3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.
Research Guide

5G vs 4G Radiation: What's Different?

Based on 653 peer-reviewed studies

Share:

People often ask whether 5G is more dangerous than 4G. This question requires understanding how 5G technology differs from previous generations and what research exists on each.

5G networks operate across multiple frequency bands. Low-band 5G (600-900 MHz) is actually similar to 4G frequencies. Mid-band 5G (2.5-4 GHz) overlaps with existing WiFi. High-band 5G (24-40+ GHz, "millimeter wave") represents the newest frequencies for consumer wireless exposure.

This page compares what research shows about radiation exposure from 5G versus 4G technologies.

Key Research Findings

  • 5G uses multiple frequency bands with different characteristics
  • Millimeter waves (high-band 5G) penetrate less deeply into tissue
  • More cell towers can actually reduce individual exposure levels

Related Studies (653)

Radiofrequency radiation injures trees around mobile phone base stations.

Waldmann-Selsam C et al. · 2016

German researchers studied 120 trees near cell phone towers over nine years and found that trees closest to the towers developed damage on the side facing the antenna, while trees in low-radiation areas showed no damage. The damage patterns directly correlated with radiofrequency radiation measurements, with higher exposure levels corresponding to more severe tree damage. This suggests that RF radiation from cell towers can cause biological harm to living organisms at environmental exposure levels.

Cell phone use is associated with an inflammatory cytokine profile of parotid gland saliva.

Siqueira EC et al. · 2016

Researchers analyzed saliva from the parotid glands (located near the jaw) in 83 people who regularly use cell phones, comparing the side exposed to phone radiation with the unexposed side. They found that the exposed side showed signs of inflammation, with decreased levels of an anti-inflammatory protein and increased levels of a pro-inflammatory protein. The inflammatory changes were more pronounced in people who had used cell phones for over 10 years, suggesting cumulative effects from long-term exposure.

Apoptotic cell death during Drosophila oogenesis is differentially increased by electromagnetic radiation depending on modulation, intensity and duration of exposure.

Sagioglou NE et al. · 2016

Greek researchers exposed fruit flies to radiofrequency radiation at various frequencies (100-900 MHz) and found that all exposure protocols increased cell death in developing eggs, even at very low power levels. The study revealed that frequency-modulated signals caused more damage than continuous waves, and that biological effects don't follow a simple dose-response relationship. This research demonstrates that even brief exposures to RF radiation can disrupt normal cellular processes in developing organisms.

Survival Assessment of Mouse Preimplantation Embryos After Exposure to Cell Phone Radiation

Safian F et al. · 2016

Iranian researchers exposed mouse embryos to cell phone radiation (900-1800 MHz) for 30 minutes daily during their first four days of development. While the embryos still developed normally to the blastocyst stage, they showed significantly higher cell death rates and reduced cell viability compared to unexposed embryos. This suggests that cell phone radiation may damage developing embryos even when overall development appears normal.

Metabolomic study of urinary polyamines in rat exposed to 915 MHz radiofrequency identification signal.

Paik MJ, Kim HS, Lee YS, Do Choi H, Pack JK, Kim N, Ahn YH · 2016

Researchers exposed rats to 915 MHz radiofrequency signals (like those from RFID tags) for 8 hours daily over 2 weeks and analyzed chemical changes in their urine. They found significant alterations in polyamines, which are molecules involved in cellular metabolism and growth. The RF-exposed rats showed a 54% increase in one specific polyamine compared to just 17% in control animals, suggesting the radiofrequency exposure disrupted normal cellular processes.

Evidence of cellular stress and caspase-3 resulting from a combined two-frequency signal in the cerebrum and cerebellum of sprague-dawley rats.

López-Furelos A et al. · 2016

Spanish researchers exposed rats to cell phone frequencies (900 MHz and 2450 MHz) for 1-2 hours and found significant cellular stress in brain tissue 24 hours later. The study measured heat shock proteins (stress markers) and caspase-3 (a protein involved in cell death) in different brain regions. Surprisingly, when rats were exposed to both frequencies together, the effects weren't simply additive, suggesting that multiple EMF signals interact with brain tissue through complex mechanisms we don't fully understand.

Effects of long-term pre- and post-natal exposure to 2.45 GHz wireless devices on developing male rat kidney.

Kuybulu AE et al. · 2016

Researchers exposed pregnant rats and their offspring to 2.45 GHz wireless radiation (the same frequency used by WiFi and microwaves) and found significant kidney damage in the young rats. The exposed animals showed increased oxidative stress (cellular damage from harmful molecules), reduced antioxidant defenses, and visible tissue damage in their kidneys. This suggests that EMF exposure during pregnancy and early development may harm kidney function in developing organisms.

