Unknown authors · 2008
Researchers investigated DNA sensitivity in peripheral blood leukocytes of radar-facility workers daily exposed to microwave radiation and unexposed controls. The study used alkaline comet assay and chromatid breakage assay to evaluate DNA damage and sensitivity. Exposed workers showed increased DNA damage by comet assay and almost three times more bleomycin-induced chromatid breaks than controls. The difference in break per cell values between smokers and non-smokers was statistically significant in the exposed group. Regression analyses revealed a significant positive correlation between the two assay results, with the best correlation between tail moment and number of chromatid breaks.
Unknown authors · 2008
The case-control study in Japan estimated specific absorption rate inside tumours using a novel approach accounting for spatial relationships. Personal interviews included 88 glioma patients, 132 meningioma patients, 102 pituitary adenoma patients, and 683 matched controls. All maximal SAR values were below 0.1 W kg−1, and adjusted odds ratios for regular mobile phone users were 1.22 for glioma and 0.70 for meningioma. When maximal SAR inside tumour tissue was accounted for, the overall odds ratio was not increased and no significant trend with SAR-derived exposure indices was found.
Unknown authors · 2008
Researchers recorded TEOAEs in 27 healthy young adults before and after 10 minutes of real or sham GSM exposure in a double-blind design. TEOAE data were analyzed both globally using broadband analysis and with wavelet transform for time-frequency fine structure. Both analyses revealed no significant effect of exposure on TEOAEs.
Unknown authors · 2008
Researchers compared mobile phone records from network operators with self-reported use for 212 cases and 296 controls across three countries over an average of two years. Mean ratios of reported to recorded use were virtually identical for cases and controls, with both groups underestimating number of calls by a factor of 0.81 and overestimating call duration by a factor of 1.4. For cases but not controls, ratios increased with increasing time before the interview, though these trends were based on few subjects with long-term data, and ratios increased by level of use. The authors concluded there was little evidence for differential recall errors overall or in recent periods, but apparent overestimation by cases in more distant time periods could cause positive bias in risk estimates.
Unknown authors · 2008
Researchers developed child head models based on magnetic resonance imaging and analyzed maximum SAR over 10 g in seven child and six adult heterogeneous head models. They also assessed SAR over 1 g in specific tissues for both child and adult head models. Simulations showed that maximum SAR over 10 g differed little between adults and children relative to variability, but maximum SAR in 1 g of peripheral brain tissue was about two times higher in child models aged 5–8 years than in adult models, with no difference for older children.
Unknown authors · 2008
The paper reviews cytogenetic biomonitoring studies of humans exposed to radiofrequency radiation. Most reviewed studies report increased frequencies of genetic damage such as chromosomal aberrations in lymphocytes or buccal cells of exposed individuals. Radiation dosimetry was lacking in all papers, and some investigations had more severe flaws.
Valbonesi P et al. · 2008
Researchers used the human trophoblast cell line HTR-8/SVneo to evaluate HSP70 and HSC70 protein and gene expression and primary DNA damage after nonthermal exposure to pulse-modulated 1817 MHz GSM-217 Hz waves for one hour at a SAR of 2 W/kg. Heat shock significantly enhanced HSP70 expression but not HSC70 expression. Exposure to high-frequency EMFs did not change HSP70 or HSC70 protein or gene expression. Hydrogen peroxide caused a significant increase in DNA strand breaks, but EMF exposure did not. Overall, no evidence was found that the exposure induced a HSP70-mediated stress response or primary DNA damage.
Tokola K, Kurttio P, Salminen T, Auvinen A. · 2008
Researchers assessed the validity of self-reported mobile phone use and developed a statistical model to account for over-reporting of exposure. They collected data from 70 volunteers using self-report interviews and network operator records. A correlation coefficient of 0.71 was found between self-reported and network operator data on average calling time. A simple linear regression model fitted the data reasonably well with an adjusted R² of 0.51.
Sadetzki S et al. · 2008
Researchers conducted a nationwide study in Israel to assess the association between cellular phone use and parotid gland tumors. For all participants, regular cellular phone use was not associated with an increased risk of parotid gland tumors. However, heavy ipsilateral use without hands-free devices showed elevated odds ratios for cumulative calls and call time.
Nieto-Hernandez R et al. · 2008
Sixty-nine participants who reported sensitivity to mobile phones took part in a double-blind, placebo-controlled provocation study. Perceived sensitivity was measured with the Sensitive Soma Assessment Scale and symptom severity was recorded. Participants were then given feedback on the overall negative findings and their individual results. Fifty-eight participants completed a 6-month follow-up and no significant differences in SSAS or symptom severity scores were found between those told they were correct or incorrect. The authors concluded that accurate feedback was insufficient to change attributions or reduce symptoms.
Lerchl A et al. · 2008
Researchers exposed adult male Djungarian hamsters to RF-EMF at 383, 900, and 1800 MHz for 60 days at 80 mW/kg. Pineal and serum melatonin levels and organ weights were not affected in any experiment. Body weight increased transiently up to 4% at 383 MHz, increased up to 6% non-transiently at 900 MHz, and was unchanged at 1800 MHz.
Lahkola A et al. · 2008
Researchers conducted an international case-control study of 1209 meningioma cases and 3299 population-based controls, identifying cases from hospitals and controls from national registers and general practitioners' lists. Detailed mobile phone use history was obtained by personal interview, assessing regular use (at least once a week for six months), duration, cumulative hours, and number of calls. Regular users showed lower meningioma risk (OR 0.76, 95% CI 0.65-0.89), with no increased risk related to years since first use, lifetime years, cumulative hours, or cumulative calls, and findings were consistent across network types, age, and sex.
