Indulski JA, Makowiec-Dabrowska T, Zmyslony M, Siedlecka J · 1997
The authors reviewed epidemiological data on the relationship between reproductive disorders and electromagnetic field exposure from power lines, industrial devices, medical appliances, video display terminals, and household devices. The analyzed studies examined effects on female and male reproduction, including spontaneous abortion, stillbirth, premature birth, low birth weight, congenital malformations, and progeny gender proportion among occupationally exposed persons.
Nelson BK, Conover DL, Shaw PB, Snyder DL, Edwards RM · 1997
Researchers exposed pregnant rats to radiofrequency radiation that raised colonic temperature to 42.0°C for 10 minutes while administering various doses of 2-methoxyethanol on gestation day 13. Dose-related developmental toxicity from 2-methoxyethanol occurred both with and without the radiation exposure. However, the radiation changed the shape of the dose-effect curve for 2-methoxyethanol.
Magras, IN, Xenos, TD · 1997
Researchers measured RF power densities between 168 nW/cm2 and 1053 nW/cm2 at several locations around an antenna park. Twelve pairs of mice divided into two groups were placed in locations of different power densities and mated five times. The number of newborns per dam decreased progressively until irreversible infertility occurred, but crown-rump length, body weight, and vertebral counts improved.
Nakamura H, Seto T, Nagase H, Yoshida M, Dan S, Ogino K. · 1997
Pregnant rats exposed to microwaves showed a significant reduction in splenic natural killer cell activity, while no such reduction was seen in exposed virgin rats. Corticosterone and ACTH increased, and oestradiol decreased, in both exposed virgin and pregnant rats, while beta-endorphin and progesterone increased significantly only in pregnant rats.
Jensh RP · 1997
This review examined whether chronic prenatal microwave exposure in rats caused adverse effects at birth or alterations in offspring development and growth. Pregnant rats were exposed throughout pregnancy to continuous wave 915 MHz, 2450 MHz, or 6000 MHz radiation at power density levels of 10, 20, or 35 mW/cm2, respectively. Animals exposed to 915 MHz did not exhibit any consistent significant alterations in any of the parameters measured. Offspring exposed to 6000 MHz showed an initial slight but significant retardation in term weight, delayed eye opening, lower weekly weights that recovered by the fifth week, and changes in water T-maze and open field performance.
Kubinyi G, Thuroczy G, Bakos J, Boloni E, Sinay H, Szabo LD, · 1996
Pregnant CFLP mice were exposed to 2.45 GHz microwave radiation for 100 minutes each day throughout gestation in an anechoic chamber. Brain aminoacyl-tRNA synthetase activity decreased significantly after continuous-wave exposure but not after amplitude-modulated exposure. Liver enzyme activity increased after both continuous-wave and amplitude-modulated exposure, while body and organ weights were unaffected.
Yoshida Y et al. · 1995
Researchers exposed pregnant rats to whole-body microwaves at 10 mW/cm2 and 2,450 MHz and measured placental blood flow and five endocrine indicators. Placental blood flow at 45-90 minutes after exposure was significantly decreased in exposed rats. Microwave exposure increased corticosterone and decreased estradiol regardless of angiotensin II pretreatment, increased progesterone and prostaglandin F2 alpha without pretreatment, and did not change prostaglandin E2. Pretreatment with angiotensin II increased placental blood flow at 15 and 30 minutes, but this effect was absent in microwave-exposed rats.
Nelson BK et al. · 1994
Researchers exposed rats to RF radiation that maintained colonic temperature at 42.0 degrees C for 0, 10, 20, or 30 min and to 2ME at doses of 0, 75, 100, 125, or 150 mg/kg on gestation days 9 or 13. Fetuses were examined on gestation day 20 for external, skeletal, and visceral malformations. Synergistic effects were observed for some treatment combinations but not others, with highly significant effects on gestation day 13 but little effect on day 9. Statistical analyses showed no global synergistic effect but evidence of synergism at intermediate dose levels.