Effects of radiofrequency field exposure on glutamate-induced oxidative stress in mouse hippocampal HT22 cells.

Kim JY, Kim HJ, Kim N, Kwon JH, Park MJ. · 2016

Researchers exposed mouse brain cells to radiofrequency radiation while also treating them with glutamate, a brain chemical that becomes toxic in Alzheimer's disease. While RF exposure alone had minimal effects, it significantly amplified the damage when combined with glutamate, increasing cell death and harmful oxidative stress. This suggests that RF radiation may worsen brain cell vulnerability in conditions like Alzheimer's disease.

Dielectric characterization of healthy and malignant colon tissues in the 0.5-18 GHz frequency band.

Fornes-Leal A et al. · 2016

Researchers measured the electrical properties of healthy and cancerous colon tissue samples from 20 patients across frequencies used by cell phones, WiFi, and other wireless devices (0.5-18 GHz). They found that cancerous tissue had significantly different electrical characteristics than healthy tissue, with cancer tissue showing 8.8% higher dielectric constant values. This discovery could lead to new methods for early cancer detection using electromagnetic waves.

Effects of exposure to 2100MHz GSM-like radiofrequency electromagnetic field on auditory system of rats.

Çeliker M et al. · 2016

Researchers exposed rats to 2100 MHz radiofrequency radiation (similar to 3G cell phone signals) for 30 days to study effects on hearing. While the rats' hearing tests showed no functional changes, microscopic examination revealed increased cell death and degeneration in the brain areas that process sound. This suggests that cell phone radiation may damage auditory neurons even before hearing loss becomes detectable.

Effects of radiation from a radiofrequency identification (RFID) microchip on human cancer cells

Lai HC, Chan HW, Singh NP · 2016

Researchers exposed three different types of human cancer cells to radiofrequency energy from RFID microchips for one hour and found that the RF energy killed or slowed the growth of all cancer cell types tested. The effect was blocked when cells were pretreated with compounds that prevent oxidative damage, suggesting the RF energy works by generating harmful free radicals through a chemical process called the Fenton Reaction.

Effects of radiofrequency field exposure on glutamate-induced oxidative stress in mouse hippocampal HT22 cells

Kim JY, Kim HJ, Kim N, Kwon JH, Park MJ · 2016

Scientists exposed mouse brain cells to radiofrequency radiation and glutamate, a brain chemical that becomes toxic during diseases like Alzheimer's. RF exposure alone caused minimal harm, but when combined with glutamate, it dramatically increased cell death, suggesting RF radiation may worsen brain damage in diseased conditions.

Effects of exposure to 2100 MHz GSM-like radiofrequency electromagnetic field on auditory system of rats

Çeliker M et al. · 2016

Turkish researchers exposed rats to cell phone radiation at 2100 MHz for 30 days to study effects on hearing. While the rats' hearing tests showed no changes, microscopic examination revealed significant damage to brain cells in the auditory system, including increased cell death and degeneration. This suggests that cell phone radiation may harm the hearing system in ways that don't show up immediately in standard hearing tests.

Activity and expression of acetylcholinesterase in PC12 cells exposed to intermittent 1.8 GHz 217-GSM mobile phone signal.

Valbonesi P, Franzellitti S, Bersani F, Contin A, Fabbri E. · 2016

Italian researchers exposed rat brain cells to cell phone radiation at the legal safety limit for 24 hours and found that a key brain enzyme called acetylcholinesterase increased by 40%. This enzyme is crucial for memory, learning, and proper brain function, and disruptions to it are linked to neurodegenerative diseases like Alzheimer's.

Effects of 3G cell phone exposure on the structure and function of the human cytochrome P450 reductase.

Tanvir S et al. · 2016

French researchers exposed a key human enzyme called cytochrome P450 reductase to cell phone radiation (1966 MHz) for 60 minutes at 5 watts per kilogram. The radiation changed the enzyme's structure and reduced its activity by 22% compared to unexposed controls. This enzyme is critical for drug metabolism and detoxification in the liver, suggesting cell phone radiation could potentially interfere with how our bodies process medications and toxins.

Mobile phone signal exposure triggers a hormesis-like effect in Atm+/+ and Atm-/- mouse embryonic fibroblasts.

Sun C, Wei X, Fei Y, Su L, Zhao X, Chen G, Xu Z · 2016

Researchers exposed mouse embryonic cells to 1,800 MHz radiofrequency radiation (similar to cell phone signals) at high power levels for 1-12 hours and found it initially caused DNA breaks. However, after prolonged exposure, the cells' DNA repair systems became so active that DNA damage dropped below normal background levels - a phenomenon called hormesis where low doses of a harmful substance trigger beneficial protective responses.

