Sauter C et al. · 2015
Researchers conducted a double-blind cross-over study with 30 healthy young men exposed to TETRA signals at 1.5 W/kg and 6.0 W/kg and sham. Exposure lasted 2.5 hours at 385 MHz with specific absorption rates of 1.5 and 6.0 W/kg. Attention was unchanged in two of three tasks, while working memory showed significant changes in two of four subtasks. 5 out of 35 tested parameters showed significant results, four of which indicated improved performance. Mood, well-being, and subjective somatic complaints were not affected by TETRA exposure.
Malek F, Rani KA, Rahim HA, Omar MH · 2015
The study aimed to determine whether short-term exposure at 1 V/m to typical GSM and UMTS signals affects cognitive performance and physiological parameters. The sample included 200 subjects, with 50.0% reporting idiopathic environmental intolerance attributed to electromagnetic fields (IEI-EMF) and 50.0% non-IEI-EMF. No statistically significant differences were found between real exposure and sham exposure for cognitive performance or physiological effects in either group (P’s > 0.05).
Zheng F et al. · 2015
Fatigue was significantly associated with years of MP usage and daily duration of MP calls, while headache was significantly associated with daily duration of MP calls. After adjusting for confounders, only the association between fatigue and MP usage remained statistically significant, and no significant association was found between MP use and other physical symptoms.
Geronikolou SA et al. · 2015
Schoeni A, Roser K, Röösli M · 2015
Researchers conducted a prospective cohort study with 439 adolescents who completed verbal and figural memory tasks at baseline and after one year. Wireless device use was assessed by questionnaire and operator recorded mobile phone use data for a subgroup of 234 adolescents, and RF-EMF dose measures for the brain and whole body were computed. Higher cumulative call duration and RF-EMF brain and whole-body doses were linked to lower figural memory scores. No exposure-response associations were observed for sending text messages and gaming, and memory change over one year was negatively associated with wireless phone use and more strongly with RF-EMF dose.
Zhao YL et al. · 2015
Mice were exposed to whole-body 2100 MHz microwaves at SARs of 0.45, 1.8, and 3.6 W/kg for 1 hour daily for 8 weeks. GO analysis showed the genes were involved in metabolic processes, cellular metabolic processes, regulation of biological processes, macromolecular metabolic processes, biosynthetic processes, cellular protein metabolic processes, transport, developmental processes, and cellular component organization. KEGG pathway analysis revealed enrichment in ribosome, Alzheimer's disease, Parkinson's disease, long-term potentiation, Huntington's disease, and Neurotrophin signaling pathways.
Zhang Y, Li Z, Gao Y, Zhang C. · 2015
Researchers investigated whether in utero exposure to 9.417-GHz microwave throughout gestation affected behavior in mouse offspring. Offspring showed less movement in the center of an open field and in an open arm of the elevated-plus maze, which the researchers interpreted as increased anxiety-related behavior. Offspring also showed reduced immobility in the tail suspension test and forced swimming test, which was interpreted as decreased depression-related behavior. In the Morris water maze, male offspring showed decreased learning and memory while female offspring were not affected, suggesting gender-dependent effects.
Tang J et al. · 2015
Researchers exposed 108 male Sprague-Dawley rats to a 900 MHz, 1 mW/cm2 electromagnetic field for 14 or 28 days at 3 hours per day, with some rats left unexposed as a sham group. Rats exposed for 28 days crossed platforms less often and spent less time in the target quadrant than rats exposed for 14 days and unexposed rats. Twenty-eight days of exposure was also associated with cellular edema, neuronal cell organelle degeneration, and albumin and HO-1 extravasation in the hippocampus and cortex. The researchers found that 28 days of EMF exposure induced the expression of mkp-1, resulting in ERK dephosphorylation.