Guberan E et al. · 1994
Researchers mailed a questionnaire to 2846 female Swiss physiotherapists and analyzed 1781 pregnancies. The gender ratio was 107 for 508 pregnancies exposed to shortwave radiation and 101 for 1273 unexposed pregnancies. There was no trend in gender ratio with increasing intensity or duration of exposure. Low birthweight prevalence was not related to exposure for either boys or girls. The findings of the Danish study could not be confirmed.
Ouellet-Hellstrom R, Stewart WF · 1993
Researchers mailed questionnaires to 42,403 physical therapists in 1989 and used a nested case-control design with 1,753 miscarriage cases matched to 1,753 controls. A pregnancy was considered exposed if the mother reported using microwave or shortwave diathermy in the six months before or during the first trimester. Microwave use was associated with increased miscarriage odds (OR 1.28, 95% CI 1.02-1.59) with a dose-response trend, while shortwave diathermy was not associated (OR 1.07, 95% CI 0.91-1.24).
Fukui Y, Hoshino K, Inouye M, Kameyama Y · 1992
Researchers exposed pregnant mice to 2.45 GHz microwave radiation for 15 or 20 minutes on day 13 of gestation. Pyknotic cell incidence in the ventricular zone was 1.83% after 15 minutes and 3.06% after 20 minutes of microwave exposure. Microwave radiation for 20 minutes produced effects comparable to immersion in 42°C hot water for 15 minutes. Brain weight was significantly lower and neuron density higher in the 20-minute exposure group compared to controls. The researchers concluded that microwave radiation at the tested dose mainly has a thermal effect.
Larsen AI · 1991
Researchers conducted a case-referent study using a cohort of Danish physiotherapists linked to national pregnancy registers to assess the relation between high-frequency electromagnetic radiation exposure and congenital malformations. Exposure during the first month of pregnancy was assessed through blinded telephone interviews without knowledge of case status. No statistically significant associations were found between pregnancy outcome and high-frequency electromagnetic radiation exposure (odds ratio 1.7, 95% confidence interval 0.6-4.3).
Larsen AI, Olsen J, Svane O · 1991
Case groups were spontaneous abortions, low birth-weight prematurity, and stillbirth or death within one year, and exposure was assessed by telephone interviews. Highly exposed mothers had only 23.5% male births, a statistically significantly altered gender ratio showing a dose-response pattern. High-frequency electromagnetic radiation was associated with low birthweight, but only for male newborns.
Nelson BK et al. · 1991
The exploratory study aimed to determine whether concurrent exposure to RF radiation and 2-methoxyethanol enhances developmental toxicity in rats. In the primary study, pregnant rats were exposed to RF radiation sufficient to raise rectal temperature to 42.0°C for 30 minutes and given 150 mg/kg 2-methoxyethanol by gavage, and the combination raised mean fetal malformations per litter to 76% from 14% with 2ME alone and 30% with RF alone. The severity of malformations also increased with the combination, scoring 6 on a relative severity scale compared with less than 1 for 2ME alone and 3 for RF alone.
Louis Slesin · 1984
The article reviews concerns about radiation from video display terminals (VDTs) in the workplace. VDTs emit very low frequency (VLF) radiation from the flyback transformer at about 16,000 pulses per second. The VLF pulses are similar in shape and intensity to those that caused adverse effects on chick embryos in Delgado's laboratory. Eleven clusters of problem pregnancies and miscarriages have been reported among women working on or near VDTs in the U.S. and Canada.
Charles Wallach · 1982
Prolonged CRT use is associated with eye, nose, throat, and skin irritations, headaches, dizziness, nausea, pain, malaise, and premature births or miscarriages. The author proposes that the high positive surface charge on CRT screens neutralizes negative ions, increases positive ion concentrations, and repels airborne particles toward operators.
Roberts Rugh, Edward I. Ginns, Henry S. Ho, William M. Leach · 1975
Researchers exposed individual CF1 mice to 2450 MHz microwave radiation in a waveguide with controlled temperature, humidity, and air flow. Female mice in estrus had a lower average lethal absorbed dose (10.65 cal/g) than those in diestrus (11.50 cal/g). Pregnant mice exposed on gestation day 8 showed teratogenic effects including exencephalies, hemorrhages, resorptions, stunting, and fetal death at absorbed doses of 3 to 8 cal/g, and the response was not all-or-none. As absorbed dose increased, the probability of at least one exencephaly per litter increased, but the relationship was not linear and varied widely among litters. A total of 1096 mice were exposed and monitored individually.