Effects of RF-EMF Exposure from GSM Mobile Phones on Proliferation Rate of Human Adipose-derived Stem Cells: An In-vitro Study.

Shahbazi-Gahrouei D, Hashemi-Beni B, Ahmadi Z. · 2016

Researchers exposed human fat-derived stem cells to radiation from GSM mobile phones (900 MHz frequency) for different durations over 5 days. They found that exposure for 9 minutes or longer per day significantly reduced the cells' ability to grow and multiply, while 6 minutes per day showed no effect. This suggests that even brief daily phone exposure can impair the regenerative cells your body uses for healing and tissue repair.

GSM 900 MHz Microwave Radiation-Induced Alterations of Insulin Level and Histopathological Changes of Liver and Pancreas in Rat.

Mortazavi SM et al. · 2016

Researchers exposed rats to cell phone radiation (GSM 900 MHz) for either 3 or 6 hours daily over 7 days to study effects on insulin production and organ health. While insulin levels remained unchanged, the radiation caused inflammatory damage in the liver and harmed insulin-producing cells in the pancreas, with longer exposure times producing more severe damage.

Induction of Poly(ADP-ribose) Polymerase in Mouse Bone Marrow Stromal Cells Exposed to 900 MHz Radiofrequency Fields: Preliminary Observations.

He Q, Sun Y, Zong L, Tong J, Cao Y. · 2016

Researchers exposed mouse bone marrow cells to cell phone-level radiation for three hours daily over five days. The cells showed significant increases in PARP-1, a protein that repairs DNA damage, suggesting the radiation triggered cellular stress requiring DNA repair mechanisms.

Effect of Radiofrequency Radiation on Human Hematopoietic Stem Cells.

Gläser K et al. · 2016

German researchers exposed human blood stem cells (the cells that create all blood cells in your body) to cell phone radiation at three different frequencies for up to 66 hours. They tested multiple biological endpoints including DNA damage, cell death, and oxidative stress. Surprisingly, they found that GSM radiation actually caused a small decrease in DNA damage compared to unexposed cells, while showing no other significant effects.

Glial markers and emotional memory in rats following acute cerebral radiofrequency exposures.

Barthélémy A et al. · 2016

Researchers exposed rats to radiofrequency radiation for 15 minutes at different intensities and measured brain inflammation and memory function. They found that even low-level exposure (1.5 W/kg) caused significant brain inflammation, while higher exposure (6 W/kg) impaired long-term memory and increased inflammation in multiple brain regions. This study provides direct evidence that brief RF exposure can trigger brain inflammation and memory problems in living animals.

Mobile phone signal exposure triggers a hormesis-like effect in Atm+/+ and Atm-/- mouse embryonic fibroblasts.

Sun C, Wei X, Fei Y, Su L, Zhao X, Chen G, Xu Z. · 2016

Scientists exposed mouse cells to cell phone radiation and discovered it initially damaged DNA but then activated repair systems that left cells healthier than unexposed ones. This "hormesis" effect had never been seen with phone radiation before, suggesting potential protective cellular responses.

Adaptive response in mouse bone-marrow stromal cells exposed to 900-MHz radiofrequency fields: Gamma-radiation-induced DNA strand breaks and repair.

Ji Y, He Q, Sun Y, Tong J, Cao Y. · 2016

Chinese researchers exposed mouse bone marrow cells to cell phone-level radiofrequency radiation (900 MHz) for 4 hours daily over 5 days, then hit them with gamma radiation to damage their DNA. Surprisingly, the cells that received RF preconditioning showed less DNA damage and repaired themselves faster than cells exposed to gamma radiation alone, suggesting RF exposure may trigger protective cellular responses.

Improved Mitochondrial and Methylglyoxal-Related Metabolisms Support Hyperproliferation Induced by 50 Hz Magnetic Field in Neuroblastoma Cells.

Falone S et al. · 2016

Researchers exposed human neuroblastoma cells (a type of brain cancer cell) to 50 Hz magnetic fields at 1 milliTesla and found the fields made the cancer cells grow faster and become more aggressive. The magnetic field exposure triggered protective mechanisms in the cancer cells that helped them survive and multiply more effectively. This suggests that power frequency magnetic fields might promote the growth of existing brain tumors.

Further Reading

For a comprehensive exploration of EMF health effects and practical protection strategies, explore these books by R Blank and Dr. Martin Blank.