Tang J et al. · 2015
Researchers exposed 108 male Sprague-Dawley rats to a 900 MHz, 1 mW/cm2 electromagnetic field for 14 or 28 days at 3 hours per day, with some rats left unexposed as a sham group. Rats exposed for 28 days crossed platforms less often and spent less time in the target quadrant than rats exposed for 14 days and unexposed rats. Twenty-eight days of exposure was also associated with cellular edema, neuronal cell organelle degeneration, and albumin and HO-1 extravasation in the hippocampus and cortex. The researchers found that 28 days of EMF exposure induced the expression of mkp-1, resulting in ERK dephosphorylation.
Narayanan SN, Kumar RS, Karun KM, Nayak SB, Bhat PG · 2015
Lee D, Lee J, Lee I. · 2015
Researchers tracked the movement of 10 pairs of guppies and 15 pairs of zebrafish in a fish tank under a cell phone-generated RF EMF. Fish locomotion was observed under normal conditions, in the visual presence of a cell phone, after feeding, and under starvation. Fish locomotor behavior was random both in normal conditions and in the presence of an off-signaled cell phone, but there were significant changes in locomotion after feeding under the RF EMF. The researchers also demonstrated that temperature elevation caused by the cell phone was not relevant to the observed effects.
Senavirathna MD, Asaeda T, Thilakarathne BL, Kadono H · 2014
Researchers investigated the effect of EMR on the growth dynamics of Myriophyllum aquaticum by measuring nanometric elongation rate fluctuation using a statistical interferometry technique. Plants were exposed to 2 GHz EMR at a maximum of 1.42 Wm(-2) for 1 hour. After continuous exposure, M. aquaticum plants exhibited a statistically significant 51 ± 16% reduction in NERF standard deviation. Temperature observations revealed that EMR exposure did not cause dielectric heating, so the reduced NERF was due to a non-thermal effect. The alteration in NERF continued for at least 2.5 hours after exposure with no significant recovery during the experimental period.
Rougier C, Prorot A, Chazal P, Leveque P, Leprat P · 2014
Researchers investigated the effects of 2.45 GHz microwave exposure on Escherichia coli cell membranes while maintaining the suspension at an average temperature of 37°C. No effect was detected with conventional heating or 200 W exposure, but membrane integrity was slightly altered at powers from 400 to 2000 W. Thermal characterization indicated the temperature reached was not high enough to explain the membrane changes, suggesting a power-dependent electromagnetic threshold effect. Exposures were discontinuous to keep the average temperature at 37°C, and effects were measured using flow cytometry with propidium iodide staining and intracellular protein release.
Khalil AM, Abu Khadra KM, Aljaberi AM, Gagaa MH, Issa HS. · 2014
The study aimed to examine oxidant and antioxidant status in saliva of cell phone users by collecting samples before and after 15- and 30-minute calls. Saliva was analyzed for malondialdehyde, 8-oxo-dG, and antioxidant capacities using ORAC and HORAC assays. Mean 8-oxo-dG and protein concentrations peaked at 15 minutes, while HORAC, ORAC, and MDA levels increased progressively and reached maximum at 30 minutes. Talking time had no significant effect on 8-oxo-dG, MDA, ORAC, or HORAC levels. The authors concluded that there is no relationship between radiofrequency radiation exposure and changes in the salivary oxidant/antioxidant profile.
de Souza FT et al. · 2014
Researchers investigated whether cell phone use alters the expression of gene products related to cellular stress in parotid glands. They used saliva from 62 individuals, comparing the gland exposed to cell phone radiation (ipsilateral) to the unexposed contralateral gland. No differences were found in salivary flow, total protein concentration, p53, p21, ROS, GSH, heat shock proteins 27 and 70, or IgA, even when grouping by years of use or monthly call minutes.
Kang KA et al. · 2014
Researchers exposed U87, PC12, and SH-SY5Y neuronal cells to combined radiofrequency radiation at 837 MHz CDMA and 1950 MHz WCDMA with a specific absorption rate of 2 W/kg each for 2 hours. They also tested co-exposure with hydrogen peroxide or menadione and measured intracellular reactive oxygen species using flow cytometry with a fluorescent probe. Combined RF radiation alone did not consistently affect ROS levels in a time-dependent manner, and co-exposure with hydrogen peroxide or menadione showed no statistically significant change compared to the chemicals alone.