W. Ludwig, M. A. Persinger, K.-P. Ossenkopp · 1973
Researchers exposed rats prenatally to a 0.5 Hz, 0.5—30 gauss rotating magnetic field and observed behavioral and physiological changes. Prenatally exposed rats showed less ambulatory behavior and greater defecation in an open field test. In a free-operant avoidance task, exposed rats pressed the lever significantly less but received similar numbers of shocks as controls. Exposed rats also had significantly increased relative thyroid and testicle weights, with no changes in blood sugar or eosinophil counts.
Dietzel F, Kern W, Steckenmesser R · 1972
Researchers exposed 749 pregnant rats to a single abdominal short-wave treatment during the first 16 days of pregnancy, raising rectal temperatures to about 40° within 10 minutes. Treatment on the first two days of pregnancy caused 65% embryo deaths compared to 25% in controls. Embryonic injuries occurred only when maternal rectal temperature reached at least 40° for 10 minutes; lower temperatures caused no injuries.
Unknown authors
Female Sprague-Dawley rats were exposed to 2.45 GHz continuous-wave microwaves at 28 mW/cm² for 100 minutes daily from days 6 to 15 of pregnancy. The study included 67 sham-irradiated and 70 irradiated females, resulting in 64 and 66 pregnancies respectively. No significant differences were found in pregnancy rates, litter size, or the incidence of external, visceral, or skeletal anomalies between the groups. In a separate experiment, 35% of adult rats exposed to 40 mW/cm² died from hyperthermia.
W.D. Travers, R.J. Vetter
Researchers randomly assigned pregnant rats to six groups and exposed them daily for 15 days to 0, 5, or 25 mW/cm² of 2450 MHz microwave radiation for 10 or 20 minutes. Blood samples were taken before exposure on day 5 and on days 10, 15, and 20 of pregnancy to measure serum iron, unsaturated iron binding capacity, and total iron binding capacity. Total iron binding capacity increased with higher power densities, and significant differences were found between power densities, sampling days, and exposure durations. Rats exposed to 25 mW/cm² for 20 minutes showed a statistically significant increase in total iron binding capacity, while control and low-exposure groups initially dropped.
Unknown authors
Researchers exposed eight pregnant rats to 500 uW/cm² 2450 MHz microwaves for 20 hours a day during the first 19 days of gestation. Exposed litters had seven times more neonatal deaths than controls, and pups weighed less on day 7 and opened their eyes one day later. Prenatally exposed females showed accelerated growth between 40 and 60 days of age and maintained a 10% higher body weight into adulthood.
Unknown authors
Researchers exposed eight pregnant rats to 2450-MHz microwaves at 500 μW/cm² for 20 hours daily during the first 19 days of gestation, which reduced the dams' percentage body weight gain compared to sham-exposed controls. During the first week of life, prenatally exposed offspring had a sevenfold higher mortality, lower body weights, and delayed eye opening compared to controls. Exposed female offspring showed accelerated growth after weaning, and as adults they exhibited more avoidance responses in a shuttlebox test and a disrupted colonic temperature rhythm.
Unknown authors
Twenty-four Wistar rats were exposed 8 hours daily throughout pregnancy to 2450 MHz microwave radiation at 20 mW/cm². The exposure was non-thermal because rectal temperatures did not rise above control levels. Half of the rats were evaluated for teratologic effects on day 22 of gestation, and the other half raised offspring for postnatal behavioral and physiological testing. No significant alterations in prenatal or postnatal growth and development were observed.
Unknown authors
Pregnant ICR mice were exposed to 2450 MHz continuous-wave radiation for 3 hours daily from gestational day 7 to 17 at an average power density of 10 mW/cm². Pups were tested from day 1 to day 21 postpartum using a battery of behavioral and neurological tests, all conducted blind. Exposed pups showed delayed initiation of several behavioral responses compared with sham-exposed pups. The delay affected the time needed for all exposed pups to achieve each response, but all exposed pups eventually reached the same developmental level as controls.