Narayanan SN, Kumar RS, Karun KM, Nayak SB, Bhat PG · 2015
Deshmukh PS et al. · 2015
Researchers exposed male Fischer rats to microwave radiation for 180 days at 3 different frequencies, namely, 900, 1800 MHz, and 2450 MHz. The study investigated effects on cognitive function, heat shock protein 70 (HSP70), and DNA damage in rat brain. The results showed declined cognitive function, elevated HSP70 level, and DNA damage in the brains of microwave-exposed animals. The researchers concluded that chronic low-intensity microwave exposure in the frequency range of 900 to 2450 MHz may cause hazardous effects on the brain.
Hauri DD et al. · 2014
Researchers conducted a time-to-event analysis of children under 16 living in Switzerland on December 5, 2000, with follow-up until December 31, 2008. They also included an incidence density cohort of all children living in Switzerland for some time between 1985 and 2008. In the time-to-event analysis of 997 cancer cases, the adjusted hazard ratio for the highest exposure category was 1.03 for all cancers, 0.55 for childhood leukemia, and 1.68 for childhood CNS tumors. The incidence density analysis of 4,246 cancer cases showed similar results for all cancers and leukemia but did not indicate a CNS tumor risk, with an incidence rate ratio of 1.03.
Klose M et al. · 2014
Female Wistar rats from 14 days to 19 months were exposed in the head region for 2 hours per day, 5 days per week to a GSM-modulated 900 MHz field at SAR values of 0, 0.7, 2.5, and 10 W/kg. Four behavioral and learning tests (rotarod, Morris water maze, 8-arm radial maze, open field) were performed three times in juvenile, adult, and presenile rats. No profound differences were identified between exposure groups, though rotarod data showed significantly longer holding times for sham-exposed rats on some days, but these findings were not consistent. The results do not indicate harmful effects of long-term RF-EMF exposure begun at an early age on development, learning, and behavior, even at relatively high SAR values.
Trunk A et al. · 2014
Researchers recorded EEG and event-related potentials in an oddball paradigm during four sessions combining caffeine and UMTS mobile phone exposure. Caffeine significantly shortened reaction time and decreased the P300 area under the curve compared to control or mobile phone exposure alone. No effects on reaction time or P300 were observed for UMTS mobile phone exposure alone or combined with caffeine. The authors concluded no interactive or synergistic effects of caffeine and UMTS mobile phone exposure on neural or cognitive measures.
Chiu CT, Chang YH, Chen CC, Ko MC, Li CY. · 2014
Adachi-Mejia AM et al. · 2014
The study aimed to determine if mobile phones interfere with adolescent sleep, and researchers conducted a pilot test in a pediatric primary care practice with 454 patients aged 12 to 20 years, half female, attending a well-child visit. Adolescents completed paper-and-pencil surveys in the waiting room. More than half took their mobile phone to bed (62.9%) and kept it turned on while sleeping (56.8%). More than one-third texted after going to bed (36.7%), and 7.9% were awakened by a text two or more times per week. Almost half used their phone as their alarm (45.7%).
Zheng F et al. · 2014
A total of 7720 middle school students were involved in this cross-sectional study and 7102 valid questionnaires were obtained. Inattention was assessed using DSM-IV-TR criteria for the attention deficit component of ADHD. After adjusting for confounders, inattention was significantly associated with MP ownership, entertainment time on MP per day, MP position during the day, and MP mode at night. The strongest association was among students who spent more than 60 minutes per day playing on their MP.
Yogesh S, Abha S, Priyanka S. · 2014
The study enrolled 100 medical students divided into cases with more than two hours of daily mobile phone use (n=57) and controls with two hours or less (n=43), and assessed sleep quality using the Pittsburg Sleep Quality Index. Differences between groups were tested with the Mann-Whitney U test and Student's t-test, and correlations were analyzed using Spearman's rank correlation with significance set at p<0.05. Evening mobile phone use showed a significant negative association with sleep quality (r=-0.606, p=0.042), where higher PSQI scores indicate worse sleep.
Saikhedkar N et al. · 2014
Researchers exposed 30-day-old rats to 900 MHz radio waves from a mobile handset for 4 hours per day over 15 days. Exposed rats showed more anxiety and poor learning compared to control and sham groups. Antioxidant enzymes and non-enzymatic antioxidants changed significantly and lipid peroxidation increased in exposed rats.
