Open access paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585657/ -- Yorgancilar E et al. · 2017
Sixteen Wistar albino rats were divided into sham and exposure groups. The exposure group received 2.4 GHz RFR from a Wi-Fi generator for 24 h/day for one year at a distance of 50 cm. Distortion product otoacoustic emissions were measured at baseline, at 6 months, and at 12 months. At 6000 Hz, DPOAE values in the exposure group were lower than in the sham group and also lower at 12 months than at baseline and 6 months, while at 2000 Hz DPOAE values at 6 and 12 months were higher than baseline.
https://www.tandfonline.com/doi/full/10.1080/13102818.2017.1373033 -- Topsakal S et al. · 2017
Sixteen Wistar albino rats were divided into sham and exposure groups, with the exposure group receiving 2.4 GHz RFR from a Wi-Fi generator 24 hours per day for one year at a distance of 50 cm. Distortion product otoacoustic emissions (DPOAE) were measured at baseline, 6 months, and 12 months. At 6000 Hz, DPOAE values were lower in the exposure group than in the sham group, and at 12 months they were also lower than baseline and 6-month values; at 2000 Hz, DPOAE values at 6 and 12 months were higher than baseline.
Altuntas G et al. · 2017
The study was a single-center, prospective, randomized, double-blinded trial involving 30 emergency physicians randomly assigned to two groups. The control group held a mobile phone in 'off' mode to their left ear for 15 minutes, while the intervention group held a phone in 'on' mode, exposing them to 900-1800 MHz electromagnetic waves for the same period. Total performance, total figures marked, percentile, and attention fluctuation did not differ between groups, but the intervention group missed fewer figures, made fewer incorrect marks, and showed better focus.
Wang K et al. · 2017
Researchers examined the effects of a single 30-minute exposure to 1.8 GHz radiofrequency electromagnetic radiation on recognition memory in mice, using the novel object recognition task. Exposure at an intensity above 2.2 W/kg SAR produced a significant, density-dependent increase in the recognition memory index, with no corresponding changes in spontaneous locomotor activity. The researchers also found that exposure increased dendritic-spine density and length in hippocampal and prefrontal cortical neurons, and significantly altered neuronal excitability in pyramidal neurons. The SAR used in the study was 3.3 W/kg, which the researchers noted was outside the range encountered in normal daily life.
Bodera P et al. · 2017
Researchers evaluated the effect of repeated 1800 MHz RFR exposure (5 times for 15 min) on NMDA-NR1 expression in rat brains in a persistent inflammatory state. They also measured the effect of RFR combined with tramadol to determine its potential antioxidant capacity. No differences in NMDA-NR1 expression were observed between baseline and RFR-exposed groups. NMDA-NR1 expression decreased after CFA injection combined with RFR exposure, while elevated expression was observed in healthy control rats exposed to RFR with or without tramadol. ORAC assessment revealed a robust effect of RFR, but other experiments showed equivocal effects.
Chandel S, Kaur S, Singh HP, Batish DR, Kohli RK · 2017
Researchers exposed onion roots to 2100 MHz electromagnetic field radiation for 1, 2, and 4 hours in a single day. The exposure increased levels of malondialdehyde, hydrogen peroxide, and superoxide anion, indicating oxidative stress. Antioxidant enzymes superoxide dismutase and catalase showed increased activity in response.
Mortazavi SMJ et al. · 2017
Researchers divided 50 rats into five groups and pre-exposed three groups to 915 MHz radiofrequency radiation for 4 hours daily over one week at low, medium, and high power. Twenty-four hours after the last exposure, the rats were given a 4 Gy sublethal gamma radiation dose and sacrificed after 5 hours. Pre-exposure increased glutathione levels and glutathione reductase activity in liver, with glutathione increases only in the low power group and glutathione reductase activity increases in both low and medium power groups. The elevated antioxidant levels protected liver tissue from oxidative damage induced by the gamma radiation.
Shahin S, Singh SP, Chaturvedi CM. · 2017
Researchers investigated long-term effects of 1800 MHz mobile phone radiation in stand-by, dialing, and receiving modes on female reproductive function and stress responses in mice. Exposure significantly elevated ROS, NO, lipid peroxidation, total carbonyl content, and serum corticosterone while decreasing antioxidant enzymes in the hypothalamus, ovary, and uterus. Exposed mice showed reduced developing and mature follicles and corpus lutea, along with decreased pituitary gonadotrophins, sex steroids, and expression of steroidogenic and estrogen receptor genes.
Bayat M, Hemati S, Soleimani-Estyar R, Shahin-Jafari A. · 2017
Exposed mice showed 1.5-day and 3.7-day delays in wound healing at stage two. Exposed mice also had higher yeast loads in skin lesions at days 5, 7 and 9 and were more likely to die after systemic Candida challenge, with higher kidney yeast counts.
Mortazavi SMJ et al. · 2017
Iranian researchers exposed rats to 915 MHz radiofrequency radiation (similar to microwave ovens) for 4 hours daily over one week, then tested whether this 'primed' their liver cells to better handle a subsequent dose of gamma radiation. They found that low-power RF exposure increased antioxidant enzymes like glutathione, which helped protect liver tissue from oxidative damage when the rats were later exposed to harmful gamma radiation.
Danese E et al. · 2017
Researchers exposed blood samples from 14 healthy volunteers to 900 MHz radiofrequency from a commercial mobile phone for 30 minutes. A control sample was kept away from radiofrequency sources. DNA integrity was measured by analyzing γ-H2AX foci in lymphocytes using immunofluorescence staining. No measure of γ-H2AX foci was significantly influenced by the exposure, and the odds ratio for genetic damage ranged from 0.27 to 1.00.