Kim DW, Lee JH, Ji HC, Kim SC, Nam KC, Cha EJ. · 2008
Researchers exposed 18 self-declared EHS volunteers and 19 controls to both sham and real RF from a CDMA phone for half an hour each. They measured heart rate, respiration rate, and heart rate variability. The CDMA phone exposure produced no effects on any of these parameters in either group.
Johansson A et al. · 2008
Fifteen subjects with atopic dermatitis and 15 matched controls were exposed for 30 min to a 900 MHz GSM mobile phone-like RF field at 1 W/kg. Blood samples were taken before and after exposure to measure serum levels of substance P (SP), TNF R1, and brain derived neurotrophic factor (BDNF). At baseline, the atopic dermatitis group had significantly higher serum TNF R1 and significantly lower BDNF than controls, while SP did not differ. No effects of RF exposure were found on any of the measured substances. Symptom reports were too few to evaluate a possible correlation with exposure.
Huang TQ, Lee MS, Oh E, Zhang BT, Seo JS, Park WY. · 2008
They assessed cell proliferation, cell cycle progression, DNA damage, and gene expression. RF exposure did not significantly change cell numbers, cell cycle distribution, or DNA damage levels. Genome-wide analysis found no genes changed more than two-fold, but ten genes changed 1.3- to 1.8-fold, including down-regulation of CXCR3 and IL1R2.
Franzellitti S, Valbonesi P, Contin A, Biondi C, Fabbri E. · 2008
Researchers evaluated HSP70 gene and protein expression in human trophoblast HTR-8/SVneo cells after 4 to 24 hours of exposure to 1.8 GHz continuous-wave and GSM signals. Inducible HSP70 protein expression was not modified by any exposure condition. HSP70C transcript levels increased after 24 hours of GSM-217Hz exposure and decreased after 4 and 16 hours of GSM-Talk exposure, while HSP70A, HSP70B, and HSC70 transcripts did not change.
Falzone N et al. · 2008
Researchers exposed ejaculated, density-purified human spermatozoa to pulsed 900 MHz GSM radiation at SAR levels of 2.0 and 5.7 W/kg and compared them with controls over time. Mitochondrial membrane potential was measured by flow cytometry and showed no effect from the radiation. Sperm motility was assessed by computer-assisted sperm analysis, and all kinematic parameters were unaffected at 2.0 W/kg. At 5.7 W/kg, straight-line velocity and beat-cross frequency were significantly impaired over time (P < 0.05), with no exposure-by-time interaction. The authors state the result should not be ascribed to thermal effects due to cooling methods and temperature control.
Djeridane Y, Touitou Y, de Seze R. · 2008
Researchers exposed 20 healthy men to 900 MHz GSM radiation from a cellular phone for 2 hours per day, 5 days per week, for 4 weeks. Blood samples were taken hourly at night and every 3 hours during the day across four sessions spaced 15 days apart, using each man's pre-exposure levels as his control. All hormone levels stayed within normal ranges, and circadian patterns of prolactin, thyroid-stimulating hormone, adrenocorticotropin, and testosterone were not disrupted, while growth hormone and cortisol maximum levels decreased significantly during exposure but returned to baseline afterward.
Dasdag S, Akdag MZ, Ulukaya E, Uzunlar AK, Yegin D. · 2008
Apoptosis was assessed by immunohistochemical staining for cleaved caspase-3 in testicular tissue. The exposed group showed no statistically significant difference in apoptosis scores compared to sham and cage control groups.
Bamiou DE, Ceranic B, Cox R, Watt H, Chadwick P, Luxon LM. · 2008
The study used a double blind design with nine case subjects who reported symptoms after prolonged mobile telephone use and 21 control subjects. Each subject underwent 30 min exposures to pulsed RF, continuous RF, or no emission from a dummy phone system at 882 MHz with a maximum SAR of 1.3 W kg−1 (± 30%). Transient evoked otoacoustic emissions showed no significant changes from baseline after any exposure and no differences between cases and controls. Video-oculography detected no effect of exposure on the vestibular end organ in either group.
Unterlechner M, Sauter C, Schmid G, Zeitlhofer J · 2008
Stefanics G, Thuróczy G, Kellényi L, Hernádi I · 2008
Before and after exposure, subjects heard tone bursts while EEG was recorded and counted target tones. No significant effects were found on the amplitude or latency of N100, N200, P200, or P300 components. Early evoked gamma activity was also insensitive to the UMTS RF exposure.
Riddervold IS et al. · 2008
Forty adolescents and 40 adults were exposed to UMTS base station signals and sham conditions in a randomized, double-blinded cross-over design. Each exposure lasted 45 minutes while participants performed cognitive tasks and reported symptoms. No statistically significant differences were found between UMTS and sham conditions for the main cognitive test. An increase in headache rating was observed when combining both age groups, though this may reflect baseline differences.
Kleinlogel H et al. · 2008
Researchers tested the effects of 1950 MHz UMTS at 0.1 and 1 W/kg and pulsed 900 MHz GSM at 1 W/kg on event-related potentials and behavioral measures in 15 healthy right-handed subjects. The study used a double-blind, randomized, crossover design. Neither the UMTS- nor the GSM-EMF produced any significant changes in the measured parameters compared to sham exposure. The results do not give any evidence for a deleterious effect of the EMF on normal healthy mobile phone users.
Kleinlogel H et al. · 2008
Researchers tested 1950 MHz UMTS at SAR 0.1 and 1 W/kg and pulsed 900 MHz GSM at 1 W/kg on well-being and vigilance-controlled resting EEG in 15 healthy right-handed subjects. The study used a double-blind randomised crossover design. Neither UMTS nor GSM exposure produced significant changes in measured parameters compared to sham exposure. The results did not give evidence for a deleterious effect of the EMF on normal healthy mobile phone users.