Movvahedi MM et al. · 2014
Researchers enrolled 60 elementary school children aged 8 to 10 years in Shiraz, Iran. They used standardized computer-based tests of visual reaction time and short-term memory modified for children. Each test was repeated ten times in both real and sham exposure phases with a 30 min interval between phases. After a 10 min talk period, mean short-term memory scores were higher than after sham exposure (P = 0.030). Mean reaction times did not differ significantly between talk and sham exposure (P = 0.629).
Wang H et al. · 2014
Eighty Wistar rats were exposed to a 2.856 GHz pulsed microwave source at power densities of 0 mW/cm2 and 50 mW/cm2 for 6 minutes, and then observed at multiple time points up to 18 months after exposure. The microwave-exposed rats showed consistent deficiencies in spatial learning and memory. The level of amino acid neurotransmitters decreased after microwave radiation, and the ratio of glutamate and gamma-aminobutyric acid significantly decreased at 6 months. The hippocampus showed varying degrees of degeneration of neurons, and NR1 and NR2B expression showed a significant decrease, especially NR2B expression.
Schneider J, Stangassinger M · 2014
Researchers exposed male and female rats continuously to either 900-MHz GSM or 1.966-GHz UMTS electromagnetic fields at 0.4 W/kg. Memory was assessed using a social discrimination procedure, with differences in sniffing duration to familiar and novel juvenile rats used as the measure. EMF-exposed females showed no differences in sniffing duration compared with controls, but sniffing durations of EMF-exposed males at 3 months of age were significantly affected. At 6 months of age, GSM-exposed male adults showed a memory performance deficit, but UMTS-exposed males did not.
Razavinasab M, Moazzami K, Shabani M · 2014
Researchers exposed pregnant Wistar rats to 900 MHz pulsed-EMF irradiation for 6 hours per day during gestation, then tested the offspring using behavioral, histological, and electrophysiological methods. Mobile phone exposure was associated with a decrease in the number of action potentials fired and an increase in the amplitude of afterhyperpolarization in exposed offspring compared with controls. Phone exposure significantly altered learning acquisition and memory retention in both male and female offspring rats compared with control rats. Light microscopy of brain sections showed normal morphology in both control and mobile phone-exposed rats.
Qin F, Yuan H, Nie J, Cao Y, Tong J · 2014
Researchers exposed male mice to 1800 MHz radiofrequency fields at 208 microW/cm2 for 0, 30, or 120 minutes per day for 30 days, while some groups also received nano-selenium by intra-gastric injection. Significant impairments in learning and memory were observed in the RF 120 min group, along with reduced acetylcholine levels and antioxidant enzyme activity and increased GABA, glutamate, and MDA in the brain. Nano-selenium supplementation decreased GABA, glutamate, and MDA levels and increased acetylcholine levels and antioxidant enzyme activities in the exposed mice.
Qiao S et al. · 2014
Researchers exposed Wistar rats, rat hippocampal synaptosomes, and PC12 cells to microwave radiation for 5 minutes at a mean power density of 30 mW/cm2. Spatial learning and memory in rats was assessed using the Morris Water Maze navigation task, and there was a decrease in spatial memory performance after microwave exposure. The expression of phosphorylated synapsin I (ser-553) was decreased at 3 days post-exposure and elevated at later time points, while GABA release from synaptosomes was attenuated. Both microwave exposure and synapsin I silencing reduced GABA release, and the greatest reduction was found when both were combined, indicating a synergetic effect.
Li H et al. · 2014
Researchers exposed Wistar rats to 2.856 GHz microwaves at power densities of 5, 10, 20, or 30 mW/cm2 for 6 minutes three times a week for up to 6 weeks. Spatial learning and memory, hippocampus structure, brain electrical activity, and neurotransmitter levels were assessed at different time points after the last exposure. The study found dose-dependent memory deficits alongside inhibition of brain electrical activity, hippocampus neuron degeneration, and neurotransmitter disturbances. The researchers suggested that the serotonin system may be involved in the cognitive deficits seen after long-term microwave exposure.