Sepehrimanesh M et al. · 2014
Twenty adult male Sprague-Dawley rats were exposed to 900 MHz RF-EMF for 1, 2, or 4 hours per day over 30 days, with a sham-exposed control group. At the end of the experiment, the long-time exposure group showed significantly higher FSH and LH levels than the sham group. The long-time exposure group also had significantly increased activin B and prolactin, decreased inhibin B compared to sham and short-time exposure groups, and decreased testosterone compared to short- and moderate-time exposure groups.
Sasaki K, Wake K, Watanabe S · 2014
Previous measurements of skin dielectric properties typically included all three skin layers together. This study provides new data for the epidermis and dermis measured in vitro from 0.5 GHz to 110 GHz. The results agreed with Gabriel's data for the dermis up to 20 GHz. For 20 to 100 GHz, experimental results showed larger values than extrapolated Gabriel data. For frequencies over 20 GHz, the parametric model tends toward the experimental results for the epidermis.
Mortazavi SM et al. · 2014
Researchers previously found that radiofrequency radiation exposure can induce a survival adaptive response in laboratory animals. They also reported that pre-exposing mice to GSM mobile phone radiation increased resistance to subsequent Escherichia coli infection. In this study, animals receiving both radiofrequency pre-exposure and bacterial challenge had a 56% survival rate versus 20% for those receiving only the bacterial challenge.
Geronikolou S et al. · 2014
Egg laying in the second generation was compared between exposed and non-exposed cultures using advanced statistics. The 900 MHz exposure showed statistical significance, while the cordless phone exposure showed limited statistical significance. The researchers also calculated and simulated the near-field radiation patterns inside the vials. They found that the power difference between the two fields becomes null when the cylinder radius and antenna height increase.
Aydogan F et al. · 2014
Thirty Wistar albino rats were divided into four groups. Groups A and B served as control groups for 10 days and 40 days with six rats each, while groups C and D were exposure groups with nine rats each. The rats were exposed to 2100 MHz radiofrequency radiation simulating a third generation mobile phone for 6 hours per day, 5 days per week, for 10 or 40 days. Exposure groups showed numerous histopathological changes in the parotid gland, with more prominent changes after 40 days compared to 10 days.
Tök L, Nazıroğlu M, Doğan S, Kahya MC, Tök O. · 2014
Thirty-two rats were randomly assigned to four groups, with one group exposed to Wi-Fi at 2.45 GHz for 60 minutes daily over 30 days and another group receiving melatonin during the same exposure. Lipid peroxidation was slightly higher in the Wi-Fi group than in controls, and glutathione peroxidase activity was significantly lower in the Wi-Fi group. Melatonin supplementation significantly decreased lipid peroxidation and increased both glutathione peroxidase activity and reduced glutathione levels compared with the Wi-Fi group.
Luo YP, Ma HR, Chen JW, Li JJ, Li CX. · 2014
Researchers randomly assigned 40 male SD rats to a normal control group, a model group, a Shuifei Jibin Capsule group, and an American Ginseng Capsule group, with 10 rats each. Rats in the model, SJC, and AGC groups were exposed to imitated 900 MHz cellular phone radiation for 4 h in 12 consecutive days, while the normal control group was not irradiated. Compared to the normal control, the model group showed hepatocyte nuclear atrophy, increased liver MDA and Nrf2 protein, and decreased SOD and GSH. In the SJC group, liver MDA and Nrf2 decreased and SOD, GSH, and GSH-PX increased; in the AGC group, MDA and Nrf2 decreased and SOD and GSH increased.
Seckin E et al. · 2014
Pregnant rats and their offspring were exposed to 900 MHz and 1800 MHz Global System for Mobile Communications radiofrequency radiation for one hour per day during pregnancy and for 21 days after birth. Distortion product otoacoustic emission tests showed no significant difference among the groups. Electron microscopy revealed significant differences in the numbers of normal, apoptotic, and necrotic cells among the groups. The findings indicated cellular structural damage in the cochlea caused by radiofrequency radiation exposure during cochlear development.