Park J, Kwon JH, Kim N, Song K · 2017
Researchers exposed HT22 mouse hippocampal neuronal cells and SH-SY5Y human neuroblastoma cells to 1950 MHz RF-EMF at a SAR of 6 W/kg for 2 hours per day over 3 days. They analyzed mRNA and protein expression of key genes involved in Aβ processing. In HT22 cells, mRNA levels of APP, BACE1, ADAM10 and PSEN1 decreased, while APP mRNA was unchanged in SH-SY5Y cells. Protein expression of APP and BACE1 and secreted Aβ peptide did not differ significantly between exposed and control cells.
Zhang JP et al. · 2017
Researchers exposed adolescent male mice to a 1.8 GHz radiofrequency field for 4 weeks. Depression-like behavior, spatial memory ability, and brain histology did not change obviously after exposure. Anxiety-like behavior increased, and levels of GABA and aspartic acid in the cortex and hippocampus significantly decreased.
Sırav B, Seyhan N · 2016
Turkish researchers exposed rats to cell phone radiation at 900 MHz and 1800 MHz frequencies for 20 minutes and measured how much dye leaked through the blood-brain barrier. They found that both frequencies increased brain barrier permeability in male rats, with 1800 MHz showing stronger effects, while female rats showed different response patterns.
Calvente I et al. · 2016
Calvente I et al. · 2016
Spanish researchers measured radiofrequency radiation around the homes of 123 ten-year-old boys and tested their cognitive abilities and behavior. While most measures showed no effects, boys living in areas with higher RF exposure (though still below safety guidelines) had lower verbal skills and higher rates of anxiety-related behaviors compared to those in lower exposure areas. The researchers cautioned that study limitations prevent drawing definitive conclusions.
Hardell L et al · 2016
Researchers used an exposimeter to measure radiofrequency radiation across 20 bands from 88 to 5,850 MHz at Stockholm Central Railway Station. They recorded 1,669 data points and found a median total exposure of 921 μW/m2 with mean levels varying between 2,817 and 4,891 μW/m2 per walking round. High mean measurements were observed for GSM + UMTS 900 downlink and UMTS 2100 downlink, and almost all levels exceeded the BioInitiative precautionary target of 3–6 μW/m2.
Razavinasab M, Moazzami K, Shabani M. · 2016
Researchers exposed pregnant rats to 900 MHz cell phone radiation for 6 hours daily and then tested their offspring's brain function. The exposed offspring showed reduced brain cell activity in the hippocampus (the brain's memory center) and performed worse on learning and memory tests. This suggests that cell phone exposure during pregnancy may impair brain development in offspring.
Erdem Koç G et al. · 2016
Researchers established seven groups of pregnant rats and exposed some to 900 MHz EMF for 60 minutes per day during the gestation period. After birth, male rat pups were selected and the total number of pyramidal neurons in the hippocampal region was counted using the optical fractionator technique. The total number of pyramidal cells in the EMF group was significantly lower than in the control, sham, EMF plus melatonin, and EMF plus omega-3 groups. No difference was observed between any groups in terms of rats' body or brain weights.
Erdem Koç G et al. · 2016
Pregnant rats exposed to cell phone-level radiation (900 MHz) for one hour daily produced offspring with fewer brain cells in the hippocampus, the memory center. However, melatonin and omega-3 supplements during pregnancy prevented this brain damage in the developing babies.
Erdem Koç G et al. · 2016
Turkish researchers exposed pregnant rats to cell phone radiation (900 MHz) for one hour daily throughout pregnancy, then examined brain development in their male offspring. They found that prenatal radiation exposure significantly reduced the number of pyramidal neurons in the hippocampus (a brain region critical for memory and learning). However, when pregnant rats received protective supplements like melatonin or omega-3 fatty acids alongside the radiation exposure, their offspring's brain development remained normal.
Odacı E et al. · 2016
Turkish researchers exposed pregnant rats to 900 MHz electromagnetic fields (similar to 2G cell phone radiation) for one hour daily during late pregnancy. When the offspring reached 60 days old, males showed significant reproductive damage including reduced sperm quality, increased DNA damage, and widespread cell death in the testicles.
Odacı E et al. · 2016
Researchers exposed pregnant rats to 900 MHz electromagnetic fields (similar to early cell phone frequencies) for one hour daily during late pregnancy. When the offspring reached 60 days old, males showed significantly damaged sperm quality, increased DNA damage, and widespread cell death in their reproductive organs compared to unexposed controls.
Odacı E et al. · 2016
Turkish researchers exposed pregnant rats to 900 MHz electromagnetic fields (similar to 2G cell phone frequencies) for one hour daily during late pregnancy. When the offspring reached 60 days old, males showed significantly damaged sperm quality, including reduced motility and vitality, plus increased DNA damage and cell death in their reproductive organs. This suggests prenatal EMF exposure may have lasting effects on male fertility.
Türedi S, Hancı H, Çolakoğlu S, Kaya H, Odacı E · 2016
This study examined the effects of prenatal exposure to continuous 900-MHz electromagnetic fields on ovarian development in female rat pups. Exposure during pregnancy (days 13-21) resulted in decreased numbers of primordial and tertiary follicles, increased atretic follicles and apoptosis, and histopathological changes including follicle degeneration and stromal fibrosis in the ovaries of prepubertal offspring.
