in a single day. The exposure increased levels of malondialdehyde, hydrogen peroxide, and superoxide anion, indicating oxidative stress. Antioxidant enzymes superoxide dismutase and catalase showed increased activity in response.
Gökçek-Saraç Ç et al. · 2017
Rats were exposed to 900 and 2100 MHz RF-EMR for 2 h/day for either 1 week (acute) or 10 weeks (chronic). The study measured hippocampal levels and activity of PKA, CaMKIIα, CREB, and p44/42 MAPK from NMDAR-related signaling pathways using Western blotting and activity assays. Chronic exposure produced significantly higher enzyme levels than acute exposure at both frequencies, and 2100 MHz exposure produced higher levels than 900 MHz in both acute and chronic groups.
Zhang KY et al. · 2017
Researchers exposed mouse spermatocyte-derived GC-1 cells to a 1950 MHz RF field at 3 W/kg SAR for 24 hours with or without 6 Gy X-ray irradiation. RF exposure alone did not change cell proliferation or apoptosis levels. When combined with X-ray, RF exposure significantly decreased proliferation and increased apoptotic rate compared to X-ray alone. The combined exposure also significantly decreased Bcl-2 protein expression and increased Bax protein expression.
Roser K et al. · 2017
Researchers measured personal RF-EMF exposure in 90 adolescents aged 13 to 17 years using a portable ExpoM-RF device across 13 frequency bands from 470 to 3600 MHz for three consecutive days with a time-activity diary. Mobile phones contributed 67.2% and mobile phone base stations contributed 19.8% of total personal RF-EMF measurements averaging 63.2 μW/m² (0.15 V/m). WLAN at school and home accounted for 3.5% of total personal measurements. Environmental sources contributed on average 6.0% to the brain dose and 9.0% to the whole-body dose according to dose calculations.
Marjanovic Cermak AM, Pavicic I, Trosic I · 2017
Human neuroblastoma SH-SY5Y cells were exposed to 1800 MHz radiofrequency radiation for 10, 30, and 60 minutes at an electric field strength of 30 V m-1 and a specific absorption rate of 1.6 W kg-1. Cell viability remained within normal physiological values after radiation exposure. Significantly higher ROS levels were observed at every radiation exposure time tested. After 60 minutes of exposure, the radiation caused significant lipid and protein damage. The highest glutathione concentration was detected after 10 minutes of exposure.
Kim JH, Kim HJ, Yu DH, Kweon HS, Huh YH, Kim HR. · 2017
Researchers studied the effects of RF-EMF exposure on synaptic vesicles in the cortical neurons of mice. C57 BL/6 mice were exposed to 835 MHz RF-EMF at 4.0 W/kg SAR for 5 hours daily. The density of synaptic vesicles was significantly decreased in the presynaptic boutons of cortical neurons after exposure. The expression of synapsins I/II genes and proteins was also significantly decreased in exposed mice.
Hedendahl LK, Carlberg M, Koppel T, Hardell L. · 2017
Eighteen teachers from seven schools carried a body-borne exposimeter in school to measure radiofrequency radiation exposure. The mean exposure to RF radiation ranged from 1.1 to 66.1 µW/m² across the schools. The highest mean level recorded was 396.6 µW/m² during 5 minutes of a lesson when the teacher let students stream and watch YouTube videos.
Marjanovic Cermak AM et al. · 2017
Researchers exposed V79 fibroblast cells to 1800 MHz RF radiation for 10, 30, and 60 minutes at a specific absorption rate of 1.6 W/kg to investigate possible links between radiofrequency exposure and oxidative stress. Cell viability remained within normal physiological values regardless of exposure time. An increased level of superoxide radicals was detected after 60-minute exposure, and a significantly higher GSH level was observed immediately after 10-minute exposure, though GSH-Px activity was higher but not significant. Lipid oxidative damage in exposed cell samples was not observed.
Bourdineaud JP et al. · 2017
Researchers exposed Eisenia fetida earthworms to electromagnetic fields at 900 MHz and field levels ranging from 10 to 120 V m-1 for a period of two hours. All exposure treatments induced significant DNA modifications, and the number of probe hybridisation sites showed a significant two-fold decrease even after 24 hours of recovery. Genes involved in general stress, oxidative stress, and immune defence were up-regulated after exposure, and Western blots confirmed an increased quantity of HSP70 and MTCO1 proteins.
Waldmann-Selsam C et al. · 2016
A long-term field monitoring study from 2006 to 2015 in Bamberg and Hallstadt, Germany, included 144 radiofrequency measurements at 1.5m height in streets and parks. Researchers selected 60 damaged trees, 30 randomly selected trees, and 30 trees in low-radiation areas. Measurements revealed significant differences in power flux density between the damaged side facing a phone mast and the opposite side, and between the exposed side of damaged trees and all other groups. Trees in low-radiation areas with no visual contact to phone masts and power flux density under 50μW/m2 showed no damage.
Singh K et al. · 2016
The study aimed to compare health complaints and salivary flow rates between populations living near and far from mobile phone base stations in Jaipur, India. Sleep disturbances were assessed using the Pittsburgh Sleep Quality Index and other health problems were recorded via questionnaire. A majority of residents near the base stations reported sleep disturbances, headache, dizziness, irritability, concentration difficulties, and hypertension. Stimulated salivary secretion was significantly lower in the exposed group compared to controls (P < 0.01). The authors concluded that prolonged exposure effects cannot be ruled out and further studies are warranted.
Shekoohi Shooli F et al. · 2016
In this study 30 male Wistar rats were randomly divided into three groups of ten. The control group received no radiation, the sham group was exposed to a switched-off jammer, and the exposure group was placed 50 cm from the jammer after a 12-hour fast. A statistically significant difference was observed between the control and exposure groups at 24, 48, and 72 hours (p <0.001, <0.001, and 0.002), while no significant difference was found between control and sham groups.