Lv B, Su C, Yang L, Xie Y, Wu T · 2014
Researchers recruited ten subjects for a crossover, double-blind experiment with real and sham LTE EMF exposure sessions. Each session involved 30 minutes of LTE EMF exposure (power on or off) while EEG signals were recorded from 32 channels. The study found that short-term LTE EMF exposure modulated synchronization patterns of EEG activation across the whole brain.
Valbonesi P, Franzellitti S, Bersani F, Contin A, Fabbri E. · 2014
Researchers exposed rat PC12 cells to 1.8 GHz continuous wave or GSM-modulated signals at a SAR of 2 W/kg for 4, 16, or 24 hours. HSP70 gene expression was measured by RT-PCR, while HSP70 protein and MAPK phosphorylation were measured by Western blotting. Only the GSM-217Hz signal increased HSP70 transcription after 16 or 24 hours of exposure. HSP70 protein levels and three MAPK signaling pathways were unchanged by any of the signals.
Tas M et al. · 2014
The study used 14 adult Wistar Albino rats divided into sham and exposure groups of seven each. Exposed rats received 900 MHz RF radiation from a GSM signal generator for 3 hours per day, 7 days a week, for one year. No differences were found in sperm motility or concentration between groups. Exposed rats had higher rates of morphologically normal sperm but lower tunica albuginea thickness and Johnsen testicular biopsy scores.
Taberski K et al. · 2014
Researchers exposed 16 male Djungarian hamsters to 900 MHz GSM-modulated RF-EMF at SAR levels of 0, 0.08, 0.4, and 4 W/kg for one week per condition. Only at the highest SAR level did fur temperature increase by about 0.5°C, food consumption decrease, and daytime carbon dioxide production and respiratory quotient decrease.
Sannino A et al. · 2014
Researchers exposed human peripheral blood lymphocytes from four healthy donors to 1950 MHz radiofrequency fields at 0.3 W/kg for 20 hours, then challenged them with 1.0 or 1.5 Gy X-irradiation. After 72 hours of culture, they measured micronuclei incidence and found a significant decrease in micronuclei in cells exposed to both radiofrequency fields and X-rays compared to X-rays alone. The results suggested a radiofrequency-induced adaptive response and resistance to subsequent X-ray damage, though variability between donors was observed.
Qin F et al. · 2014
Ozgur E, Guler G, Kismali G, Seyhan N · 2014
Researchers exposed Hep G2 hepatocarcinoma cells to intermittent 900- and 1800-MHz radiofrequency radiation at a specific absorption rate of 2 W/kg for 1, 2, 3, or 4 hours. Cell viability changed according to the frequency and duration of the exposure. Four-hour exposure produced more pronounced effects than shorter durations. 1800-MHz radiation had a larger impact on cell viability and injury than 900-MHz radiation. Morphological analysis showed irregular nuclei and DNA damage after 4 hours of 1800-MHz exposure.
Li WH, Li YZ, Song DD, Wang XR, Liu M, Wu XD, Liu XH. · 2014
Researchers pretreated rat MMECs with CRT (25 pg/mL) for 12 hours then exposed them to 2.856 GHz radiation at 30 mW/cm2 for six minutes. Microwave radiation increased LDH leakage, apoptosis rate, and decreased cell viability in MMECs. Microwave radiation also induced ER stress characterized by increased GRP78 and CRT expression and upregulation of CHOP and Bax with downregulation of Bcl-2. Exogenous CRT pretreatment attenuated MR-induced apoptosis, LDH leakage, ER stress, and ER stress-related apoptotic signaling.
Le Quément C et al. · 2014
Researchers exposed human skin cell lines to 60.4 GHz millimeter waves at incident power densities ranging from 1 to 20 mW/cm(2). The expression of ER stress sensors BIP and ORP150 was examined by real-time RT-PCR. MMW radiation did not change basal levels of BIP or ORP150 mRNA across any cell line, exposure duration, or power density. At 20 mW/cm(2), MMW exposure inhibited thapsigargin-induced overexpression of BIP and ORP150. This inhibition was attributed to thermal effects from the MMW exposure.
